Poojith Nuthalapati
Postdoctoral AssociateAbout
Research
Research at a Glance
Publications Timeline
A big-picture view of Poojith Nuthalapati's research output by year.
18Publications
36Citations
Publications
2024
Interventional Brain Medicine: Medicine's newest frontier
Nuthalapati P, Palmer C, Barbosa D, George M, Brown J. Interventional Brain Medicine: Medicine's newest frontier. 2024, 1-3. DOI: 10.61373/bm024g.0013.Peer-Reviewed Original ResearchCitationsAltmetricEx Vivo Immunization: A Strategy for Immunization Against SARS-CoV-2
Singh H, Nuthalapati P, Yendapalli P, Sahu D. Ex Vivo Immunization: A Strategy for Immunization Against SARS-CoV-2. 2024, 258-271. DOI: 10.1039/bk9781837672813-00258.Peer-Reviewed Original ResearchConceptsPeripheral blood mononuclear cellsNatural killer cellsCell-mediated immunityBlood mononuclear cellsEnhanced immune responseNaive lymphocytesDendritic cellsKiller cellsT cellsAntigen presentationB cellsMononuclear cellsImmune responseSARS-nCoV-2Human hostSignaling cascadesSARS-CoV-2Global pandemic coronavirus diseaseVirion particlesImmunityMass immunizationAdverse effectsCoronavirus 2Pandemic coronavirus diseaseNeuroinvasion by SARS-CoV-2 Influences the Prognosis of Neurological Disorders
Nuthalapati P, Ghanta M, Farran B, Chenchula S, Vedam V, Pukalendiran V, Amerneni K, Bhaskar L. Neuroinvasion by SARS-CoV-2 Influences the Prognosis of Neurological Disorders. 2024, 272-308. DOI: 10.1039/bk9781837672813-00272.Peer-Reviewed Original ResearchMultifaceted Study of a Y‑Shaped Pyrimidine Compound: Assessing Structural Properties, Docking Interactions, and Third-Order Nonlinear Optics
Potla K, Nuthalapati P, Mohan J, Osório F, Valverde C, Vankayalapati S, Adimule S, Armaković S, Armaković S, Mary Y. Multifaceted Study of a Y‑Shaped Pyrimidine Compound: Assessing Structural Properties, Docking Interactions, and Third-Order Nonlinear Optics. ACS Omega 2024, 9: 7424-7438. PMID: 38405509, PMCID: PMC10882687, DOI: 10.1021/acsomega.3c04380.Peer-Reviewed Original ResearchConceptsNonlinear optical propertiesReactivity descriptorsDocking studiesMolecular dynamicsThird-order nonlinear opticsLocal reactivity propertiesPeriodic DFT calculationsOptical propertiesNonlinear optical materialsMolecular docking studiesX-ray diffractionThird-order nonlinear susceptibilityNonlinear susceptibilityDFT calculationsFourier transform infraredNuclear magnetic resonance techniquesNoncovalent interactionsWater moleculesSpectroscopic characterizationReactivity parametersCrystal structureMD simulationsStructural characterizationOptical materialsThermal analysis
2023
Improving Seizure Frequency Documentation and Classification.
