Henna Nam
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Research
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2025
Multiplex gene editing models of del(7q) reveal combined CUX1 and EZH2 loss drives clonal expansion and drug resistance
Jotte M, Stoddart A, Martinez T, Moten R, Xue Y, Imgruet M, Blaylock H, Nam H, Hu B, Austin J, An N, Khan S, Gurbuxani S, McNerney M. Multiplex gene editing models of del(7q) reveal combined CUX1 and EZH2 loss drives clonal expansion and drug resistance. Blood Neoplasia 2025, 2: 100083. PMID: 40453147, PMCID: PMC12067884, DOI: 10.1016/j.bneo.2025.100083.Peer-Reviewed Original Research
2024
EZH2 inhibition enhances T cell immunotherapies by inducing lymphoma immunogenicity and improving T cell function
Isshiki Y, Chen X, Teater M, Karagiannidis I, Nam H, Cai W, Meydan C, Xia M, Shen H, Gutierrez J, Kumar V, Carrasco S, Ouseph M, Yamshon S, Martin P, Griess O, Shema E, Porazzi P, Ruella M, Brentjens R, Inghirami G, Zappasodi R, Chadburn A, Melnick A, Béguelin W. EZH2 inhibition enhances T cell immunotherapies by inducing lymphoma immunogenicity and improving T cell function. Cancer Cell 2024, 43: 49-68.e9. PMID: 39642889, PMCID: PMC11732734, DOI: 10.1016/j.ccell.2024.11.006.Peer-Reviewed Original Research
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