Brainwaves
Yale School of Medicine Department of Neurology
Introducing New and Incoming Faculty
Aaron Bower, MD, will be joining the Neuro-Immunology division. Primary clinical sites will include the North Haven Interventional Immunology Center, in addition to the West Haven Veterans Affairs Hospital, where he will provide care to both general neurology and neuro-immunology patients. Outside of his clinical duties, Aaron has a passion for teaching trainees and will be pursuing a MHS in medical education over the next two years.
Xianjun Dong, PhD, is an associate professor in the Department of Neurology, with a secondary appointment in Bioinformatics and Data Science. His lab is a core component of the Adams Center for Parkinson's Disease Research. His research accomplishments are in the emerging field of noncoding RNAs and computational genomics, with a primary focus on decoding how genomic and epigenetic regulation cause neurodegenerative diseases like Parkinson's disease.
Evan Jameyfield, MD, is excited to start his career as a neuro-ophthalmologist with Yale! His clinical and research interests include the role of optical coherence tomography (OCT) in various neurological diseases and quality improvement work for patients with neuro-ophthalmologic diseases. He is also very excited for his role as a clinical educator, and he looks forward to teaching elements of the eye exam to neurology learners.
Cara Lena Crook, PhD, will be joining Yale's Clinical Neuropsychology team this fall. She is committed to patient-centered neuropsychological care across clinically and ethnoculturally diverse adult patients. Her research is focused on identifying modifiers of cognitive and functional outcomes and increasing research representation across underserved populations to advance health equity.
Anuradha Singh, MD, will be joining Yale as the clinical chief of Epilepsy and as director of the Epilepsy Center. She strongly believes that educating patients and families about their medical condition, including the limits of our understanding and capabilities, is perhaps the most important and fulfilling role a physician can play. She truly enjoys improving the patient experience and accessibility to epilepsy care for underserved populations. She likes improving workflows and operational outcomes. Her clinical interests include but are not limited to: epilepsy surgery; neuromodulation; QEEG in ICU settings; epilepsy related to stroke and brain tumors; and women with epilepsy. She likes sharing knowledge of epilepsy/EEG with trainees, EEG techs, and communities to raise awareness.
Bryan DeSouza, MD, will join the General Neurology and Headache section and will practice in Stamford and Greenwich. He graduated from Yale School of Medicine. He completed his neurology residency at Georgetown University Medical Center, and fellowship training at the NIH. Early in his career, he was an assistant professor of neurology at Allegheny University of the Health Sciences and a principal investigator in the Mayo Clinic trials, using Nerve Growth Factor for treating neuropathy. Prior to joining the department, he was in private practice and developed a career in sports neurology as the team neurologist for the Philadelphia Soul Arena Football League. He received an AAN Practice Leadership Award in sports neurology, and he is currently a member of the medical steering committee for the NFL Settlement MAF program evaluating players for neurodegenerative diseases. His clinical and research interest is in elucidating the pathophysiological mechanisms of sports-related concussions that lead to post-concussion syndromes and progress to chronic traumatic encephalopathy. He hopes that this information will inform clinical care and guide therapy.
Victor Bushlyar, MD, is an assistant professor of clinical neurology. He received his medical degree from Stony Brook University School of Medicine. He completed neurology residency at Yale New Haven Hospital and went on to complete fellowship subspecialty training in neuromuscular medicine. He provides care to patients with a broad range of neuromuscular diseases and sees patients with general neurological conditions, as well.
Stefanie Cappucci, MD, will be joining the Department of Neurology as an assistant professor in the Division of Neurocritical Care and Emergency Neurology. Originally from Watertown, Massachusetts, she completed her residency training at Beth Israel Deaconess Medical Center in Boston, and her fellowship at Yale New Haven Hospital. Her professional interests focus on the intersection of medical education and bioethics, with a particular emphasis on critical illness conversations and interdisciplinary collaboration.
Rebecca DiBiase, MD, is thrilled to join the vascular neurology faculty. She is passionate about neurologic education, as well as global neurology and stroke rehabilitation. She has worked with the new neurology residency program at the University Teaching Hospital in Zambia and is excited to maintain this relationship and to mentor trainees at Yale School of Medicine who are interested in international work. She has also learned to administer toxin injections for spasticity and looks forward to bringing her clinical skills and research in stroke recovery to the department.
NEW: 2022-2023 Annual Report
Second Annual Yale Parkinson's Disease Research and Clinical Care Symposium
In May, we hosted the Second Annual Yale Parkinson's Disease Research and Clinical Care Symposium! This all-day event featured several panel sessions aimed at promoting our clinical and research programs and efforts to expand our understanding of Parkinson's disease.
Photo Credit: Anthony DeCarlo
Navaratnam Receives the Charles W. Bohmfalk Prize for Teaching in the Basic Sciences
Professor of Neurology Dhasakumar Navaratnam, MD, PhD, (right) received the Charles W. Bohmfalk Prize for Teaching in the basic sciences from Nancy J. Brown, MD, Jean and David W. Wallace Dean of Yale School of Medicine and C.N.H. Long Professor of Internal Medicine (left), during the MD Class of 2024 Commencement. Navaratnam was one of several YSM faculty to receive a teaching award during the ceremony.
Photo Credit: Robert Lisak
Hafler Wins American Association of Immunologists Distinguished Fellow Award
David Hafler, MD (right), William S. and Lois Stiles Edgerly Professor of Neurology and Professor of Immunobiology; chair, Department of Neurology; neurologist-in-chief, Yale New Haven Hospital, receiving the American Association of Immunologists Distinguished Fellow Award from Akiko Iwasaki, PhD (left), Sterling Professor of Immunobiology and Professor of Dermatology and of Molcular, Cellular, and Developmental Biology and of Epidemiology (Microbial Diseases); investigator, Howard Hughes Medical Institute.
