Publications
2023
- Temsavir blocks the immunomodulatory activities of HIV-1 soluble gp120.Richard J, Prévost J, Bourassa C, Brassard N, Boutin M, Benlarbi M, Goyette G, Medjahed H, Gendron-Lepage G, Gaudette F, Chen HC, Tolbert WD, Smith AB 3rd, Pazgier M, Dubé M, Clark A, Mothes W, Kaufmann DE, Finzi A. Cell Chem Biol. 2023 Mar 17; 2023 Mar 17. PMID: 36958337.
- Bacteria require phase separation for fitness in the mammalian gut.Krypotou E, Townsend GE, Gao X, Tachiyama S, Liu J, Pokorzynski ND, Goodman AL, Groisman EA. Science. 2023 Mar 17; 2023 Mar 16. PMID: 36927025.
- The Coxiella burnetii effector EmcB is a deubiquitinase that inhibits RIG-I signaling.Duncan-Lowey J, Crabill E, Jarret A, Reed SCO, Roy CR. Proc Natl Acad Sci U S A. 2023 Mar 14; 2023 Mar 9. PMID: 36893270.
- Positive-strand RNA viruses-a Keystone Symposia report.Cable J, Denison MR, Kielian M, Jackson WT, Bartenschlager R, Ahola T, Mukhopadhyay S, Fremont DH, Kuhn RJ, Shannon A, Frazier MN, Yuen KY, Coyne CB, Wolthers KC, Ming GL, Guenther CS, Moshiri J, Best SM, Schoggins JW, Jurado KA, Ebel GD, Schäfer A, Ng LFP, Kikkert M, Sette A, Harris E, Wing PAC, Eggenberger J, Krishnamurthy SR, Mah MG, Meganck RM, Chung D, Maurer-Stroh S, Andino R, Korber B, Perlman S, Shi PY, Bárcena M, Aicher SM, Vu MN, Kenney DJ, Lindenbach BD, Nishida Y, Rénia L, Williams EP. Ann N Y Acad Sci. 2023 Mar; 2023 Jan 25. PMID: 36697369.
- Syntaxin 11 Contributes to the Interferon-Inducible Restriction of Coxiella burnetii Intracellular Infection.Ganesan S, Alvarez NN, Steiner S, Fowler KM, Corona AK, Roy CR. mBio. 2023 Feb 28; 2023 Feb 2. PMID: 36728431.
- Anti-σ(28) Factor FlgM Regulates Flagellin Gene Expression and Flagellar Polarity of Treponema denticola.Kurniyati K, Chang Y, Guo W, Liu J, Malkowski MG, Li C. J Bacteriol. 2023 Feb 22; 2023 Jan 30. PMID: 36715541.
- Molecular basis for antiviral activity of two pediatric neutralizing antibodies targeting SARS-CoV-2 Spike RBD.Chen Y, Prévost J, Ullah I, Romero H, Lisi V, Tolbert WD, Grover JR, Ding S, Gong SY, Beaudoin-Bussières G, Gasser R, Benlarbi M, Vézina D, Anand SP, Chatterjee D, Goyette G, Grunst MW, Yang Z, Bo Y, Zhou F, Béland K, Bai X, Zeher AR, Huang RK, Nguyen DN, Sherburn R, Wu D, Piszczek G, Paré B, Matthies D, Xia D, Richard J, Kumar P, Mothes W, Côté M, Uchil PD, Lavallée VP, Smith MA, Pazgier M, Haddad E, Finzi A. iScience. 2023 Jan 20; 2022 Dec 9. PMID: 36514310.
- The Fc-effector function of COVID-19 convalescent plasma contributes to SARS-CoV-2 treatment efficacy in mice.Ullah I, Beaudoin-Bussières G, Symmes K, Cloutier M, Ducas E, Tauzin A, Laumaea A, Grunst MW, Dionne K, Richard J, Bégin P, Mothes W, Kumar P, Bazin R, Finzi A, Uchil PD. Cell Rep Med. 2023 Jan 17; 2022 Dec 29. PMID: 36584683.
