2013
Src Inhibits Midline Axon Crossing Independent of Frazzled/Deleted in Colorectal Carcinoma (DCC) Receptor Tyrosine Phosphorylation
O'Donnell M, Bashaw G. Src Inhibits Midline Axon Crossing Independent of Frazzled/Deleted in Colorectal Carcinoma (DCC) Receptor Tyrosine Phosphorylation. Journal Of Neuroscience 2013, 33: 305-314. PMID: 23283343, PMCID: PMC3739878, DOI: 10.1523/jneurosci.2756-12.2013.Peer-Reviewed Original ResearchConceptsSrc kinaseMidline axonsTyrosine phosphorylationSrc family kinasesDrosophila embryonic CNSReceptor tyrosine phosphorylationCommissural axonsDrosophila orthologUnexpected functionFamily kinasesEmbryonic CNSDownstream effectorsMidline attractionNetrin receptor DCCKinaseNetrin familyNovel mechanismAttractive turningPhosphorylationEffectorsReceptor DCCOrthologsCommissural neuronsVertebratesFrazzled
2006
Functional analysis of Sox8 during neural crest development in Xenopus
O'Donnell M, Hong C, Huang X, Delnicki R, Saint-Jeannet J. Functional analysis of Sox8 during neural crest development in Xenopus. Development 2006, 133: 3817-3826. PMID: 16943273, DOI: 10.1242/dev.02558.Peer-Reviewed Original ResearchConceptsNeural crest developmentNeural crest progenitorsNeural plate borderCrest developmentNeural crest cellsCrest cellsSOX8 expressionExpression domainsPlate borderCranial crest cellsTrunk neural crest cellsMorpholino-mediated knockdownNeural crest specificationNeural crest formationMid-gastrula stageSpecies-specific differencesSox proteinsProgenitor specificationSoxE proteinsCrest formationTranscription factorsChick orthologPharyngeal archesMultiple lineagesNeural plate