Latest News from Vaccarino Lab
Scientists studying non-inherited, or somatic, mutations in frozen post-mortem human brains have found that about 6% of brains are much more likely to accumulate large numbers of these mutations and that these “hypermutable” brains tend to be 40 years old or older.
- July 26, 2022Source: For all issues, please visit: https://us14.campaign-archive.com/home/?u=075d4cacc1c5196316109f2cd&id=0f44120434
Human Excitation and Inhibition
- June 28, 2022
From mouse models, to pluripotent stem cell lines, to pioneering the construction and use of organoids, Flora Vaccarino has been at the forefront of brain research since joining the Yale School of Medicine faculty more than 25 years ago.
- May 24, 2021Source: The Allen Institute Conference on Human Brain Evolution
"Ancestry.com for the Human Body: Tracing Early Lineages Using Somatic Mutations in People"
- April 30, 2021
Awarded Yale Child Study Center “Clinical & Research Faculty Development Fund”
- April 27, 2021Source: Psychiatry Online
Using human-derived stem cells, researchers are now able to create stable and functional 3D constructs that mimic some aspects of brain development.
- April 13, 2021Source: Hosted by NeuroDev Disorders
"Lineage tracing through somatic mutations in living human individuals"
- March 19, 2021Source: Science Vol 371, Issue 6535
Fasching L, Jang Y, Tomasi S, Schreiner J, Tomasini L, Brady MV, Bae T, Sarangi V, Vasmatzis N, Wang Y, Szekely A, Fernandez TV, Leckman JF, Abyzov A, Vaccarino FM. Early developmental asymmetries in cell lineage trees in living individuals. Science. 2021 Mar 19. PMID: 33737484.
- March 18, 2021Source: YaleNews
Using skin cells harvested from two living humans, researchers in the lab of Yale’s Flora Vaccarino were able to track their cellular lineage by identifying tiny variations or mutations contained within the genomes of those cells.
- February 19, 2021
Soraya Scuderi, PhD wins a Pilot Research Award for Yale Child Study Center Trainees.