2019
Pocket Guide to Diagnostic Hematopathology
Hudnall S, Much M, Siddon A. Pocket Guide to Diagnostic Hematopathology. 2019 DOI: 10.1007/978-3-030-10630-0.Books
2017
Pathology of Hodgkin Lymphoma
Hudnall S. Pathology of Hodgkin Lymphoma. Molecular Pathology Library 2017, 13-34. DOI: 10.1007/978-3-319-68094-1_2.Peer-Reviewed Original ResearchReed-Sternberg cellsNodular lymphocyte predominant Hodgkin lymphomaLymphocyte predominant Hodgkin lymphomaPredominant Hodgkin lymphomaHodgkin's lymphomaClassical Reed-Sternberg cellsB cellsLP cellsMediastinal gray zone lymphomaCD4 T cellsMantle zone B cellsGray zone lymphomaReactive inflammatory infiltrateGerminal center B lymphocytesB-cell originClassical Hodgkin lymphomaB-cell immunophenotypeClonal cellsMedium-sized mononuclear cellsInflammatory infiltrateClinical featuresCastleman's diseaseHistopathologic featuresImmunophenotypic featuresReactive infiltrate
2016
Recurrent genetic defects in classical Hodgkin lymphoma cell lines
Hudnall SD, Meng H, Lozovatsky L, Li P, Strout M, Kleinstein SH. Recurrent genetic defects in classical Hodgkin lymphoma cell lines. Leukemia & Lymphoma 2016, 57: 2890-2900. PMID: 27121023, DOI: 10.1080/10428194.2016.1177179.Peer-Reviewed Original ResearchConceptsMitosis-related genesSingle nucleotide variantsCHL cell linesCell linesRecurrent genetic defectsPathogenic single nucleotide variantsHL cell linesMitotic genesChromosome duplicationClassical Hodgkin lymphoma cell linesGenomic instabilityGenetic analysisWhole-exome sequencingNucleotide variantsGenesHodgkin's lymphoma cell linesLymphoma cell linesNumber variantsKaryotypic analysisGenetic defectsWealth of informationPoor growthVariantsDuplicationLines
2014
Epstein–Barr Virus: Epidemiology and Clinical Features of Related Cancer
Hudnall S. Epstein–Barr Virus: Epidemiology and Clinical Features of Related Cancer. 2014, 25-50. DOI: 10.1007/978-1-4939-0870-7_3.Peer-Reviewed Original ResearchCell lymphomaEBV latency genesRisk of EBVEBV-positive lymphomasNK-cell lymphomasEpstein-Barr virusEndemic Burkitt lymphomaEBV gene expressionB-cell lymphomaHuman malignant tumorsImmunodeficiency-associated lymphomasApparent immunodeficiencyEBV infectionFalciparum malariaLymphoepithelial carcinomaOrgan failureClinical featuresImmunocompetent hostsLikely multifactorialSeroprevalence ratesImmunodeficient hostsMalignant tumorsSevere diseaseNasopharyngeal carcinomaBurkitt's lymphomaHuman Cancer Virology: An Historical Review
Hudnall S. Human Cancer Virology: An Historical Review. 2014, 1-6. DOI: 10.1007/978-1-4939-0870-7_1.Peer-Reviewed Original ResearchMerkel cell carcinomaCell carcinomaHepatocellular carcinomaAdult T-cell leukemia/lymphomaT-cell leukemia/lymphomaCell leukemia/lymphomaBurkitt's lymphoma tissueEpstein-Barr virusHepatitis B virusLeukemia/lymphomaHuman cancer virusesKaposi's sarcoma tissueRetrovirus HTLV-1Tumor-inducing propertiesCervical cancerHuman papillomavirusB virusHepatitis virusLymphoma tissuesHTLV-1CarcinomaSarcoma tissuesWart tissueSophisticated molecular techniquesCancer virusesEpstein–Barr Virus: Pathogenesis and Host Immune Response
Hudnall S. Epstein–Barr Virus: Pathogenesis and Host Immune Response. 2014, 7-24. DOI: 10.1007/978-1-4939-0870-7_2.Peer-Reviewed Original ResearchEpstein-Barr virusLarge double-stranded DNA genomeDouble-stranded DNA genomeInfected cellsLytic genesAnti-viral immune responsesTerminal repeat unitsCircular episomal formVirion structural componentsLinear DNA moleculesCellular S phaseLytic replicationLatent genesB cellsImmune responseRepeat unitsImmune recognitionReplication programDaughter cellsInternal repeat unitsDNA genomeGrowth signalsIcosahedral capsidTegument proteinsEBV-specific cytotoxic T cells