- Gut colonization by Bacteroides requires translation by an EF-G paralog lacking GTPase activity.Han W, Peng BZ, Wang C, Townsend GE 2nd, Barry NA, Peske F, Goodman AL, Liu J, Rodnina MV, Groisman EA. EMBO J. 2023 Jan 16; 2022 Dec 6. PMID: 36472247.
2022
- Assembly and architecture of the type III secretion sorting platform.Soto JE, Galán JE, Lara-Tejero M. Proc Natl Acad Sci U S A. 2022 Dec 20; 2022 Dec 13. PMID: 36512499.
- Interferon opens up: HIV-induced inflammation reconfigures 3D chromatin conformation and affects where HIV integrates.Wei Y, Ho YC. Mol Cell. 2022 Dec 15. PMID: 36525953.
- Rewiring the logic board of IFN signaling.MacMicking JD. Sci Signal. 2022 Dec 13; 2022 Dec 13. PMID: 36512642.
- An essential periplasmic protein coordinates lipid trafficking and is required for asymmetric polar growth in mycobacteria.Gupta KR, Gwin CM, Rahlwes KC, Biegas KJ, Wang C, Park JH, Liu J, Swarts BM, Morita YS, Rego EH. Elife. 2022 Nov 8; 2022 Nov 8. PMID: 36346214.
- Cryo-EM structures of prefusion SIV envelope trimer.Gorman J, Wang C, Mason RD, Nazzari AF, Welles HC, Zhou T, Bess JW Jr, Bylund T, Lee M, Tsybovsky Y, Verardi R, Wang S, Yang Y, Zhang B, Rawi R, Keele BF, Lifson JD, Liu J, Roederer M, Kwong PD. Nat Struct Mol Biol. 2022 Nov; 2022 Nov 7. PMID: 36344847.
- Developmental Transitions Coordinate Assembly of the Coxiella burnetii Dot/Icm Type IV Secretion System.Park D, Steiner S, Shao M, Roy CR, Liu J. Infect Immun. 2022 Oct 20; 2022 Oct 3. PMID: 36190257.
- A Tripartite Efflux System Affects Flagellum Stability in Helicobacter pylori.Gibson K, Chu JK, Zhu S, Nguyen D, Mrázek J, Liu J, Hoover TR. Int J Mol Sci. 2022 Oct 1; 2022 Oct 1. PMID: 36232924.
- Editorial: Biological rotary nanomotors.Manson MD, Nan B, Lele PP, Liu J, Duncan TM. Front Microbiol. 2022; 2022 Sep 21. PMID: 36212881.
- Identification and Characterization of the Alternative σ(28) Factor in Treponema denticola.Kurniyati K, Chang Y, Liu J, Li C. J Bacteriol. 2022 Sep 20; 2022 Aug 31. PMID: 36043861.
- Transcriptome of Epibiont Saccharibacteria Nanosynbacter lyticus Strain TM7x During the Establishment of Symbiosis.Hendrickson EL, Bor B, Kerns KA, Lamont EI, Chang Y, Liu J, Cen L, Schulte F, Hardt M, Shi W, He X, McLean JS. J Bacteriol. 2022 Sep 20; 2022 Aug 17. PMID: 35975994.
- Transcriptional and functional characterizations of multiple flagellin genes in spirochetes.Kurniyati K, Chang Y, Liu J, Li C. Mol Microbiol. 2022 Sep; 2022 Jul 18. PMID: 35776658.
- Engineered ACE2-Fc counters murine lethal SARS-CoV-2 infection through direct neutralization and Fc-effector activities.Chen Y, Sun L, Ullah I, Beaudoin-Bussières G, Anand SP, Hederman AP, Tolbert WD, Sherburn R, Nguyen DN, Marchitto L, Ding S, Wu D, Luo Y, Gottumukkala S, Moran S, Kumar P, Piszczek G, Mothes W, Ackerman ME, Finzi A, Uchil PD, Gonzalez FJ, Pazgier M. Sci Adv. 2022 Jul 15; 2022 Jul 13. PMID: 35857504.
