Keiichiro Mukai, PhD
Postdoctoral Associate (Microbial Pathogenesis)About
Research
Publications
2024
Heterologous biosynthesis of myxobacterial lanthipeptides melittapeptins.
Kaweewan I, Mukai K, Rukthanapitak P, Nakagawa H, Hosaka T, Kodani S. Heterologous biosynthesis of myxobacterial lanthipeptides melittapeptins. Appl Microbiol Biotechnol 2024, 108: 122. PMID: 38229328, DOI: 10.1007/s00253-023-12834-4.Peer-Reviewed Original Research
2023
Phenomenological interpretations of the mechanism for the concentration-dependent positive effect of antibiotic lincomycin on Streptomyces coelicolor A3(2).
Mukai K, Shibayama T, Imai Y, Hosaka T. Phenomenological interpretations of the mechanism for the concentration-dependent positive effect of antibiotic lincomycin on Streptomyces coelicolor A3(2). Appl Environ Microbiol 2023, 89: e0113323. PMID: 37732750, DOI: 10.1128/aem.01133-23.Peer-Reviewed Original ResearchHeterologous Production and Structure Determination of a New Lanthipeptide Sinosporapeptin Using a Cryptic Gene Cluster in an Actinobacterium Sinosporangium siamense.
Saito K, Mukai K, Kaweewan I, Nakagawa H, Hosaka T, Kodani S. Heterologous Production and Structure Determination of a New Lanthipeptide Sinosporapeptin Using a Cryptic Gene Cluster in an Actinobacterium Sinosporangium siamense. J Microbiol 2023, 61: 641-648. PMID: 37306831, DOI: 10.1007/s12275-023-00059-z.Peer-Reviewed Original Research
2020
Lincomycin-Induced Secondary Metabolism in Streptomyces lividans 66 with a Mutation in the Gene Encoding the RNA Polymerase Beta Subunit.
Mukai K, Kobayashi M, Hoshino K, Maruyama T, Hayashi D, Hamauzu R, Hosaka T. Lincomycin-Induced Secondary Metabolism in Streptomyces lividans 66 with a Mutation in the Gene Encoding the RNA Polymerase Beta Subunit. Curr Microbiol 2020, 77: 2933-2939. PMID: 32681314, DOI: 10.1007/s00284-020-02126-9.Peer-Reviewed Original ResearchA putative mechanism underlying secondary metabolite overproduction by Streptomyces strains with a 23S rRNA mutation conferring erythromycin resistance.
Hoshino K, Imai Y, Mukai K, Hamauzu R, Ochi K, Hosaka T. A putative mechanism underlying secondary metabolite overproduction by Streptomyces strains with a 23S rRNA mutation conferring erythromycin resistance. Appl Microbiol Biotechnol 2020, 104: 2193-2203. PMID: 31925486, DOI: 10.1007/s00253-019-10288-1.Peer-Reviewed Original Research
2018
A possible mechanism for lincomycin induction of secondary metabolism in Streptomyces coelicolor A3(2).
Ishizuka M, Imai Y, Mukai K, Shimono K, Hamauzu R, Ochi K, Hosaka T. A possible mechanism for lincomycin induction of secondary metabolism in Streptomyces coelicolor A3(2). Antonie Van Leeuwenhoek 2018, 111: 705-716. PMID: 29372424, DOI: 10.1007/s10482-018-1021-0.Peer-Reviewed Original Research
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Mailing Address
Groisman Lab
Boyer Center for Molecular Medicine, 295 Congress Avenue
New Haven, CT 06519
United States