Featured Research Publication
News
- 6 Surprising Symptoms That Might Point to an Autoimmune DiseaseSource: SELF Magazine
- How Immunotherapy Can Treat Cancer and Other Diseases: 8 Things to KnowSource: Yale Medicine
- Epilepsy and Neurodegenerative Disorders: The Relationship Between Stroke and Seizures - WebinarSource: CURE Epilepsy (YouTube Channel)
- How to Manage Multiple Sclerosis (MS) RelapsesSource: Yale Medicine
- Being an Active Agent in your Parkinson's JourneySource: Power Over Parkinson's
- Can Exercise Help People with Parkinson’s Disease? 5 Things to KnowSource: Yale Medicine
- 11 Yale Projects Receive Awards from the Colton Center for AutoimmunitySource: Yale Ventures
- Yale’s Alzheimer’s disease research at risk of federal cutsSource: WTNH NEWS 8
- New telehealth stroke certification available to health care professionalsSource: The Associated Press
- CURRENTS: Innovation for Health Disparities Research in Hemorrhagic StrokeSource: Neurocritical Care Society Podcast
- Long COVID Brain Fog: What It Is and How to Manage ItSource: Yale Medicine
- American Stroke MonthSource: WTNH News 8
Publications
- Intravenous infusion of auto-serum-expanded autologous mesenchymal stem cells into chronic severe brain injury patientsYamaki T, Oka S, Iyama S, Sasaki M, Onodera R, Kataoka-Sasaki Y, Namioka T, Namioka A, Nakazaki M, Takemura M, Ukai R, Yokoyama T, Sasaki Y, Yamashita T, Kobayashi M, Yamaguchi M, Fukino M, Takazawa T, Hayasaka M, Owaku T, Funakura M, Onodera S, Ito Y, Kobune M, Kato J, Ishiai S, Kocsis J, Odaki M, Iwadate Y, Kobayashi S, Honmou O. Intravenous infusion of auto-serum-expanded autologous mesenchymal stem cells into chronic severe brain injury patients. Interdisciplinary Neurosurgery 2024, 36: 101927. DOI: 10.1016/j.inat.2023.101927.
- Elucidating a new path of CSF transport in the CNSBenveniste H, Thomas J. Elucidating a new path of CSF transport in the CNS. The Lancet Neurology 2024, 23: 553-554. PMID: 38760087, DOI: 10.1016/s1474-4422(24)00164-9.
- StrokeClassifier: ischemic stroke etiology classification by ensemble consensus modeling using electronic health recordsLee H, Schwamm L, Sansing L, Kamel H, de Havenon A, Turner A, Sheth K, Krishnaswamy S, Brandt C, Zhao H, Krumholz H, Sharma R. StrokeClassifier: ischemic stroke etiology classification by ensemble consensus modeling using electronic health records. Npj Digital Medicine 2024, 7: 130. PMID: 38760474, PMCID: PMC11101464, DOI: 10.1038/s41746-024-01120-w.
- SOFA score performs worse than age for predicting mortality in patients with COVID-19Sherak R, Sajjadi H, Khimani N, Tolchin B, Jubanyik K, Taylor R, Schulz W, Mortazavi B, Haimovich A. SOFA score performs worse than age for predicting mortality in patients with COVID-19. PLOS ONE 2024, 19: e0301013. PMID: 38758942, PMCID: PMC11101117, DOI: 10.1371/journal.pone.0301013.
- Impact of Poverty on Stroke Recurrence: A Population-Based Study.Becker C, Sucharew H, Robinson D, Stamm B, Royan R, Nobel L, Stanton R, Jasne A, Woo D, De Los Rios La Rosa F, Mackey J, Ferioli S, Mistry E, Demel S, Haverbusch M, Coleman E, Slavin S, Walsh K, Star M, Flaherty M, Martini S, Kissela B, Kleindorfer D. Impact of Poverty on Stroke Recurrence: A Population-Based Study. Neurology 2024, 102: e209423. PMID: 38759136, PMCID: PMC11175648, DOI: 10.1212/wnl.0000000000209423.
- Implications for driving based on the risk of seizures after ischaemic strokeMishra N. Implications for driving based on the risk of seizures after ischaemic stroke. Journal Of Neurology Neurosurgery & Psychiatry 2024, 95: 794-794. PMID: 38749673, DOI: 10.1136/jnnp-2024-333772.
- Diffusion‐Weighted Imaging Fluid‐Attenuated Inversion Recovery Mismatch on Portable, Low‐Field Magnetic Resonance Imaging Among Acute Stroke PatientsSorby‐Adams A, Guo J, de Havenon A, Payabvash S, Sze G, Pinter N, Jaikumar V, Siddiqui A, Baldassano S, Garcia‐Guarniz A, Zabinska J, Lalwani D, Peasley E, Goldstein J, Nelson O, Schaefer P, Wira C, Pitts J, Lee V, Muir K, Nimjee S, Kirsch J, Iglesias J, Rosen M, Sheth K, Kimberly W. Diffusion‐Weighted Imaging Fluid‐Attenuated Inversion Recovery Mismatch on Portable, Low‐Field Magnetic Resonance Imaging Among Acute Stroke Patients. Annals Of Neurology 2024, 96: 321-331. PMID: 38738750, PMCID: PMC11293843, DOI: 10.1002/ana.26954.
- Twenty Years of Get With The Guidelines-Stroke: Celebrating Past Successes, Lessons Learned, and Future ChallengesReeves M, Fonarow G, Smith E, Sheth K, Messe S, Schwamm L. Twenty Years of Get With The Guidelines-Stroke: Celebrating Past Successes, Lessons Learned, and Future Challenges. Stroke 2024, 55: 1689-1698. PMID: 38738376, PMCID: PMC11208062, DOI: 10.1161/strokeaha.124.046527.
