Associate Professor of Chemistry and Associate Professor of Microbial Pathogenesis
Microbiome Research at Yale
The microbiota (the collection of bacteria, archaea, eukaryotes, and viruses that live in or on a host organism) impacts many aspects of human and environmental health. Labs at Yale University explore these relationships using a wide range of systems and tools.
These groups belong to many departments and interact through research seminars, graduate student advising, and collaboration.
To be added to this page, please contact Andrew Goodman.
Faculty and Labs
- The Crawford group decodes orphan bacterial biosynthetic gene clusters in bacteria-insect and bacteria-human associations.
Waldemar Von Zedtwitz Professor of Medicine (Infectious Diseases) and Professor of Epidemiology (Microbial Diseases) and of Microbial Pathogenesis; Affiliated Faculty, Yale Institute for Global Health; Section Chief, Infectious Diseases
We study how the microbiota of ticks and mosquitoes influences the transmission of arthropod-borne diseases.Sterling Professor of Immunobiology; Investigator, Howard Hughes Medical Institute
The Flavell lab studies the relationship between the microbiota and the immune system, particularly in the context of human diseases such as IBD, metabolic syndrome and cancer and their mouse models.Lucille P. Markey Professor of Microbial Pathogenesis and Professor of Cell Biology; Chair, Microbial Pathogenesis
Mechanisms of enteric pathogen restriction by the gut microbiota.Professor of Medicine (Digestive Diseases); Chief, Digestive Diseases, VA-CT Healthcare System
Microbiome research in experimental cirrhosis to identify measures to decrease bacterial translocation, a mechanism that leads to systemic inflammation and decompensation in patients with cirrhosis.C.N.H. Long Professor of Microbial Pathogenesis and Director of Microbial Sciences Institute
Cooperation and competition in the human gut microbiome; role of the gut microbiota in drug metabolism and function.Waldemar Von Zedtwitz Professor of Microbial Pathogenesis
Our laboratory investigates gene control in Bacteroides thetaiotaomicron, a dominant member of the mammalian gut microbiota.William S. and Lois Stiles Edgerly Professor of Neurology and Professor of Immunobiology; Chair, Neurology; Neurologist-in-Chief, Yale New Haven Hospital
Our lab is investigating the interplay between human diet, microbiome, genetics, and immune reponses in inflammatory disease.Assistant Professor of Molecular, Cellular and Developmental Biology and of Chemistry
My lab applies chemical biology to the discovery of enzymes and other proteins whose biochemical activity shapes host-microbe dynamics in the context of gastrointestinal infections and the gut microbiota.C.N.H. Long Professor of Immunobiology and of Medicine (Endocrinology)
My lab is interested in looking at the effect of the microbiome on responses to biologics and in understanding how the microbiome regulates immune tolerance.Milton Harris ’29 Ph.D. Professor of Chemistry
Our research focuses on the structure elucidation and mode of action of small molecules encoded in the human microbiome. We are particularly interested in secondary microbiota metabolites that have been implicated in human cancers.Associate Professor of Molecular, Cellular and Developmental Biology
Applying synthetic biology technologies to engineer clinical and ecological microbiomes.Sterling Professor of Immunobiology and Professor of Dermatology and of Molecular, Cellular, and Developmental Biology and of Epidemiology (Microbial Diseases); Investigator, Howard Hughes Medical Institute
The Iwasaki laboratory studies the role of microbiome and virome on immunity and inflammatory diseases. Our research showed that signals from the microbiome help optimize the immune response in the respiratory tract against influenza virus infection.Assistant Professor of Epidemiology (Environmental Health Sciences)
Understanding the role of microbial metabolites in human disease.Gustavus and Louise Pfeiffer Research Foundation M.D.-Ph.D. Program Director and Professor of Medicine (Infectious Diseases) and of Microbial Pathogenesis; Professor, Microbial Pathogenesis; Director, MD-PhD Program, Yale University
Acquisition and maturation of the gut and airway microbiomes in infants with Cystic Fibrosis.Assistant Professor
The Konnikova lab is interested in how the microbiome and the associated metabolome regulate immune development and homeostasis at barrier sites.Professor of Microbial Pathogenesis
We are developing a high-throughput cryo-electron tomography (cryo-ET) pipeline for high-resolution structure determination of molecular machines in cells, in order to gain molecular insights into fundamental biochemical processes.Professor of Molecular Biophysics and Biochemistry and of Chemical and Environmental Engineering
Provenance and authentication of works of art and other forms of cultural heritage.Associate Professor Term
The Palm lab is focused on illuminating the fundamental principles that govern immune-microbiota interactions in human health and disease.Deputy Dean of Yale School of Public Health, Senior Associate Dean of Academic Affairs, and Anna M. R. Lauder Professor of Epidemiology (Microbial Diseases); Affiliated Faculty, Yale Institute for Global Health; Affiliated Faculty, Yale Institute for Global Health
The Pettigrew research lab conducts clinical epidemiologic studies of the respiratory and gastrointestinal microbiota in order to facilitate progress towards the goal of manipulating the microbiota for control of antibiotic resistance and transmission of multi-drug resistant organisms.Professor of Ecology and Evolutionary Biology, of Epidemiology (Microbial Diseases) and of Forestry And Environmental Studies
Our lab studies the microbial ecology of mosquito oviposition.Associate Professor Term
Our lab studies the evolution of public goods based microbial communities, using a combination of mathematical modeling and experiments in vitro.Rachel Carson Professor of Ecology and Evolutionary Biology
The Turner Lab is interested in the role of bacteriophages in the ecology and evolution of microbiomes, especially phage therapy approaches to targeting bacterial pathogens in/on the human body and whether such treatment affects community composition of resident phages and non-target bacteria inhabiting the microbiome.Professor of Medicine (Endocrinology); Director of Core Laboratory of Yale Center for Clinical Investigation (YCCI)
We study the role of the microbiome in the pathogenesis of type 1 diabetes and obesity, focusing on their interaction with immune cells in mouse models and humans.Assistant Professor, Molecular, Cellular and Developmental Biology
Our lab is interested in how commensal bacteria determine the outcome of infections by gut pathogens such as Vibrio cholerae, and what the role bacterial biofilm plays in the interaction between the pathogen and the resident bacteria.Ira V. Hiscock Professor of Biostatistics, Professor of Genetics and Professor of Statistics and Data Science; Affiliated Faculty, Yale Institute for Global Health
Development and application of statistical methods for the analysis of microbiome data.