- VE607 stabilizes SARS-CoV-2 Spike in the "RBD-up" conformation and inhibits viral entry.Ding S, Ullah I, Gong SY, Grover JR, Mohammadi M, Chen Y, Vézina D, Beaudoin-Bussières G, Verma VT, Goyette G, Gaudette F, Richard J, Yang D, Smith AB 3rd, Pazgier M, Côté M, Abrams C, Kumar P, Mothes W, Uchil PD, Finzi A, Baron C. iScience. 2022 Jul 15; 2022 Jun 3. PMID: 35677392.
- Inhibition of a Chromatin and Transcription Modulator, SLTM, Increases HIV-1 Reactivation Identified by a CRISPR Inhibition Screen.Pedersen SF, Collora JA, Kim RN, Yang K, Razmi A, Catalano AA, Yeh YJ, Mounzer K, Tebas P, Montaner LJ, Ho YC. J Virol. 2022 Jul 13; 2022 Jun 22. PMID: 35730977.
- Increasing the resilience of plant immunity to a warming climate.Kim JH, Castroverde CDM, Huang S, Li C, Hilleary R, Seroka A, Sohrabi R, Medina-Yerena D, Huot B, Wang J, Nomura K, Marr SK, Wildermuth MC, Chen T, MacMicking JD, He SY. Nature. 2022 Jul; 2022 Jun 29. PMID: 35768511.
- Mycobacterial serine/threonine phosphatase PstP is phosphoregulated and localized to mediate control of cell wall metabolism.Shamma F, Rego EH, Boutte CC. Mol Microbiol. 2022 Jul; 2022 Jun 20. PMID: 35670057.
- Cell Wall Damage Reveals Spatial Flexibility in Peptidoglycan Synthesis and a Nonredundant Role for RodA in Mycobacteria.Melzer ES, Kado T, García-Heredia A, Gupta KR, Meniche X, Morita YS, Sassetti CM, Rego EH, Siegrist MS. J Bacteriol. 2022 Jun 21; 2022 May 11. PMID: 35543537.
- Single-cell multiomics reveals persistence of HIV-1 in expanded cytotoxic T cell clones.Collora JA, Liu R, Pinto-Santini D, Ravindra N, Ganoza C, Lama JR, Alfaro R, Chiarella J, Spudich S, Mounzer K, Tebas P, Montaner LJ, van Dijk D, Duerr A, Ho YC. Immunity. 2022 Jun 14; 2022 Mar 22. PMID: 35320704.
- The Bacterial Flagellar Motor: Insights Into Torque Generation, Rotational Switching, and Mechanosensing.Guo S, Liu J. Front Microbiol. 2022; 2022 May 30. PMID: 35711788.
- Typhoid toxin sorting and exocytic transport from Salmonella Typhi-infected cells.Chang SJ, Hsu YT, Chen Y, Lin YY, Lara-Tejero M, Galan JE. Elife. 2022 May 17; 2022 May 17. PMID: 35579416.
- Cancer Microbiology.DiMaio D, Emu B, Goodman AL, Mothes W, Justice A. J Natl Cancer Inst. 2022 May 9. PMID: 34850062.
- The In Vivo and In Vitro Architecture of the Hepatitis C Virus RNA Genome Uncovers Functional RNA Secondary and Tertiary Structures.Wan H, Adams RL, Lindenbach BD, Pyle AM. J Virol. 2022 Apr 27; 2022 Mar 30. PMID: 35353000.
- Gut Commensal Bacteroidetes Encode a Novel Class of Vitamin B(12)-Binding Proteins.Putnam EE, Abellon-Ruiz J, Killinger BJ, Rosnow JJ, Wexler AG, Folta-Stogniew E, Wright AT, van den Berg B, Goodman AL. mBio. 2022 Apr 26; 2022 Mar 1. PMID: 35227073.
- Spindle-shaped archaeal viruses evolved from rod-shaped ancestors to package a larger genome.Wang F, Cvirkaite-Krupovic V, Vos M, Beltran LC, Kreutzberger MAB, Winter JM, Su Z, Liu J, Schouten S, Krupovic M, Egelman EH. Cell. 2022 Apr 14; 2022 Mar 23. PMID: 35325592.