- In the Eyes of the Beholder—New Mertk Knockout Mouse and Re-Evaluation of Phagocytosis versus Anti-Inflammatory Functions of MERTKGhosh S, Finnemann S, Vollrath D, Rothlin C. In the Eyes of the Beholder—New Mertk Knockout Mouse and Re-Evaluation of Phagocytosis versus Anti-Inflammatory Functions of MERTK. International Journal Of Molecular Sciences 2024, 25: 5299. PMID: 38791338, PMCID: PMC11121519, DOI: 10.3390/ijms25105299.
- Genetic mapping across autoimmune diseases reveals shared associations and mechanismsLincoln M, Connally N, Axisa P, Gasperi C, Mitrovic M, van Heel D, Wijmenga C, Withoff S, Jonkers I, Padyukov L, Rich S, Graham R, Gaffney P, Langefeld C, Vyse T, Hafler D, Chun S, Sunyaev S, Cotsapas C. Genetic mapping across autoimmune diseases reveals shared associations and mechanisms. Nature Genetics 2024, 56: 838-845. PMID: 38741015, DOI: 10.1038/s41588-024-01732-8.
- Updated safety results from phase 3 lecanemab study in early Alzheimer’s diseaseHonig L, Sabbagh M, van Dyck C, Sperling R, Hersch S, Matta A, Giorgi L, Gee M, Kanekiyo M, Li D, Purcell D, Dhadda S, Irizarry M, Kramer L. Updated safety results from phase 3 lecanemab study in early Alzheimer’s disease. Alzheimer's Research & Therapy 2024, 16: 105. PMID: 38730496, PMCID: PMC11084061, DOI: 10.1186/s13195-024-01441-8.
- A review of the kappa opioid receptor system in opioid useCayir S, Zhornitsky S, Barzegary A, Sotomayor-Carreño E, Sarfo-Ansah W, Funaro M, Matuskey D, Angarita G. A review of the kappa opioid receptor system in opioid use. Neuroscience & Biobehavioral Reviews 2024, 162: 105713. PMID: 38733895, DOI: 10.1016/j.neubiorev.2024.105713.
- Author Correction: A multi-ancestry genetic study of pain intensity in 598,339 veteransToikumo S, Vickers-Smith R, Jinwala Z, Xu H, Saini D, Hartwell E, Pavicic M, Sullivan K, Xu K, Jacobson D, Gelernter J, Rentsch C, Stahl E, Cheatle M, Zhou H, Waxman S, Justice A, Kember R, Kranzler H. Author Correction: A multi-ancestry genetic study of pain intensity in 598,339 veterans. Nature Medicine 2024, 30: 2088-2088. PMID: 38714900, DOI: 10.1038/s41591-024-03024-4.
- Use of a dedicated open transcarotid access system for neurovascular diseaseSujijantarat N, Renedo D, Antonios J, Koo A, Amllay A, Nowicki K, Cord B, Hebert R, de Havenon A, Sheth K, Petersen N, Matouk C. Use of a dedicated open transcarotid access system for neurovascular disease. Journal Of NeuroInterventional Surgery 2024, jnis-2024-021599. PMID: 38719442, DOI: 10.1136/jnis-2024-021599.
- Racial Disparities in Blood Pressure at Time of Acute Ischemic Stroke Presentation: A Population StudyAziz Y, Sucharew H, Stanton R, Alwell K, Ferioli S, Khatri P, Adeoye O, Flaherty M, Mackey J, La Rosa F, Martini S, Mistry E, Coleman E, Jasne A, Slavin S, Walsh K, Star M, Ridha M, Ades L, Haverbusch M, Demel S, Woo D, Kissela B, Kleindorfer D. Racial Disparities in Blood Pressure at Time of Acute Ischemic Stroke Presentation: A Population Study. Journal Of The American Heart Association 2024, 13: e032645. PMID: 38700029, PMCID: PMC11179936, DOI: 10.1161/jaha.123.032645.
- 2024 AHA/ASA Performance and Quality Measures for Spontaneous Intracerebral Hemorrhage: A Report From the American Heart Association/American Stroke AssociationRuff I, de Havenon A, Bergman D, Dugue R, Frontera J, Goldstein J, Hemphill J, Marulanda-Londono E, Prabhakaran S, Richards C, Sunmonu N, Vilar P, Wolfe S. 2024 AHA/ASA Performance and Quality Measures for Spontaneous Intracerebral Hemorrhage: A Report From the American Heart Association/American Stroke Association. Stroke 2024, 55: e199-e230. PMID: 38695183, DOI: 10.1161/str.0000000000000464.
- Treatment of Refractory Status Epilepticus With Continuous Intravenous Anesthetic DrugsAu Y, Kananeh M, Rahangdale R, Moore T, Panza G, Gaspard N, Hirsch L, Fernandez A, Shah S. Treatment of Refractory Status Epilepticus With Continuous Intravenous Anesthetic Drugs. JAMA Neurology 2024, 81: 534-548. PMID: 38466294, DOI: 10.1001/jamaneurol.2024.0108.
- Blood Pressure and Cognitive Function in Older AdultsLittig L, Sheth K, Brickman A, Mistry E, de Havenon A. Blood Pressure and Cognitive Function in Older Adults. Clinics In Geriatric Medicine 2024, 40: 597-613. PMID: 39349034, PMCID: PMC11443062, DOI: 10.1016/j.cger.2024.04.003.
