Cilia structure and intraflagellar transport differentially regulate sensory response dynamics within and between C. elegans chemosensory neurons
Philbrook A, O’Donnell M, Grunenkovaite L, Sengupta P. Cilia structure and intraflagellar transport differentially regulate sensory response dynamics within and between C. elegans chemosensory neurons. PLOS Biology 2024, 22: e3002892. PMID: 39591402, PMCID: PMC11593760, DOI: 10.1371/journal.pbio.3002892.Peer-Reviewed Original ResearchConceptsIntraflagellar transportOrganization of signaling moleculesASH nociceptive neuronsAWA olfactory neuronsCiliary traffickingNociceptive neuronsCilia baseOlfactory neuronsCaenorhabditis elegansOdor responsesSignaling proteinsCilia organizationSensory neuronsCilium structurePrimary ciliaCilia structureSignaling moleculesAcute inhibitionSegregation of receptorsRegulation of responsesChemosensory neuronsNeuron typesCilium lengthNeuronal responsesEctopic branching