- TCR-mimic bispecific antibodies to target the HIV-1 reservoir.Sengupta S, Board NL, Wu F, Moskovljevic M, Douglass J, Zhang J, Reinhold BR, Duke-Cohan J, Yu J, Reed MC, Tabdili Y, Azurmendi A, Fray EJ, Zhang H, Hsiue EH, Jenike K, Ho YC, Gabelli SB, Kinzler KW, Vogelstein B, Zhou S, Siliciano JD, Sadegh-Nasseri S, Reinherz EL, Siliciano RF. Proc Natl Acad Sci U S A. 2022 Apr 12; 2022 Apr 8. PMID: 35394875.
- Antigenic analysis of the HIV-1 envelope trimer implies small differences between structural states 1 and 2.Cale EM, Driscoll JI, Lee M, Gorman J, Zhou T, Lu M, Geng H, Lai YT, Chuang GY, Doria-Rose NA, Mothes W, Kwong PD, Mascola JR. J Biol Chem. 2022 Apr; 2022 Mar 10. PMID: 35283191.
- FliL ring enhances the function of periplasmic flagella.Guo S, Xu H, Chang Y, Motaleb MA, Liu J. Proc Natl Acad Sci U S A. 2022 Mar 15; 2022 Mar 7. PMID: 35254893.
- A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection.Beaudoin-Bussières G, Chen Y, Ullah I, Prévost J, Tolbert WD, Symmes K, Ding S, Benlarbi M, Gong SY, Tauzin A, Gasser R, Chatterjee D, Vézina D, Goyette G, Richard J, Zhou F, Stamatatos L, McGuire AT, Charest H, Roger M, Pozharski E, Kumar P, Mothes W, Uchil PD, Pazgier M, Finzi A. Cell Rep. 2022 Feb 15; 2022 Jan 25. PMID: 35123652.
- Proteins DotY and DotZ modulate the dynamics and localization of the type IVB coupling complex of Legionella pneumophila.Macé K, Meir A, Lukoyanova N, Liu L, Chetrit D, Hospenthal MK, Roy CR, Waksman G. Mol Microbiol. 2022 Feb; 2021 Dec 6. PMID: 34816517.
- The flagellar motor protein FliL forms a scaffold of circumferentially positioned rings required for stator activation.Tachiyama S, Chan KL, Liu X, Hathroubi S, Peterson B, Khan MF, Ottemann KM, Liu J, Roujeinikova A. Proc Natl Acad Sci U S A. 2022 Jan 25. PMID: 35046042.
- The loud minority: Transcriptionally active HIV-1-infected cells survive, proliferate, and persist.Collora JA, Ho YC. Cell. 2022 Jan 20. PMID: 35063069.
- Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern.Li W, Chen Y, Prévost J, Ullah I, Lu M, Gong SY, Tauzin A, Gasser R, Vézina D, Anand SP, Goyette G, Chaterjee D, Ding S, Tolbert WD, Grunst MW, Bo Y, Zhang S, Richard J, Zhou F, Huang RK, Esser L, Zeher A, Côté M, Kumar P, Sodroski J, Xia D, Uchil PD, Pazgier M, Finzi A, Mothes W. Cell Rep. 2022 Jan 11; 2021 Dec 15. PMID: 34971573.
- Reinventing positive-strand RNA virus reverse genetics.Lindenbach BD. Adv Virus Res. 2022; 2022 Mar 29. PMID: 35840179.
2021
- Characterization of the Flagellar Collar Reveals Structural Plasticity Essential for Spirochete Motility.Chang Y, Xu H, Motaleb MA, Liu J. mBio. 2021 Dec 21; 2021 Nov 23. PMID: 34809456.
- A multidimensional HIV-1 persistence model for clonal expansion and viral rebound in vitro.Eshetu A, Ho YC. Cell Rep Methods. 2021 Dec 20; 2021 Dec 20. PMID: 35475216.