- 434. Improving Image Accuracy in Low-Field Magnetic Resonance Imaging to Make Accessible Biomarkers for Psychiatric DisordersCooper R, Hayes R, Corcoran M, Sheth K, Arnold T, Stein J, Glahn D, Jalbrzikowski M. 434. Improving Image Accuracy in Low-Field Magnetic Resonance Imaging to Make Accessible Biomarkers for Psychiatric Disorders. Biological Psychiatry 2024, 95: s277-s278. DOI: 10.1016/j.biopsych.2024.02.933.
- 37. The Structural Connectome Constrains in Vivo Synaptic Density Loss in SchizophreniaChopra S, Worhunsky P, Naganawa M, Angarita G, Cosgrove K, D'Souza D, Matuskey D, Nabulsi N, Huang Y, Carson R, Esterlis I, Skosnik P, Holmes A, Radhakrishnan R. 37. The Structural Connectome Constrains in Vivo Synaptic Density Loss in Schizophrenia. Biological Psychiatry 2024, 95: s90. DOI: 10.1016/j.biopsych.2024.02.215.
- Translational PET Imaging of HDAC6 Using 18F-Bavarostat in PTSDBonomi R, Girgenti M, Naganawa M, Matuskey D, Cosgrove K. Translational PET Imaging of HDAC6 Using 18F-Bavarostat in PTSD. Biological Psychiatry 2024, 95: s40-s41. DOI: 10.1016/j.biopsych.2024.02.102.
- Radiomic Features of Acute Cerebral Hemorrhage on Non-Contrast CT Associated with Patient SurvivalZaman S, Dierksen F, Knapp A, Haider S, Karam G, Qureshi A, Falcone G, Sheth K, Payabvash S. Radiomic Features of Acute Cerebral Hemorrhage on Non-Contrast CT Associated with Patient Survival. Diagnostics 2024, 14: 944. PMID: 38732358, PMCID: PMC11083693, DOI: 10.3390/diagnostics14090944.
- Design and implementation of community consultation for research conducted under exception from informed consent regulations for the PreVent and the PreVent 2 trials: Changes over time and during the COVID-19 pandemicGugel T, Adams K, Baranoski M, Yanez N, Kampp M, Johnson T, Aydin A, Fajardo E, Sharp E, Potnis A, Johnson C, Treggiari M. Design and implementation of community consultation for research conducted under exception from informed consent regulations for the PreVent and the PreVent 2 trials: Changes over time and during the COVID-19 pandemic. Clinical Trials 2024, 21: 671-680. PMID: 38676438, PMCID: PMC11512686, DOI: 10.1177/17407745241243045.
- Relationship between neuroimaging and cognition in frontotemporal dementia: An FDG‐PET and structural MRI studyCayir S, Volpi T, Toyonaga T, Gallezot J, Yang Y, Sadabad F, Mulnix T, Mecca A, Fesharaki‐Zadeh A, Matuskey D. Relationship between neuroimaging and cognition in frontotemporal dementia: An FDG‐PET and structural MRI study. Journal Of Neuroimaging 2024, 34: 627-634. PMID: 38676301, PMCID: PMC11511789, DOI: 10.1111/jon.13206.
- Trends in the Use of Medications for Secondary Ischemic Stroke Prevention in Denmark, 2005-2021.Skajaa N, Laugesen K, Lauffenburger J, Schwamm L, Sørensen H, Patorno E. Trends in the Use of Medications for Secondary Ischemic Stroke Prevention in Denmark, 2005-2021. Neurology 2024, 102: e209309. PMID: 38648572, PMCID: PMC11226314, DOI: 10.1212/wnl.0000000000209309.
- Secondary Prevention in Patients With Stroke Versus Myocardial Infarction: Analysis of 2 National CohortsRivier C, Acosta J, Leasure A, Forman R, Sharma R, de Havenon A, Spatz E, Inzucchi S, Kernan W, Falcone G, Sheth K. Secondary Prevention in Patients With Stroke Versus Myocardial Infarction: Analysis of 2 National Cohorts. Journal Of The American Heart Association 2024, 13: e033322. PMID: 38639369, PMCID: PMC11179946, DOI: 10.1161/jaha.123.033322.
- Case-Control Study of Individuals With Small Fiber Neuropathy After COVID-19McAlpine L, Zubair A, Joseph P, Spudich S. Case-Control Study of Individuals With Small Fiber Neuropathy After COVID-19. Neurology Neuroimmunology & Neuroinflammation 2024, 11: e200244. PMID: 38630952, PMCID: PMC11087026, DOI: 10.1212/nxi.0000000000200244.
- Impact of sleep quality and physical activity on blood pressure variabilityde Havenon A, Falcone G, Rivier C, Littig L, Petersen N, de Villele P, Prabhakaran S, Kimberly W, Mistry E, Sheth K. Impact of sleep quality and physical activity on blood pressure variability. PLOS ONE 2024, 19: e0301631. PMID: 38625967, PMCID: PMC11020843, DOI: 10.1371/journal.pone.0301631.
- Cerebral edema following cardiac arrest: Are all shades of gray equal?Beekman R, Gilmore E. Cerebral edema following cardiac arrest: Are all shades of gray equal? Resuscitation 2024, 198: 110213. PMID: 38636600, DOI: 10.1016/j.resuscitation.2024.110213.
- Comparative analysis of patients with new onset refractory status epilepticus preceded by fever (febrile infection‐related epilepsy syndrome) versus without prior fever: An interim analysisJimenez A, Gopaul M, Asbell H, Aydemir S, Basha M, Batra A, Damien C, Day G, Eka O, Eschbach K, Fatima S, Fields M, Foreman B, Gerard E, Gofton T, Haider H, Hantus S, Hocker S, Jongeling A, Aparicio M, Kandula P, Kang P, Kazazian K, Kellogg M, Kim M, Lee J, Marcuse L, McGraw C, Mohamed W, Orozco J, Pimentel C, Punia V, Ramirez A, Steriade C, Struck A, Taraschenko O, Treister A, Yoo J, Zafar S, Zhou D, Zutshi D, Gaspard N, Hirsch L, Hanin A. Comparative analysis of patients with new onset refractory status epilepticus preceded by fever (febrile infection‐related epilepsy syndrome) versus without prior fever: An interim analysis. Epilepsia 2024, 65: e87-e96. PMID: 38625055, DOI: 10.1111/epi.17988.
