2021
Coxiella burnetii encodes an LvgA‐related protein important for intracellular replication
Steiner S, Meir A, Roy CR. Coxiella burnetii encodes an LvgA‐related protein important for intracellular replication. Cellular Microbiology 2021, 23: e13331. PMID: 33774901, DOI: 10.1111/cmi.13331.Peer-Reviewed Original ResearchMeSH KeywordsBacterial ProteinsCoxiella burnetiiDNA ReplicationGene Expression Regulation, BacterialHeLa CellsHost-Pathogen InteractionsHumansLegionella pneumophilaPhenotypeVacuolesVirulence FactorsConceptsIntracellular replicationDot/Icm type IVB secretion systemType IVB secretion systemDot/Icm apparatusHost cell cytosolTransposon mutagenesis screenAutophagy protein LC3Lysosome-derived organellesL. pneumophilaSecondary structure predictionChaperone complexBiogenesis defectsEffector proteinsEffector translocationProtein complexesMutagenesis screenSecretion systemLvgACell cytosolNine Mile phase IIProtein LC3MutantsReplication phenotypeProteinStructure prediction
2009
Second messenger signalling governs Escherichia coli biofilm induction upon ribosomal stress
Boehm A, Steiner S, Zaehringer F, Casanova A, Hamburger F, Ritz D, Keck W, Ackermann M, Schirmer T, Jenal U. Second messenger signalling governs Escherichia coli biofilm induction upon ribosomal stress. Molecular Microbiology 2009, 72: 1500-1516. PMID: 19460094, DOI: 10.1111/j.1365-2958.2009.06739.x.Peer-Reviewed Original ResearchMeSH KeywordsAdhesins, BacterialAnti-Bacterial AgentsBeta-GlucansBiofilmsCyclic GMPEscherichia coliEscherichia coli ProteinsGene Expression Regulation, BacterialGuanosine TetraphosphatePhosphorus-Oxygen LyasesProtein BiosynthesisPyrophosphatasesRibosomesRNA Processing, Post-TranscriptionalSecond Messenger SystemsConceptsBiofilm inductionRibosome-targeting antibioticsNovel regulatory mechanismSecond messenger signalingSpecific derepressionBiosynthesis machineryRibosomal stressTranslational stressTranslation inhibitorsPpGpp levelsExposure of bacteriaMicrobial cellsRegulatory mechanismsAdhesin productionPolysaccharide adhesinBiofilm formationPpGppImportant synergistic roleMaximal inductionBiofilm controlMachineryBiofilm modelInductionGMPSubinhibitory concentrations