- Design and implementation of a cohort study of persons living with HIV infection who are initiating medication treatment for opioid use disorder to evaluate HIV-1 persistence.Schultheis A, Sanchez M, Pedersen S, Kyriakides T, Ho YC, Kluger Y, Springer SA. Contemp Clin Trials Commun. 2021 Dec; 2021 Nov 11. PMID: 34825103.
- Engineered ACE2-Fc counters murine lethal SARS-CoV-2 infection through direct neutralization and Fc-effector activities.Chen Y, Sun L, Ullah I, Beaudoin-Bussières G, Anand SP, Hederman AP, Tolbert WD, Sherburn R, Nguyen DN, Marchitto L, Ding S, Wu D, Luo Y, Gottumukkala S, Moran S, Kumar P, Piszczek G, Mothes W, Ackerman ME, Finzi A, Uchil PD, Gonzalez FJ, Pazgier M. bioRxiv. 2021 Nov 24; 2021 Nov 24. PMID: 34845451.
- The Legionella pneumophila Effector RavY Contributes to a Replication-Permissive Vacuolar Environment during Infection.Liu L, Roy CR. Infect Immun. 2021 Nov 16; 2021 Sep 20. PMID: 34543123.
- Cryo-EM structure of the needle filament tip complex of the Salmonella type III secretion injectisome.Guo EZ, Galán JE. Proc Natl Acad Sci U S A. 2021 Nov 2. PMID: 34706941.
- Role of the major determinant of polar flagellation FlhG in the endoflagella-containing spirochete Leptospira.Fule L, Halifa R, Fontana C, Sismeiro O, Legendre R, Varet H, Coppée JY, Murray GL, Adler B, Hendrixson DR, Buschiazzo A, Guo S, Liu J, Picardeau M. Mol Microbiol. 2021 Nov; 2021 Oct 30. PMID: 34657338.
- Salmonella Typhimurium and inflammation: a pathogen-centric affair.Galán JE. Nat Rev Microbiol. 2021 Nov; 2021 May 19. PMID: 34012042.
- Structural basis of bacterial flagellar motor rotation and switching.Chang Y, Carroll BL, Liu J. Trends Microbiol. 2021 Nov; 2021 Apr 14. PMID: 33865677.
- BB0259 Encompasses a Peptidoglycan Lytic Enzyme Function for Proper Assembly of Periplasmic Flagella in Borrelia burgdorferi.Xu H, Hu B, Flesher DA, Liu J, Motaleb MA. Front Microbiol. 2021; 2021 Oct 1. PMID: 34659138.
- Impact of temperature on the affinity of SARS-CoV-2 Spike glycoprotein for host ACE2.Prévost J, Richard J, Gasser R, Ding S, Fage C, Anand SP, Adam D, Gupta Vergara N, Tauzin A, Benlarbi M, Gong SY, Goyette G, Privé A, Moreira S, Charest H, Roger M, Mothes W, Pazgier M, Brochiero E, Boivin G, Abrams CF, Schön A, Finzi A. J Biol Chem. 2021 Oct; 2021 Aug 31. PMID: 34478710.
- The Clonal Expansion Dynamics of the HIV-1 Reservoir: Mechanisms of Integration Site-Dependent Proliferation and HIV-1 Persistence.Yeh YJ, Yang K, Razmi A, Ho YC. Viruses. 2021 Sep 17; 2021 Sep 17. PMID: 34578439.
- Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacy.Ullah I, Prévost J, Ladinsky MS, Stone H, Lu M, Anand SP, Beaudoin-Bussières G, Symmes K, Benlarbi M, Ding S, Gasser R, Fink C, Chen Y, Tauzin A, Goyette G, Bourassa C, Medjahed H, Mack M, Chung K, Wilen CB, Dekaban GA, Dikeakos JD, Bruce EA, Kaufmann DE, Stamatatos L, McGuire AT, Richard J, Pazgier M, Bjorkman PJ, Mothes W, Finzi A, Kumar P, Uchil PD. Immunity. 2021 Sep 14; 2021 Aug 18. PMID: 34453881.