- Prognostic Implications of Early Prediction in Posttraumatic EpilepsyChen Y, Cappucci S, Kim J. Prognostic Implications of Early Prediction in Posttraumatic Epilepsy. Seminars In Neurology 2024, 44: 333-341. PMID: 38621706, DOI: 10.1055/s-0044-1785502.
- Comparative analysis of energy expenditure and costs in neuroimagingSignorile W, Mahajan A, Fulbright R, Zubair A. Comparative analysis of energy expenditure and costs in neuroimaging. Journal Of The Neurological Sciences 2024, 460: 123001. PMID: 38616465, DOI: 10.1016/j.jns.2024.123001.
- External validation of the SI2NCAL2C score for outcomes following cerebral venous thrombosisKlein P, Shu L, Lindgren E, de Winter M, Siegler J, Simpkins A, Omran S, Heldner M, de Havenon A, Abdalkader M, Al Kasab S, Stretz C, Wu T, Wilson D, Asad S, Almallouhi E, Frontera J, Kuohn L, Rothstein A, Bakradze E, Henninger N, Zubair A, Sharma R, Kerrigan D, Aziz Y, Mistry E, van Kammen M, Tatlisumak T, Krzywicka K, Aguiar de Sousa D, Jood K, Field T, Yaghi S, Coutinho J, Nguyen T. External validation of the SI2NCAL2C score for outcomes following cerebral venous thrombosis. Journal Of Stroke And Cerebrovascular Diseases 2024, 33: 107720. PMID: 38614162, DOI: 10.1016/j.jstrokecerebrovasdis.2024.107720.
- An overview of preclinical models of traumatic brain injury (TBI): relevance to pathophysiological mechanismsFesharaki-Zadeh A, Datta D. An overview of preclinical models of traumatic brain injury (TBI): relevance to pathophysiological mechanisms. Frontiers In Cellular Neuroscience 2024, 18: 1371213. PMID: 38682091, PMCID: PMC11045909, DOI: 10.3389/fncel.2024.1371213.
- Contemporary management of aneurysmal subarachnoid haemorrhage. An update for the intensivistRobba C, Busl K, Claassen J, Diringer M, Helbok R, Park S, Rabinstein A, Treggiari M, Vergouwen M, Citerio G. Contemporary management of aneurysmal subarachnoid haemorrhage. An update for the intensivist. Intensive Care Medicine 2024, 50: 646-664. PMID: 38598130, PMCID: PMC11078858, DOI: 10.1007/s00134-024-07387-7.
- Chronic Kidney Disease and Risk of Intracerebral Hemorrhage: The Role of Hypertension as a Mediator (S34.004)Vanent K, Rivier C, Matouk C, Levitt M, Leslie-Mazwi T, Gill T, Sheth K, Falcone G. Chronic Kidney Disease and Risk of Intracerebral Hemorrhage: The Role of Hypertension as a Mediator (S34.004). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000205783.
- Brain Health Outcomes in Sexual and Gender Minority Groups (S14.002)Huo S, Rivier C, Clocchiatti-Tuozzo S, Renedo D, Sunmonu N, De Havenon A, Sheth K, Falcone G. Brain Health Outcomes in Sexual and Gender Minority Groups (S14.002). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000205825.
- Polygenic Resistance to Blood Pressure Treatment and Stroke Risk (S6.001)Huo S, Rivier C, Clocchiatti-Tuozzo S, Renedo D, Zhao H, De Havenon A, Sheth K, Falcone G. Polygenic Resistance to Blood Pressure Treatment and Stroke Risk (S6.001). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000206202.
- Enhanced Benefits of the Life’s Essential 8 in APOE Epsilon 4 Carriers (P3-5.014)Clocchiatti-Tuozzo S, Rivier C, Renedo D, Huo S, Torres-Lopez V, De Havenon A, Sheth K, Gill T, Falcone G. Enhanced Benefits of the Life’s Essential 8 in APOE Epsilon 4 Carriers (P3-5.014). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000206215.
- Oral Health as a Risk Factor for Spontaneous Intracerebral Hemorrhage: A Mendelian Randomization Analysis (S34.001)Rivier C, Clocchiatti-Tuozzo S, Huo S, Renedo D, Hawkes M, Sunmonu N, Sheth K, Falcone G. Oral Health as a Risk Factor for Spontaneous Intracerebral Hemorrhage: A Mendelian Randomization Analysis (S34.001). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000204999.
- Life’s Essential 8 and Brain Health Clinical Outcomes in Middle-aged Adults (P2-15.003)Clocchiatti-Tuozzo S, Rivier C, Renedo D, Huo S, Torres-Lopez V, De Havenon A, Sheth K, Gill T, Falcone G. Life’s Essential 8 and Brain Health Clinical Outcomes in Middle-aged Adults (P2-15.003). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000206195.
- Epigenetic Age and Brain Health Events: Findings from the Health and Retirement Study (P2-9.004)Rivier C, Szejko N, Renedo D, De Havenon A, Sheth K, Gill T, Falcone G. Epigenetic Age and Brain Health Events: Findings from the Health and Retirement Study (P2-9.004). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000204975.
- Factors Associated with Delayed Clinical Evaluation for Patients with Intracerebral Hemorrhage in the ERICH Study (S41.010)Lalwani D, Zabinska J, Peasley E, De Havenon A, Falcone G, Goldstein J, Woo D, Sheth K. Factors Associated with Delayed Clinical Evaluation for Patients with Intracerebral Hemorrhage in the ERICH Study (S41.010). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000204689.
