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Global Cat/Cyp2e1 DKO (Cat−/−/Cyp2e1−/−) strain

We generated the Cat/Cyp2e1 DKO mouse line by crossing the two single KO mouse lines. These mice are viable and fertile (manuscript in preparation). They will be a useful model for investigation of ethanol metabolism in the central nervous system, ethanol preference and ethanol toxicity in organs.