- A Common Pathway for Activation of Host-Targeting and Bacteria-Targeting Toxins in Human Intestinal Bacteria.Bao Y, Verdegaal AA, Anderson BW, Barry NA, He J, Gao X, Goodman AL. mBio. 2021 Aug 31; 2021 Aug 31. PMID: 34465018.
- Optimization of Triarylpyridinone Inhibitors of the Main Protease of SARS-CoV-2 to Low-Nanomolar Antiviral Potency.Zhang CH, Spasov KA, Reilly RA, Hollander K, Stone EA, Ippolito JA, Liosi ME, Deshmukh MG, Tirado-Rives J, Zhang S, Liang Z, Miller SJ, Isaacs F, Lindenbach BD, Anderson KS, Jorgensen WL. ACS Med Chem Lett. 2021 Aug 12; 2021 Jul 14. PMID: 34408808.
- Structural Basis and Mode of Action for Two Broadly Neutralizing Antibodies Against SARS-CoV-2 Emerging Variants of Concern.Li W, Chen Y, Prévost J, Ullah I, Lu M, Gong SY, Tauzin A, Gasser R, Vézina D, Anand SP, Goyette G, Chaterjee D, Ding S, Tolbert WD, Grunst MW, Bo Y, Zhang S, Richard J, Zhou F, Huang RK, Esser L, Zeher A, Côté M, Kumar P, Sodroski J, Xia D, Uchil PD, Pazgier M, Finzi A, Mothes W. bioRxiv. 2021 Aug 3; 2021 Aug 3. PMID: 34373853.
- A human apolipoprotein L with detergent-like activity kills intracellular pathogens.Gaudet RG, Zhu S, Halder A, Kim BH, Bradfield CJ, Huang S, Xu D, Mamiñska A, Nguyen TN, Lazarou M, Karatekin E, Gupta K, MacMicking JD. Science. 2021 Jul 16. PMID: 34437126.
- A single dose of the SARS-CoV-2 vaccine BNT162b2 elicits Fc-mediated antibody effector functions and T cell responses.Tauzin A, Nayrac M, Benlarbi M, Gong SY, Gasser R, Beaudoin-Bussières G, Brassard N, Laumaea A, Vézina D, Prévost J, Anand SP, Bourassa C, Gendron-Lepage G, Medjahed H, Goyette G, Niessl J, Tastet O, Gokool L, Morrisseau C, Arlotto P, Stamatatos L, McGuire AT, Larochelle C, Uchil P, Lu M, Mothes W, De Serres G, Moreira S, Roger M, Richard J, Martel-Laferrière V, Duerr R, Tremblay C, Kaufmann DE, Finzi A. Cell Host Microbe. 2021 Jul 14; 2021 Jun 4. PMID: 34133950.
- Interconnecting solvent quality, transcription, and chromosome folding in Escherichia coli.Xiang Y, Surovtsev IV, Chang Y, Govers SK, Parry BR, Liu J, Jacobs-Wagner C. Cell. 2021 Jul 8; 2021 Jun 28. PMID: 34186018.
- In vivo imaging of retrovirus infection reveals a role for Siglec-1/CD169 in multiple routes of transmission.Haugh KA, Ladinsky MS, Ullah I, Stone HM, Pi R, Gilardet A, Grunst MW, Kumar P, Bjorkman PJ, Mothes W, Uchil PD. Elife. 2021 Jul 5; 2021 Jul 5. PMID: 34223819.
- Restriction of SARS-CoV-2 replication by targeting programmed -1 ribosomal frameshifting.Sun Y, Abriola L, Niederer RO, Pedersen SF, Alfajaro MM, Silva Monteiro V, Wilen CB, Ho YC, Gilbert WV, Surovtseva YV, Lindenbach BD, Guo JU. Proc Natl Acad Sci U S A. 2021 Jun 29. PMID: 34185680.
- Composition and Biophysical Properties of the Sorting Platform Pods in the Shigella Type III Secretion System.Tachiyama S, Skaar R, Chang Y, Carroll BL, Muthuramalingam M, Whittier SK, Barta ML, Picking WL, Liu J, Picking WD. Front Cell Infect Microbiol. 2021; 2021 Jun 3. PMID: 34150677.