2012
Rare Subtypes of Extranodal T-Cell Lymphoma
Lansigan F, Hudnall S, Foss F. Rare Subtypes of Extranodal T-Cell Lymphoma. Contemporary Hematology 2012, 105-112. DOI: 10.1007/978-1-62703-170-7_7.Peer-Reviewed Original ResearchT-cell lymphomaPoor outcomePanniculitis-like T-cell lymphomaExtranodal T-cell lymphomasCytotoxic T-cell lymphomaHepatosplenic T-cell lymphomaRare T-cell lymphomaAggressive T-cell lymphomaConventional therapeutic approachesInflammatory panniculitisImmunosuppressive therapyExcellent prognosisAutoimmune disordersRare subtypeCeliac sprueTissue trophismTherapeutic approachesNew agentsLymphomaIsochromosome 7qMorphologic typesDisordersOutcomesPanniculitisPrognosisHuman herpesvirus 6 positive Reed–Sternberg cells in nodular sclerosis Hodgkin lymphoma
Siddon A, Lozovatsky L, Mohamed A, Hudnall SD. Human herpesvirus 6 positive Reed–Sternberg cells in nodular sclerosis Hodgkin lymphoma. British Journal Of Haematology 2012, 158: 635-643. PMID: 22757777, DOI: 10.1111/j.1365-2141.2012.09206.x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAgedBlotting, WesternCell Line, TumorDNA, ViralEpstein-Barr Virus InfectionsFemaleHerpesvirus 4, HumanHerpesvirus 6, HumanHodgkin DiseaseHumansImmunohistochemistryLymphoma, FollicularMaleMiddle AgedPolymerase Chain ReactionReed-Sternberg CellsRoseolovirus InfectionsSclerosisYoung AdultConceptsNodular sclerosis Hodgkin lymphomaNodular sclerosis HLHHV-6 DNAEpstein-Barr virusHHV-6Hodgkin's lymphomaReed-Sternberg cellsPolymerase chain reactionRS cellsNSHL casesEBV-negative diseaseReactive lymphoid hyperplasiaClassical Hodgkin lymphomaBi-modal age distributionHHV-6 genomeYounger patientsInfectious etiologyLymphoid hyperplasiaPCR positivityYounger ageImmunohistochemistryMost casesConflicting resultsChain reactionCD30
2011
CHAPTER 56 Human Herpesvirus Infections
Hudnall S, Stanberry L, Griffiths P. CHAPTER 56 Human Herpesvirus Infections. 2011, 355-368. DOI: 10.1016/b978-0-7020-3935-5.00056-2.Peer-Reviewed Original Research
2008
Herpesvirus prevalence and viral load in healthy blood donors by quantitative real‐time polymerase chain reaction
Hudnall SD, Chen T, Allison P, Tyring SK, Heath A. Herpesvirus prevalence and viral load in healthy blood donors by quantitative real‐time polymerase chain reaction. Transfusion 2008, 48: 1180-1187. PMID: 18422852, DOI: 10.1111/j.1537-2995.2008.01685.x.Peer-Reviewed Original ResearchConceptsEpstein-Barr virusVaricella-zoster virusHealthy adult blood donorsAdult blood donorsBlood donorsHHV-6Human herpesvirusesViral loadHHV-7Primary infectionDonor samplesMedian viral loadHHV-6 DNAHealthy blood donorsHHV-8 DNAViral DNA loadReal-time polymerase chain reactionQuantitative real-time polymerase chain reactionHerpes simplex virus 1Single-donor samplesSimplex virus 1Polymerase chain reaction assaysReal-time polymerase chain reaction assaysTransfusion recipientsActive infection
2007
Comparative flow immunophenotypic features of the inflammatory infiltrates of Hodgkin lymphoma and lymphoid hyperplasia
