2005
The origin and evolution of human pathogens
Groisman EA, Casadesús J. The origin and evolution of human pathogens. Molecular Microbiology 2005, 56: 1-7. PMID: 15773974, DOI: 10.1111/j.1365-2958.2005.04564.x.Peer-Reviewed Original ResearchConceptsCreation of genesNon-host environmentsHuman pathogensRelated bacterial speciesCertain pathogensORFan genesHomologous genesCell surface modificationExpression of productsHousekeeping functionsRelated membersHost rangeColonization processTissue specificityPathogenicity islandSequence databasesCertain lociBacterial speciesGenesCell surfaceDisparate regulationGenetic originBacterial pathogensNew functionsGene variation
2004
Evolution and Ecology of Salmonella
Winfield MD, Groisman EA. Evolution and Ecology of Salmonella. EcoSal Plus 2004, 1: 10.1128/ecosalplus.6.4.6. PMID: 26443365, DOI: 10.1128/ecosalplus.6.4.6.Peer-Reviewed Original ResearchNew genetic variationWhole-genome comparisonsGenus SalmonellaWarm-blooded hostsAdaptive radiationAncestral associationGene contentSalmonella-specific genesGenetic diversityHost specificityParticular lineageNonhost environmentsGenetic variationGenetic mechanismsHost rangeDiverse ecologyWide phenotypic heterogeneityGenetic materialEcology of SalmonellaGenetic eventsWide diversityPhenotypic heterogeneityS. entericaGenusEcology
1999
Pathogenicity Islands and the Evolution of Salmonella Virulence
Groisman E, Blanc‐Potard A, Uchiya K. Pathogenicity Islands and the Evolution of Salmonella Virulence. 1999, 127-150. DOI: 10.1128/9781555818173.ch7.Peer-Reviewed Original ResearchSPI-1 genesPathogenicity islandDNA segmentsSPI-1Evolution of SalmonellaCultured epithelial cellsSalmonella-specific sequenceTRNA genesExport apparatusTranscriptional unitsLarge operonNonhost environmentsSecretion systemBacterial entryHousekeeping genesSalmonella virulenceHost rangeSPI-2Secretory systemHost cellsAspects of infectionNonphagocytic cellsGenesMacrophage apoptosisOperon
1995
The evolution off invasion by enteric bacteria
Ochman H, Groisman EA. The evolution off invasion by enteric bacteria. Canadian Journal Of Microbiology 1995, 41: 555-561. PMID: 7641138, DOI: 10.1139/m95-074.Peer-Reviewed Original ResearchConceptsPhylogenetic distributionGenomic locationPlant pathogensDivergent pathogensSecretory pathwayVirulence proteinsGene complexHost rangeHost cellsSimilar machineryEnteric bacteriaPathogensProteinDisease pathologyEnteric pathogensMachineryBacteriaPathwayShigella sppSppAnalogous structuresSequenceInvasionCellsComplexes