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Research

Our research program seeks answers to a fundamental biological question: 
How does an organism know when, where and for long to turn a gene on or off?
We address this question by investigating bacterial species
that establish intimate interactions with animal hosts.
Visit our Research page and Groisman Lab News for more information.

Slow growth determines nonheritable antibiotic resistance in Salmonella enterica.
We report that persistent bacteria form as a result of slow growth alone, despite opposite changes in the abundance of proteins, metabolites, and signaling molecules. Our findings argue that transitory disturbances to core activities, which are often linked to cell growth, promote a persister state regardless of the underlying physiological process responsible for the change in growth.

Groisman receives mentorship award

Congratulations to Eduardo Groisman, who has received the 2019 Yale Postdoctoral Mentoring Award! The prize is awarded by the Yale Office for Postdoctoral Affairs and recognizes faculty who best exemplify the role of a mentor and provide exceptional mentoring to scholars. Honorees are selected based on nominations from current postdoctoral researchers throughout Yale University. Dr. Groisman is Waldemar Von Zedtwitz Professor of Microbial Pathogenesis and a member of the Yale Microbial Sciences Institute.