- Quantitative Assessment of Reperfusion Impact on Cerebral Edema and Functional Outcomes in Large-vessel Occlusion Stroke Patients (S23.003)Olexa M, Begunova Y, Dhar R, Matouk C, Sheth K, Gutierrez S, De Havenon A, Petersen N. Quantitative Assessment of Reperfusion Impact on Cerebral Edema and Functional Outcomes in Large-vessel Occlusion Stroke Patients (S23.003). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000205719.
- The Effectiveness of Neurologic Telehealth Outpatient Care During the COVID-19 Pandemic (P1-10.001)Hill C, Lin C, Anderson-Benge E, Esper C, Nair K, De Havenon A, Busis N, Esper G, Callaghan B. The Effectiveness of Neurologic Telehealth Outpatient Care During the COVID-19 Pandemic (P1-10.001). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000206056.
- Disparities in Healthcare Interactions After Intracerebral Hemorrhage: Evidence from the REDUCE Trial (P3-5.020)Zabinska J, Taylor C, Peasley E, Lalwani D, Schwartz A, Falcone G, Sansing L, Arora R, Mena-Hurtado C, De Havenon A, Okpala M, Bushnell C, Mullen M, Cohen J, Cohen D, Messe S, Forman R, Sheth K. Disparities in Healthcare Interactions After Intracerebral Hemorrhage: Evidence from the REDUCE Trial (P3-5.020). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000206241.
- Exploring the Relationship Between Cerebrospinal Fluid Interleukin-6 and Cerebral Autoregulation After Subarachnoid Hemorrhage (S23.004)Olexa M, Begunova Y, Gilmore E, Kim J, Herman A, Beekman R, Magid-Bernstein J, Matouk C, Sheth K, Miller E, Gutierrez S, De Havenon A, Sansing L, Petersen N. Exploring the Relationship Between Cerebrospinal Fluid Interleukin-6 and Cerebral Autoregulation After Subarachnoid Hemorrhage (S23.004). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000205692.
- Different Response to Blood Pressure Reduction in Lobar and Deep Intracerebral Hemorrhage (P10-2.004)Hawkes M, Clocchiatti-Tuozzo S, Rivier C, Qureshi A, Matouk C, Petersen N, De Havenon A, Sheth K, Falcone G. Different Response to Blood Pressure Reduction in Lobar and Deep Intracerebral Hemorrhage (P10-2.004). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000206366.
- Evaluating Sleep Apnea Risk in Survivors of Intracerebral Hemorrhage in the REDUCE Cohort (P9-9.002)Peasley E, Geer J, Zabinska J, Forman R, Lalwani D, Schwartz A, Falcone G, Sansing L, Arora R, Mena-Hurtado C, De Havenon A, Okpala M, Bushnell C, Mullen M, Cohen J, Cohen D, Messe S, Sheth K. Evaluating Sleep Apnea Risk in Survivors of Intracerebral Hemorrhage in the REDUCE Cohort (P9-9.002). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000205685.
- Prognostication of Outcomes in Stroke Patients Using Inflammatory Biomarkers: Findings from the Yale Post-stroke Epilepsy Research Group (P3-5.010)Wang E, Misra S, Yan J, Chook P, Kawamura Y, Kitagawa R, Kim J, Gilmore E, De Havenon A, Sivaraju A, Hirsch L, Falcone G, Sansing L, Magid-Bernstein J, Mishra N. Prognostication of Outcomes in Stroke Patients Using Inflammatory Biomarkers: Findings from the Yale Post-stroke Epilepsy Research Group (P3-5.010). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000204783.
- Neighborhood Deprivation and Functional Outcomes Following Ischemic Stroke (P2-4.007)Kleinberg L, Clocchiatti-Tuozzo S, Rivier C, Torres-Lopez V, Kim J, Kitlen E, Kampp M, Jasak S, Schindler J, Sansing L, Sheth K, Falcone G. Neighborhood Deprivation and Functional Outcomes Following Ischemic Stroke (P2-4.007). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000205095.
- Association of CT-based Lobar Contusion Volumes and Locations with Post-traumatic Epilepsy (P5-1.003)Shrishail N, Wheelock J, Sanders W, Doherty D, Kim J, Schlecter M, Sivaraju A, Hirsch L, Omay S, Sheth K, Gilmore E, Edlow B, Kim J. Association of CT-based Lobar Contusion Volumes and Locations with Post-traumatic Epilepsy (P5-1.003). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000206260.
- Assessing Effects of Intrathecal Nicardipine on Cerebral Autoregulation and Cortical Activity in Aneurysmal Subarachnoid Hemorrhage (P10-5.019)Jayasundara S, Kim J, Choi R, Rapuano A, Barnes E, Parasram M, Moura M, Uppal P, Chen Y, Top I, Olexa M, Maarek R, Yan J, Beekman R, Magid-Bernstein J, Hebert R, Bahrassa F, Matouk C, Sheth K, Gilmore E, Petersen N. Assessing Effects of Intrathecal Nicardipine on Cerebral Autoregulation and Cortical Activity in Aneurysmal Subarachnoid Hemorrhage (P10-5.019). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000206285.
- Low-field, Portable Magnetic Resonance Imaging to Assess Hematoma Volume in Traumatic Brain Injury Patients (P10-5.008)Zabinska J, Yadlapalli V, Mazurek M, Parasuram N, Lalwani D, Peasley E, Gilmore E, Kim J, Omay S, Sze G, Payabvash S, Sorby-Adams A, Iglesias J, Rosen M, Kimberly W, Sheth K. Low-field, Portable Magnetic Resonance Imaging to Assess Hematoma Volume in Traumatic Brain Injury Patients (P10-5.008). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000208210.