- A phase-separated nuclear GBPL circuit controls immunity in plants.Huang S, Zhu S, Kumar P, MacMicking JD. Nature. 2021 Jun; 2021 May 26. PMID: 34040255.
- Coxiella burnetii encodes an LvgA-related protein important for intracellular replication.Steiner S, Meir A, Roy CR. Cell Microbiol. 2021 Jun; 2021 Apr 22. PMID: 33774901.
- The peptidoglycan-associated protein NapA plays an important role in the envelope integrity and in the pathogenesis of the lyme disease spirochete.Davis MM, Brock AM, DeHart TG, Boribong BP, Lee K, McClune ME, Chang Y, Cramer N, Liu J, Jones CN, Jutras BL. PLoS Pathog. 2021 May; 2021 May 13. PMID: 33984073.
- The Salmonella effector protein SopD targets Rab8 to positively and negatively modulate the inflammatory response.Lian H, Jiang K, Tong M, Chen Z, Liu X, Galán JE, Gao X. Nat Microbiol. 2021 May; 2021 Feb 18. PMID: 33603205.
- Measuring the size and decay dynamics of the HIV-1 latent reservoir.Liu R, Catalano AA, Ho YC. Cell Rep Med. 2021 Apr 20; 2021 Apr 20. PMID: 33948579.
- Shock-and-kill versus block-and-lock: Targeting the fluctuating and heterogeneous HIV-1 gene expression.Yeh YJ, Ho YC. Proc Natl Acad Sci U S A. 2021 Apr 20. PMID: 33758027.
- Fighting microbial pathogens by integrating host ecosystem interactions and evolution.Burmeister AR, Hansen E, Cunningham JJ, Rego EH, Turner PE, Weitz JS, Hochberg ME. Bioessays. 2021 Mar; 2020 Dec 30. PMID: 33377530.
- A CRISPR interference platform for selective downregulation of gene expression in Borrelia burgdorferi.Takacs CN, Scott M, Chang Y, Kloos ZA, Irnov I, Rosa PA, Liu J, Jacobs-Wagner C. Appl Environ Microbiol. 2021 Mar 1; 2020 Nov 30. PMID: 33257311.
- A mammalian system for high-resolution imaging of intact cells by cryo-electron tomography.Li X, Park D, Chang Y, Radhakrishnan A, Wu H, Wang P, Liu J. Prog Biophys Mol Biol. 2021 Mar; 2020 Oct 13. PMID: 33058942.
- SARS-CoV-2 Variants Increase Kinetic Stability of Open Spike Conformations as an Evolutionary Strategy.Yang Z, Han Y, Ding S, Shi W, Zhou T, Finzi A, Kwong PD, Mothes W, Lu M. mBio. 2021 Feb 22; 2022 Feb 15. PMID: 35164561.
- The XPB Subunit of the TFIIH Complex Plays a Critical Role in HIV-1 Transcription and XPB Inhibition by Spironolactone Prevents HIV-1 Reactivation from Latency.Mori L, Jenike K, Yeh YJ, Lacombe B, Li C, Getzler A, Mediouni S, Cameron M, Pipkin M, Ho YC, Ramirez BC, Valente S. J Virol. 2021 Feb 15; 2020 Nov 25. PMID: 33239456.
- Symmetrical arrangement of proteins under release-ready vesicles in presynaptic terminals.Radhakrishnan A, Li X, Grushin K, Krishnakumar SS, Liu J, Rothman JE. Proc Natl Acad Sci U S A. 2021 Feb 2. PMID: 33468631.
- Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection.Wei J, Alfajaro MM, DeWeirdt PC, Hanna RE, Lu-Culligan WJ, Cai WL, Strine MS, Zhang SM, Graziano VR, Schmitz CO, Chen JS, Mankowski MC, Filler RB, Ravindra NG, Gasque V, de Miguel FJ, Patil A, Chen H, Oguntuyo KY, Abriola L, Surovtseva YV, Orchard RC, Lee B, Lindenbach BD, Politi K, van Dijk D, Kadoch C, Simon MD, Yan Q, Doench JG, Wilen CB. Cell. 2021 Jan 7; 2020 Oct 20. PMID: 33147444.
