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People

Leadership

  • Flora Vaccarino

    Principal Investigator

    Harris Professor in the Child Study Center; Professor in the Department of Neuroscience

    Dr. Flora Vaccarino graduated in Medicine at Padua University in Italy and studied neuropharmacology and cell biology at NIH as a research fellow before starting her Residency in Psychiatry at Yale University. After her residency, she studied developmental biology and genetics and was appointed Assistant Professor at Yale University. Her interests are the development of the mammalian the cerebral cortex, basal ganglia and connected forebrain regions as well as the regulation of neural stem cells in both embryonic and postnatal periods. Her lab has been investigating how genetic (i.e., tyrosine growth factor receptors like Fibroblast Growth Factors) and epigenetic factors (i.e., perinatal hypoxia, environmental enrichment) affect the proliferation the maturation of neural progenitor cells in mouse models. Recently she has been exploring how induced pluripotent stem cells (iPSCs) can be used to model developmental neuropsychiatric disorders including autism and Rett syndrome. With a group of colleagues, Dr. Vaccarino, now a full Professor at Yale University School of Medicine, founded in 2009 the “Program in Neurodevelopment and Regeneration” (https://medicine.yale.edu/neurodevelopment/index.aspx), a collaborative interdepartmental program at Yale University that is leading interdisciplinary studies on iPSCs, neural stem cells and human development.Dr. Vaccarino is a Fellow of American Association for the Advancement of Science and a member of the PsychENCODE and the Brain Somatic Mosaicism Consortia.

Members

  • Alexandre Jourdon

    Postdoctoral Associate

    Postdoctoral Associate in the laboratory of Flora Vaccarino at Yale, Alex studies brain development, Somatic Mosaicism, and Autism Spectrum Disorder in vitro using induced Pluripotent Stem Cells (iPSC). He obtained his PhD in Paris, working in the laboratory of Patrick Charnay in the Biological Institute of the Ecole Normale Supérieure (ENS), and has a MS in Neuroscience (Paris University UPMC) and a Bioingeneering Degree from INSA (Lyon, France). Alex interests revolve around developmental neuroscience and stem cells biology. He worked on adult neurogenesis in mice and cortical development in iPSCs and is familiar with genomic projects. He is also an active member of the Yale Postdoctoral Association and dance salsa on his free time.

  • Eunice Yuen

    Clinical Fellow in the Child Study Center

    Eunice integrates her clinical training and research work in a Bio-Psycho-Social-Cultural framework. Her research in children mental health covers from basic science on genetics and neurobiology to community-based advocacy, education and intervention. Prior to residency training, Eunice’s research focuses on cellular and molecular mechanisms of emotional stress in synaptic transmission and plasticity (https://www.ncbi.nlm.nih.gov/myncbi/browse/collection/49501231/?sort=date&direction=ascending). Acculturative stress, a form of psychosocial stressor that experienced by most immigrants, negatively impacts children and families in our society. Eunice is the founder and director of Yale Compassionate Home, Action Together (CHATogether), a culturally- and family-oriented program using drama vignettes as educational tools to promote emotional wellness in Asian-American children, young adults, and parents.