Hudnall SD, Betancourt E, Barnhart E, Patel J. Comparative flow immunophenotypic features of the inflammatory infiltrates of Hodgkin lymphoma and lymphoid hyperplasia. Cytometry Part B Clinical Cytometry 2007, 74B: 1-8. PMID: 18061945, DOI: 10.1002/cyto.b.20376.Peer-Reviewed Original ResearchConceptsRegulatory T cellsMixed cellularity HLReactive lymphoid hyperplasiaB cell ratioHodgkin's lymphomaReactive lymphocytic infiltrateT cellsLymphoid hyperplasiaInflammatory infiltrateB cellsCD8 ratioNKT cellsLymphocytic infiltrateHL subtypesLymph nodesImmunophenotypic featuresCell ratioMixed cellularity Hodgkin's lymphomaMalignant Reed-Sternberg cellsEBV-negative casesLymphocyte depletion subtypeRich inflammatory infiltratePercentage of CD4Fluorochrome-conjugated monoclonal antibodiesReed-Sternberg cells
2006
Chapter 57 Human Herpesvirus Infections
HUDNALL S, STANBERRY L. Chapter 57 Human Herpesvirus Infections. 2006, 590-620. DOI: 10.1016/b978-0-443-06668-9.50062-4.Peer-Reviewed Original ResearchAnatomical mapping of human herpesvirus reservoirs of infection
Chen T, Hudnall SD. Anatomical mapping of human herpesvirus reservoirs of infection. Modern Pathology 2006, 19: 726-737. PMID: 16528368, DOI: 10.1038/modpathol.3800584.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAnal CanalAutopsyCytomegalovirusDNA, ViralFemaleHerpesviridaeHerpesviridae InfectionsHerpesvirus 1, HumanHerpesvirus 2, HumanHerpesvirus 3, HumanHerpesvirus 4, HumanHerpesvirus 6, HumanHerpesvirus 7, HumanHerpesvirus 8, HumanHumansIntestinesMaleMiddle AgedNasal MucosaNervous SystemThyroid GlandConceptsHHV-6Whole blood specimensHSV-1Lymph nodesHHV-7Nasal mucosaAnatomic sitesHuman herpesvirusesHIV-AIDSActive herpesvirus infectionHSV-1 positivitySalivary glandsMajor anatomic sitesMiddle-aged malesTime of deathCardiac arrestHHV-8Adrenal glandElderly malesPrimary infectionHSV-2Urinary bladderHerpesvirus infectionAnatomical mappingBone marrow
2005
Distribution and phenotype of Epstein–Barr virus-infected cells in human pharyngeal tonsils
Hudnall SD, Ge Y, Wei L, Yang NP, Wang HQ, Chen T. Distribution and phenotype of Epstein–Barr virus-infected cells in human pharyngeal tonsils. Modern Pathology 2005, 18: 519-527. PMID: 15696119, DOI: 10.1038/modpathol.3800369.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAntigens, CDB-LymphocytesChildChild, PreschoolEpstein-Barr Virus InfectionsEpstein-Barr Virus Nuclear AntigensFemaleGene Expression Regulation, ViralHerpesvirus 4, HumanHumansImmunohistochemistryImmunophenotypingMaleMiddle AgedPalatine TonsilT-LymphocytesViral Matrix ProteinsViral ProteinsConceptsEpstein-Barr virusEBER-positive cellsT cellsHuman tonsilsNK cellsPlasma cellsEpithelial cellsB cellsBiology of EBVNK/T-cell lymphomaEpstein-Barr virus-infected cellsEBV latent protein EBNA1CD20-positive B cellsCD3-positive T cellsEarly Protein BZLF1Non-B cell typeNatural killer cellsRare T cellsT-cell lymphomaLMP1-positive cellsVirus-infected cellsMost tonsilsPlasmacytoid morphologyKiller cellsInterfollicular zones
2004
Hematologic differences in heterophile‐positive and heterophile‐negative infectious mononucleosis
Ventura KC, Hudnall SD. Hematologic differences in heterophile‐positive and heterophile‐negative infectious mononucleosis. American Journal Of Hematology 2004, 76: 315-318. PMID: 15282662, DOI: 10.1002/ajh.20119.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAgedAged, 80 and overAnimalsAntibodies, HeterophileCattleChildChild, PreschoolCross ReactionsFemaleHerpesvirus 4, HumanHumansInfectious MononucleosisLatex Fixation TestsLeukocyte CountLeukopeniaLymphocyte CountLymphocytesLymphocytosisMaleMiddle AgedRetrospective StudiesConceptsEBV-positive patientsEBV-negative patientsAbsolute lymphocyte countInfectious mononucleosisAtypical lymphocytosisLymphocyte countEpstein-Barr virus infectionEBV-negative casesEBV-negative groupTotal WBC countAgglutination test resultsAtypical lymphocytesAbsolute lymphocytosisBlood countLeukocyte countWBC countHematologic parametersVirus infectionMononucleosisHematologic differencesPatientsLymphocytosisEBVCountCauseSpecies identification of all eight human herpesviruses with a single nested PCR assay
