2000
Differential Expression of the HHV-8 vGCR Cellular Homolog Gene in AIDS-Associated and Classic Kaposi's Sarcoma: Potential Role of HIV-1 Tat
Yen-Moore A, Hudnall S, Rady P, Wagner R, Moore T, Memar O, Hughes T, Tyring S. Differential Expression of the HHV-8 vGCR Cellular Homolog Gene in AIDS-Associated and Classic Kaposi's Sarcoma: Potential Role of HIV-1 Tat. Virology 2000, 267: 247-251. PMID: 10662620, DOI: 10.1006/viro.1999.0125.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeCyclin DCyclinsGene Expression Regulation, ViralGene Products, tatHerpesvirus 8, HumanHIV-1HumansLeukocytes, MononuclearOncogenesReceptors, Cell SurfaceReverse Transcriptase Polymerase Chain ReactionRNASarcoma, KaposiTat Gene Products, Human Immunodeficiency VirusTetradecanoylphorbol AcetateTumor Cells, CulturedViral ProteinsConceptsHIV-1 TatClassic Kaposi's sarcomaKaposi's sarcomaPeripheral blood mononuclear cellsAIDS-KS tissueBlood mononuclear cellsReverse transcriptase-polymerase chain reactionHuman herpesvirus 8Positive lymphoma cellsHHV-8 genesInterferon regulatory factor 1AIDS-associatedInflammatory proteinMononuclear cellsPolymerase chain reactionInterleukin-6Herpesvirus 8Regulatory factor 1SarcomaAngiogenic effectsLymphoma cellsBcl-2Factor 1Chain reactionPotential role
1998
Detection of human herpesvirus-8 DNA in Kaposi’s sarcomas from iatrogenically immunosuppressed patients
Rady P, Hodak E, Yen A, Memar O, Trattner A, Feinmesser M, David M, Hudnall S, Tyring S. Detection of human herpesvirus-8 DNA in Kaposi’s sarcomas from iatrogenically immunosuppressed patients. Journal Of The American Academy Of Dermatology 1998, 38: 429-437. PMID: 9520025, DOI: 10.1016/s0190-9622(98)70501-8.Peer-Reviewed Original ResearchConceptsKaposi's sarcomaHHV-8Polymerase chain reactionHHV-8 DNA detectionImmunosuppressed organ transplant patientsHuman herpesvirus 8 DNAOpen reading frame 26Different primary diseasesHHV-8 sequencesIatrogenic Kaposi's sarcomaOrgan transplant patientsHHV-8 DNAClassic Kaposi's sarcomaEndemic Kaposi's sarcomaFrame 26Nontransplant patientsImmunosuppressive therapyTransplant patientsAIDS-KSPrimary diseaseBiopsy specimensHigh prevalencePatientsNew herpesvirusSarcoma