- The single-cell landscape of immunological responses of CD4+ T cells in HIV versus severe acute respiratory syndrome coronavirus 2.Collora JA, Liu R, Albrecht K, Ho YC. Curr Opin HIV AIDS. 2021 Jan. PMID: 33165008.
2020
- The conserved translation factor LepA is required for optimal synthesis of a porin family in Mycobacterium smegmatis.Fishbein SRS, Tomasi FG, Wolf ID, Dulberger CL, Wang A, Keshishian H, Wallace L, Carr SA, Ioerger TR, Rego EH, Rubin EJ. J Bacteriol. 2020 Dec 23; 2020 Dec 23. PMID: 33361193.
- Real-Time Conformational Dynamics of SARS-CoV-2 Spikes on Virus Particles.Lu M, Uchil PD, Li W, Zheng D, Terry DS, Gorman J, Shi W, Zhang B, Zhou T, Ding S, Gasser R, Prévost J, Beaudoin-Bussières G, Anand SP, Laumaea A, Grover JR, Liu L, Ho DD, Mascola JR, Finzi A, Kwong PD, Blanchard SC, Mothes W. Cell Host Microbe. 2020 Dec 9; 2020 Nov 13. PMID: 33242391.
- Molecular mechanism for rotational switching of the bacterial flagellar motor.Chang Y, Zhang K, Carroll BL, Zhao X, Charon NW, Norris SJ, Motaleb MA, Li C, Liu J. Nat Struct Mol Biol. 2020 Nov; 2020 Sep 7. PMID: 32895555.
- Structural Conservation and Adaptation of the Bacterial Flagella Motor.Carroll BL, Liu J. Biomolecules. 2020 Oct 29; 2020 Oct 29. PMID: 33138111.
- Correction for Lu et al., "Shedding-Resistant HIV-1 Envelope Glycoproteins Adopt Downstream Conformations That Remain Responsive to Conformation-Preferring Ligands".Lu M, Ma X, Reichard N, Terry DS, Arthos J, Smith AB 3rd, Sodroski JG, Blanchard SC, Mothes W. J Virol. 2020 Oct 27; 2020 Oct 27. PMID: 33109770.
- Restriction of SARS-CoV-2 Replication by Targeting Programmed -1 Ribosomal Frameshifting In Vitro.Sun Y, Abriola L, Surovtseva YV, Lindenbach BD, Guo JU. bioRxiv. 2020 Oct 21; 2020 Oct 21. PMID: 33106809.
- SV40 Polyomavirus Activates the Ras-MAPK Signaling Pathway for Vacuolization, Cell Death, and Virus Release.Motamedi N, Sewald X, Luo Y, Mothes W, DiMaio D. Viruses. 2020 Oct 5; 2020 Oct 5. PMID: 33028008.
- Generation and Characterization of Typhoid Toxin-Neutralizing Human Monoclonal Antibodies.Jiao X, Smith S, Stack G, Liang Q, Bradley A, Kellam P, Galán JE. Infect Immun. 2020 Sep 18; 2020 Sep 18. PMID: 32661121.
- The flagellar motor of Vibrio alginolyticus undergoes major structural remodeling during rotational switching.Carroll BL, Nishikino T, Guo W, Zhu S, Kojima S, Homma M, Liu J. Elife. 2020 Sep 7; 2020 Sep 7. PMID: 32893817.
- Filgotinib suppresses HIV-1-driven gene transcription by inhibiting HIV-1 splicing and T cell activation.Yeh YJ, Jenike KM, Calvi RM, Chiarella J, Hoh R, Deeks SG, Ho YC. J Clin Invest. 2020 Sep 1. PMID: 32573496.
- A decade of advances in transposon-insertion sequencing.Cain AK, Barquist L, Goodman AL, Paulsen IT, Parkhill J, van Opijnen T. Nat Rev Genet. 2020 Sep; 2020 Jun 12. PMID: 32533119.
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