- Phenotypes of B Cells Producing Autoantibodies in MOGAD Patients (N1.002)Filipek B, Yandamuri S, Obaid A, Thurman J, Makhani N, Nowak R, Guo Y, Lucchinetti C, Flanagan E, Longbrake E, O’Connor K. Phenotypes of B Cells Producing Autoantibodies in MOGAD Patients (N1.002). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000208259.
- Focal White Matter Damage in Individuals with Cognitive Impairment After COVID-19 (P11-13.004)McAlpine L, Nelson A, Chiarella J, Lacadie C, Farhadian S, Constable T, Spudich S. Focal White Matter Damage in Individuals with Cognitive Impairment After COVID-19 (P11-13.004). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000204666.
- Proteomic Analysis Reveals a Distinct Immunological Signature for Late-onset Myasthenia Gravis (S15.003)Roy B, Habiabadi F, O’Connor K, Nowak R, Kaminski H. Proteomic Analysis Reveals a Distinct Immunological Signature for Late-onset Myasthenia Gravis (S15.003). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000205944.
- Investigating Metabotropic Glutamate Receptor 5 (mGluR5) in Autism Spectrum Disorder with [18F]FPEB PET Imaging (S8.007)Sadabad F, Yang Y, Gravel P, Naples A, Torres K, Nabulsi N, Ropchan J, Huang Y, Hillmer A, Esterlis I, Carson R, Mcpartland J, Matuskey D. Investigating Metabotropic Glutamate Receptor 5 (mGluR5) in Autism Spectrum Disorder with [18F]FPEB PET Imaging (S8.007). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000206171.
- Measuring Synaptic Density and Dopamine Transporter Availability in Parkinson's Disease: A PET Imaging Study with 11C-UCB-J and 18F-FE-PE2I (P7-3.007)Saadabad F, Volpi T, Honhar P, Naganawa M, Cayir S, Tinaz S, Gallezot J, angarita G, Holmes S, Carson R, Finnema S, Matuskey D. Measuring Synaptic Density and Dopamine Transporter Availability in Parkinson's Disease: A PET Imaging Study with 11C-UCB-J and 18F-FE-PE2I (P7-3.007). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000205367.
- Can Clinical Scores Predict the Presence of Hypoxic Ischemic Brain Injury on Early Head Computed Tomography After Cardiac Arrest? (P6-2.001)Nguyen C, Molligoda B, Kim N, Kitlen E, Wira C, Perman S, Khosla A, Miller P, Greer D, Gilmore E, Beekman R. Can Clinical Scores Predict the Presence of Hypoxic Ischemic Brain Injury on Early Head Computed Tomography After Cardiac Arrest? (P6-2.001). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000206255.
- Antiseizure Medications in Post-stroke Seizures: A Systematic Review and Network Meta-analysis (P8-1.012)Misra S, Dawson J, Kwan P, Kasner S, Grotta J, Larsson D, Tanaka T, Zaveri H, Wang S, Khan E, Funaro M, Perla S, Dev P, Hussain T, Liebeskind D, Yasuda C, Elshahat A, Hitawala G, Wang E, Kitagawa R, Pathak A, Zhao Y, Scalzo F, Ihara M, Zelano J, Sunnerhagen K, Walters M, Jette N, Quinn T, Mishra N. Antiseizure Medications in Post-stroke Seizures: A Systematic Review and Network Meta-analysis (P8-1.012). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000205632.
- The Impact of Socioeconomic Status on Risk for Brain Death Following Out-of-Hospital Cardiac Arrest (P1-4.014)Fung C, Kitlen E, Nguyen C, Kim N, Wira C, Perman S, Khosla A, Miller P, Greer D, Gilmore E, Beekman R. The Impact of Socioeconomic Status on Risk for Brain Death Following Out-of-Hospital Cardiac Arrest (P1-4.014). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000206574.
- A Brain Care Score to Mitigate the Genetic Risk of Adverse Brain Health Outcomes (S16.010)Kimball T, Mayerhofer E, Senff J, Marini S, Rivier C, Kourkoulis C, Oreskovic T, Carr S, Falcone G, Yechoor N, Rosand J, Singh S, Parodi L, Anderson C. A Brain Care Score to Mitigate the Genetic Risk of Adverse Brain Health Outcomes (S16.010). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000206517.
- Characterizing the Effects of Progranulin Reduction on Tau Pathology and Phenotypes in a Mouse Model of Tauopathy (P4-9.016)Bhagwagar S, Takahashi H, Strittmatter S. Characterizing the Effects of Progranulin Reduction on Tau Pathology and Phenotypes in a Mouse Model of Tauopathy (P4-9.016). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000205227.
- First Reported Case of Tenecteplase for Pediatric Acute Ischemic Stroke (P7-5.021)Elmashad A, Fung C, Chakravartty A, Mehta A, Hebert R, Beekman R, Sunmonu N. First Reported Case of Tenecteplase for Pediatric Acute Ischemic Stroke (P7-5.021). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000205076.
- Variability in Brain Death Education Across US Neurology Residency Programs (P6-7.008)Doobay G, Barnes E, Moeller J, Gilmore E, Beekman R. Variability in Brain Death Education Across US Neurology Residency Programs (P6-7.008). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000206169.
- Association of Acute Carotid Stenting with Functional Outcome Mediated by Successful Reperfusion in Tandem Lesions: Mediation Analysis of a Multicenter Registry (P2-5.006)Rodriguez-Calienes A, Galecio-Castillo M, Hassan A, Jumaa M, Divani A, Ribo M, Abraham M, Petersen N, Fifi J, Guerrero W, Malik A, Siegler J, Nguyen T, Sheth S, Yoo A, Linares G, Janjua N, Quispe-Orozco D, Lu Y, Vivanco-Suarez J, Dibas M, Mokin M, Yavagal D, Ortega-Gutierrez S. Association of Acute Carotid Stenting with Functional Outcome Mediated by Successful Reperfusion in Tandem Lesions: Mediation Analysis of a Multicenter Registry (P2-5.006). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000206545.
