Victoria Fan
About
Research
Publications
2025
Delayed integration of somatostatin interneurons into visual circuits.
Wang A, Ferguson KA, Gupta J, Fan VH, Sun S, Barson D, Higley MJ, Cardin JA. Delayed integration of somatostatin interneurons into visual circuits. Nat Commun 2025, 16: 9633. PMID: 41173941, DOI: 10.1038/s41467-025-64628-z.Peer-Reviewed Original ResearchIn Vivo Stability of Electronic Intraocular Lens Implant for Corneal Blindness
Vieira I, Fan V, Wiemer M, Lemoff B, Sood K, Mussa M, Yu C. In Vivo Stability of Electronic Intraocular Lens Implant for Corneal Blindness. Translational Vision Science & Technology 2025, 14: 33. PMID: 40569125, PMCID: PMC12205567, DOI: 10.1167/tvst.14.6.33.Peer-Reviewed Original ResearchConceptsCorneal blindnessIntraocular lensesTreatment of corneal blindnessAnterior chamber depthIntraocular lens implantationPosterior capsular opacificationIn vivo stabilityIris adhesionLens implantationCapsular opacificationEvidence of safetyChamber depthIntraocular implantsCrystalline lensesCornealLiving eyeCornea centerMonthsImplantationAxial stabilityBlindnessEyesTreatmentRabbitsCorneaDesign, Production and Study of Flexible Acrylic Keratoprosthesis
Fan V, Sun M, Al-Qahtani A, Vieira I, Yu C. Design, Production and Study of Flexible Acrylic Keratoprosthesis. Current Eye Research 2025, 50: 677-683. PMID: 40177932, PMCID: PMC12187538, DOI: 10.1080/02713683.2025.2485186.Peer-Reviewed Original ResearchConceptsTreatment of corneal blindnessCorneal blindnessMTT assayKeratoprosthesesHistological analysisComplex shapesImplantationSurgical implantationInjection molding techniquePilot studyBlindnessTreatmentFree radical polymerizationToxicityMaterial formulationMechanical propertiesMechanical characteristicsMolding techniqueAssayKeratoprosthesisCopolymer sheetsRadical polymerizationAcrylic sheetRefractive indexMonths
2022
Focal electrical stimulation of human retinal ganglion cells for vision restoration
Madugula S, Gogliettino A, Zaidi M, Aggarwal G, Kling A, Shah N, Brown J, Vilkhu R, Hays M, Nguyen H, Fan V, Wu E, Hottowy P, Sher A, Litke A, Silva R, Chichilnisky E. Focal electrical stimulation of human retinal ganglion cells for vision restoration. Journal Of Neural Engineering 2022, 19: 066040. PMID: 36533865, PMCID: PMC10010036, DOI: 10.1088/1741-2552/aca5b5.Peer-Reviewed Original ResearchConceptsHuman retinal ganglion cellsRetinal ganglion cellsElectrical stimulationVision restorationGanglion cellsExtracellular electrical stimulationPrimate retinal ganglion cellsFocal electrical stimulationRetina ex vivoRGC typesAxon bundlesEx vivoHuman retinaStimulationStimulation algorithmMulti-electrode arraysSimultaneous recordingEpiretinal implantsRetinaSimultaneous activationRetinal implantsCell typesNeural codeActivation propertiesMacaquesChronic bilateral multifocal superficial keratitis in a pediatric patient
Vieira IV, Fan VH, Duan C, Yu CQ. Chronic bilateral multifocal superficial keratitis in a pediatric patient. American Journal Of Ophthalmology Case Reports 2022, 26: 101495. PMID: 35355857, PMCID: PMC8958260, DOI: 10.1016/j.ajoc.2022.101495.Peer-Reviewed Original Research
2021
Automatic Identification of Axon Bundle Activation for Epiretinal Prosthesis
Tandon P, Bhaskhar N, Shah N, Madugula S, Grosberg L, Fan VH, Hottowy P, Sher A, Litke AM, Chichilnisky EJ, Mitra S. Automatic Identification of Axon Bundle Activation for Epiretinal Prosthesis. IEEE Transactions On Neural Systems And Rehabilitation Engineering 2021, 29: 2496-2502. PMID: 34784278, PMCID: PMC8860174, DOI: 10.1109/tnsre.2021.3128486.Peer-Reviewed Original ResearchConceptsAxon bundle activationRetinal ganglion cellsBundle activationAxonal stimulationEpiretinal prosthesisEx vivo stimulationStimulation current amplitudeGanglion cellsReceptive field locationMacaque retinaVivo stimulationElectrical stimulationAxon bundlesAxonal spikesStimulationProsthesisCortical implantsRetinal prosthesisActivationRetinal implantsVisual perceptsElectrical recordingsCellsInadvertent activationImplants
2020
Characterization of an Electronic Corneal Prosthesis System
Shim SY, Gong S, Fan VH, Rosenblatt MI, Al-Qahtani AF, Sun MG, Zhou Q, Kanu L, Vieira IV, Yu CQ. Characterization of an Electronic Corneal Prosthesis System. Current Eye Research 2020, 45: 914-920. PMID: 31886728, PMCID: PMC9997130, DOI: 10.1080/02713683.2019.1708957.Peer-Reviewed Original Research
2019
Epiretinal stimulation with local returns enhances selectivity at cellular resolution.
Fan VH, Grosberg LE, Madugula SS, Hottowy P, Dabrowski W, Sher A, Litke AM, Chichilnisky EJ. Epiretinal stimulation with local returns enhances selectivity at cellular resolution. Journal Of Neural Engineering 2019, 16: 025001. PMID: 30523958, PMCID: PMC6416068, DOI: 10.1088/1741-2552/aaeef1.Peer-Reviewed Original Research
2017
Activation of ganglion cells and axon bundles using epiretinal electrical stimulation
Grosberg LE, Ganesan K, Goetz GA, Madugula SS, Bhaskhar N, Fan V, Li P, Hottowy P, Dabrowski W, Sher A, Litke AM, Mitra S, Chichilnisky EJ. Activation of ganglion cells and axon bundles using epiretinal electrical stimulation. Journal Of Neurophysiology 2017, 118: 1457-1471. PMID: 28566464, PMCID: PMC5596129, DOI: 10.1152/jn.00750.2016.Peer-Reviewed Original ResearchConceptsRetinal ganglion cellsGanglion cellsIndividual ganglion cellsAxon bundlesBundle activationCentral retinaElectrical stimulationLarge-scale multielectrode recordingsEpiretinal prosthesisIndividual retinal ganglion cellsAxon bundle activationCombined electrical stimulationEpiretinal electrical stimulationFunction of stimulationPeripheral retinaPrimate retinaBundle activityMultielectrode recordingsRetinaEpiretinal stimulationElicit spikesStimulationBundle signalsSingle-spike resolutionProsthesis