Hudnall SD, Chen T, Tyring SK. Species identification of all eight human herpesviruses with a single nested PCR assay. Journal Of Virological Methods 2004, 116: 19-26. PMID: 14715303, DOI: 10.1016/j.jviromet.2003.10.005.Peer-Reviewed Original ResearchMeSH KeywordsCytomegalovirusDNA PrimersDNA-Directed DNA PolymeraseElectrophoretic Mobility Shift AssayHerpesviridaeHerpesvirus 1, HumanHerpesvirus 2, HumanHerpesvirus 3, HumanHerpesvirus 4, HumanHerpesvirus 6, HumanHerpesvirus 7, HumanHerpesvirus 8, HumanHeteroduplex AnalysisHumansNucleic Acid HybridizationPolymerase Chain ReactionConceptsHuman herpesvirusesPolymerase chain reactionHHV-6 subtypesClinical materialSignificant morbidityViral culturePrimary infectionLatent persistenceMultiple herpesvirusesChemiluminescent dot blot hybridizationChain reactionHeteroduplex mobilityHuman hostHerpesvirus detectionDot blot hybridizationHerpesvirusHerpesvirus DNA polymerase gene
2003
Human herpesvirus 8 seroprevalence and viral load in healthy adult blood donors
Hudnall SD, Chen T, Rady P, Tyring S, Allison P. Human herpesvirus 8 seroprevalence and viral load in healthy adult blood donors. Transfusion 2003, 43: 85-90. PMID: 12519435, DOI: 10.1046/j.1537-2995.2003.00272.x.Peer-Reviewed Original ResearchConceptsHHV-8 seroprevalenceBlood donorsDonor bloodPrimary effusion B-cell lymphomaABO blood group BHigh HHV-8 seroprevalenceHuman herpesvirus 8 seroprevalenceLatent HHV-8 antigensHealthy adult blood donorsBlood donor unitsBuffy coat DNAHHV-8 antigensHHV-8 ORF26HHV-8 viremiaSensitive indirect immunofluorescenceGeometric mean titersAdult blood donorsHHV-8 antibodiesHHV-8 DNABlood-borne virusesHuman herpesvirus 8B-cell lymphomaBlood group BDonor blood samplesHuman tumor virus
2002
Epstein-barr Virus
Yen-Moore A, Walling D, Hudnall S. Epstein-barr Virus. 2002 DOI: 10.1201/9780203910733.ch6.Peer-Reviewed Original Research
2001
Persistent Productive Epstein-Barr Virus Replication in Normal Epithelial Cells In Vivo
Walling D, Flaitz C, Nichols C, Hudnall S, Adler-Storthz K. Persistent Productive Epstein-Barr Virus Replication in Normal Epithelial Cells In Vivo. The Journal Of Infectious Diseases 2001, 184: 1499-1507. PMID: 11740724, DOI: 10.1086/323992.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusEpstein-Barr virus replicationHairy leukoplakiaEBV replicationValacyclovir treatmentVirus replicationNormal tongue tissuesPersistent EBV infectionProductive EBV replicationReverse transcriptase-polymerase chain reaction amplificationOral hairy leukoplakiaEpithelial cellsOral epithelial lesionsTongue epithelial cellsEBV infectionNormal epithelial cellsEBV DNAImmunodeficiency virusBiopsy specimensEpithelial lesionsImmunohistochemical detectionLeukoplakiaPolymerase chain reaction amplificationTongue tissueChain reaction amplificationGenetic Polymorphism (G80A) of Reduced Folate Carrier Gene in Ethnic Populations
Rady P, Szucs S, Matalon R, Grady J, Hudnall S, Kellner L, Nitowsky H. Genetic Polymorphism (G80A) of Reduced Folate Carrier Gene in Ethnic Populations. Molecular Genetics And Metabolism 2001, 73: 285-286. PMID: 11461197, DOI: 10.1006/mgme.2001.3197.Peer-Reviewed Original Research