- Mechanical Thrombectomy in Tandem Lesion: Effects of Extracranial Carotid Dissection Versus Atherosclerosis (S6.006)Quispe-Orozco D, Galecio-Castillo M, Jumaa M, Divani A, Ribo M, Abraham M, Petersen N, Fifi J, Guerrero W, Malik A, Siegler J, Nguyen T, Sheth S, Yoo A, Linares G, Janjua N, Tekle W, Abdalkader M, Soomro J, Vivanco-Suarez J, Rodriguez-Calienes A, Mokin M, Yavagal D, Hassan A, Gutierrez S. Mechanical Thrombectomy in Tandem Lesion: Effects of Extracranial Carotid Dissection Versus Atherosclerosis (S6.006). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000206570.
- Association Between Intraprocedural Drops in Blood Pressure and Infarct Growth Rate Patterns After Acute Large-vessel Occlusions (S34.003)Galecio-Castillo M, Orozco D, Dajles A, Begunova Y, Rodriguez-Calienes A, Vivanco-Suarez J, Dibas M, Petersen N, Gutierrez S. Association Between Intraprocedural Drops in Blood Pressure and Infarct Growth Rate Patterns After Acute Large-vessel Occlusions (S34.003). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000208243.
- Preliminary Characterization of Language Network Connectivity in a Logopenic Alzheimer’s Population Using Task-based fMRI (S1.006)Oland L, Trainer A, Ficek-Tani B, Li J, Tun S, Ju S, Lacadie C, Constable T, Martin N, Fredericks C. Preliminary Characterization of Language Network Connectivity in a Logopenic Alzheimer’s Population Using Task-based fMRI (S1.006). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000204401.
- Investigating the Relationships of Atrophy and Hypometabolism on Cognitive Decline in Frontotemporal Dementia (P1-9.018)Cayir S, Yang Y, Volpi T, Sadabad F, Toyonaga T, Gallezot J, Mecca A, Fesharaki-Zadeh A, Matuskey D. Investigating the Relationships of Atrophy and Hypometabolism on Cognitive Decline in Frontotemporal Dementia (P1-9.018). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000204352.
- Machine Learning-informed Subtyping of Generalized Periodic Discharges in Cardiac Arrest (S23.006)Karukonda V, Aghaeeaval M, Kandhare P, Zheng W, Jing J, Ghassemi M, Lee J, Herman S, Sivaraju A, Gaspard N, Hofmeijer J, van Putten M, Westover M, Amorim E. Machine Learning-informed Subtyping of Generalized Periodic Discharges in Cardiac Arrest (S23.006). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000204918.
- Post-COVID Conditions in People with Multiple Sclerosis: A Cross-sectional Multicenter Study (P1-6.002)Son J, Hu C, McAlpine L, Bar-Or A, Dahl M, Brito S, Kavak K, Onomichi K, Perrone C, Riley C, Song E, Walker E, Weinstock-Guttman B, De Jager P, Longbrake E, Xia Z. Post-COVID Conditions in People with Multiple Sclerosis: A Cross-sectional Multicenter Study (P1-6.002). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000205595.
- Non-dominant, Lesional Mesial Temporal Lobe EpilepsyMahmoud N, Herlopian A, Mattson R. Non-dominant, Lesional Mesial Temporal Lobe Epilepsy. 2024, 47-61. DOI: 10.1007/978-3-031-23828-4_3.
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- Dominant, Lesional Temporal Pole EpilepsyHerlopian A. Dominant, Lesional Temporal Pole Epilepsy. 2024, 87-103. DOI: 10.1007/978-3-031-23828-4_5.
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- Temperature Control Parameters Are Important: Earlier Preinduction Is Associated With Improved Outcomes Following Out-of-Hospital Cardiac ArrestBeekman R, Kim N, Nguyen C, McGinniss G, Deng Y, Kitlen E, Garcia G, Wira C, Khosla A, Johnson J, Miller P, Perman S, Sheth K, Greer D, Gilmore E. Temperature Control Parameters Are Important: Earlier Preinduction Is Associated With Improved Outcomes Following Out-of-Hospital Cardiac Arrest. Annals Of Emergency Medicine 2024, 84: 549-559. PMID: 39033449, DOI: 10.1016/j.annemergmed.2024.06.007.
- Association of Early Dexmedetomidine Utilization With Clinical Outcomes After Moderate-Severe Traumatic Brain Injury: A Retrospective Cohort StudyLiu S, Kelly-Hedrick M, Komisarow J, Hatfield J, Ohnuma T, Treggiari M, Colton K, Arulraja E, Vavilala M, Laskowitz D, Mathew J, Hernandez A, James M, Raghunathan K, Krishnamoorthy V. Association of Early Dexmedetomidine Utilization With Clinical Outcomes After Moderate-Severe Traumatic Brain Injury: A Retrospective Cohort Study. Anesthesia & Analgesia 2024, 139: 366-374. PMID: 38335145, PMCID: PMC11250935, DOI: 10.1213/ane.0000000000006869.
- A single item screen for clinically significant insomnia symptoms in community‐living older adultsWebster L, Hobbs J, Farhadian S, Gill T, Miner B. A single item screen for clinically significant insomnia symptoms in community‐living older adults. Journal Of The American Geriatrics Society 2024, 72: 3604-3606. PMID: 39007457, PMCID: PMC11560724, DOI: 10.1111/jgs.19086.