Pradeep Kumar
Associate Research Scientist in Microbial PathogenesisCards
Appointments
Microbial Pathogenesis
Primary
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Titles
Associate Research Scientist in Microbial Pathogenesis
Appointments
Microbial Pathogenesis
Associate Research ScientistPrimary
Other Departments & Organizations
- Microbial Pathogenesis
Research
Research at a Glance
Yale Co-Authors
Frequent collaborators of Pradeep Kumar's published research.
Euisoon Park
Joerg Bewersdorf, PhD
John MacMicking, PhD
Publications
2024
Native architecture of a human GBP1 defense complex for cell-autonomous immunity to infection
Zhu S, Bradfield C, Maminska A, Park E, Kim B, Kumar P, Huang S, Kim M, Zhang Y, Bewersdorf J, MacMicking J. Native architecture of a human GBP1 defense complex for cell-autonomous immunity to infection. Science 2024, 383: eabm9903. PMID: 38422126, DOI: 10.1126/science.abm9903.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsGuanylate-binding proteinsCaspase-4Surface of Gram-negative bacteriaGuanosine triphosphate hydrolysisImmunity to infectionInnate immunity to infectionCryo-electron tomographyGram-negative bacteriaImmunity proteinSignaling platformsMembrane insertionHuman cellsNative structureCombat infectionsLipopolysaccharide releaseGasdermin DExtended conformationLiving organismsProteinDefense complexCellsNative architectureGBP1BacteriaInfection
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