Nuthalapati P, Thomas L, Donahue M, Moura L, DeStefano S, Simpson J, Buchhalter J, Fureman B, Pellinen J. Improving Seizure Frequency Documentation and Classification. Neurology Clinical Practice 2023, 13: e200212. PMID: 37873534, PMCID: PMC10586801, DOI: 10.1212/cpj.0000000000200212.Peer-Reviewed Original ResearchCitationsAltmetricConceptsElectronic health recordsEpilepsy Learning Healthcare SystemClinic visitsLearning healthcare systemQuality of careBaseline dataQuality improvement projectBaseline data collectionEpilepsy clinicHealth recordsCase report formsDocumentation habitsImprovement projectHealthcare systemDocumentation toolsReport formsVisitsEvaluate treatment strategiesClinicData collectionSeizure documentationBaselineSeizure frequencyCritical metricsCareFeasibility and Insights from Automated Depression and Anxiety Screening for People with Epilepsy (P1-1.004)
Coelho L, Donahue M, Sevak Y, Nuthalapati P, Buchhalter J, Fureman B, Herman S, Moura L. Feasibility and Insights from Automated Depression and Anxiety Screening for People with Epilepsy (P1-1.004). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000202283.Peer-Reviewed Original ResearchCitationsAltmetricConcepts
2022
Homocysteine Levels and Clinical Outcomes in Schizophrenia—A Pilot Randomized Controlled Trial
Vedam V, Ghanta M, Kantipudi S, David D, Vijayalakshmi M, Nuthalapati P. Homocysteine Levels and Clinical Outcomes in Schizophrenia—A Pilot Randomized Controlled Trial. Journal Of Pharmacology And Pharmacotherapeutics 2022, 13: 284-292. DOI: 10.1177/0976500x221128649.Peer-Reviewed Original ResearchCitationsAltmetricConceptsBrief Psychiatric Rating ScaleBrief Psychiatric Rating Scale scoresSchizophrenia patientsAbnormal Involuntary Movement Scale scorePsychiatric Rating ScaleEfficacy of olanzapineSafety of haloperidolHomocysteine levelsOlanzapine groupHaloperidol groupSchizophrenia treatmentPeripheral bloodOlanzapineRating ScalePilot randomized controlled trialHaloperidolSchizophreniaLevels of peripheral bloodTreatment outcomesScale scoreInterventional clinical trialsBlood homocysteine levelsRandomized controlled trialsClinical outcomesRight drugAn Outbreak of Oxidative Stress in Pathogenesis of Alzheimer's Disease
Garg S, Nuthalapati P, Devi S, Sharma A, Sahu D, Gupta J. An Outbreak of Oxidative Stress in Pathogenesis of Alzheimer's Disease. 2022, 201-208. DOI: 10.1201/9781003157823-16.Peer-Reviewed Original ResearchConceptsAmyloid-bFormation of senile plaquesPathogenesis of Alzheimer's diseaseIntracellular neurofibrillary tanglesAmyloid-b peptideAlzheimer's diseaseNeurofibrillary tanglesOxidative stressSenile plaquesReactive oxygen speciesOxidative damageHallmarks of diseaseOxygen speciesNeurodegenerative ailmentsRedox-active metal ionsMetal ionsPathogenesisTanglesProteinSpeciesNanoparticles: The Promising Future of Advanced Diagnosis and Treatment of Neurological Disorders
Nuthalapati P, Asaithambi S, Kumar M, Reddy D. Nanoparticles: The Promising Future of Advanced Diagnosis and Treatment of Neurological Disorders. 2022, 221-234. DOI: 10.1201/9781003157823-18.Peer-Reviewed Original ResearchCitationsConceptsBlood-brain barrierMultiple sclerosisLimitations of current therapiesNeurological disordersParkinson's diseaseHuntington's diseaseCurrent therapiesClinical studiesTransport drugsNanoparticle strategiesIntroduction of nanotechnologyNoninvasive techniqueNanoparticle technologyDiseaseDrugDamaged nervous tissuePersistent luminescence imagingAdvanced diagnosisEtiologyGold nanoparticlesBrainDisordersNervous tissueDisease treatmentSclerosisRecent Trends in Evaluating the Mechanistic Aspects of Alzheimer's Disease and Its Diagnosis with Smart Devices
Nuthalapati P, Yendapalli P, Kumar M, Joy A, Sainatham C. Recent Trends in Evaluating the Mechanistic Aspects of Alzheimer's Disease and Its Diagnosis with Smart Devices. 2022, 25-34. DOI: 10.1201/9781003157823-3.Peer-Reviewed Original ResearchConceptsAspects of Alzheimer's diseaseHealth statusAlzheimer's diseaseLack of knowledgeLoss of cognitive abilitiesStages of Alzheimer's diseaseEarly stages of Alzheimer's diseaseAlzheimer patientsChronic neurological disorderCaregiversPatientsCognitive abilitiesMental statesDementiaDiagnosisLifestylePhysiciansHealthLow diagnostic accuracyDiseaseNeurological disordersEarly diagnosis
Academic Achievements & Community Involvement
honor Mass General Brigham PROMs Abstract Award
Other AwardMGB Office of the Chief Quality Officer’s MGB PROMs programDetails01/09/2023United Stateshonor Young Scientist Award
National AwardAndhra Pradesh Akademi of SciencesDetails03/12/2021India
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