What is ACE?

Yale’s Autism Center of Excellence (ACE) Program aims to advance understanding of early neurodevelopment of children affected by autism.

The Yale ACE aims to:

  • identify neural signatures of ASD and evaluate their relevance to prediction of outcomes and response to intervention during prenatal, neonatal, and school-age period
  • identify sex-linked risk and protective factors in ASD
  • conduct an efficacy trial of a novel intervention targeting an early attentional marker of autism
  • examine cellular, molecular, and brain mechanisms in pairs of siblings concordant and discordant for ASD to isolate risk and protective factors for ASD

Results from the combined projects have the potential to identify novel diagnostic and prognostic markers, identify risk and protective mechanisms, and clarify neural bases of sex differences in ASD.


Our annual Autism Summer Institute will be held on July 11, 2019.

Our 4th annual Autism Conference was held on April 4, 2019.

ACE in the News

ACE was recently featured on News 8 WTNH. 

Click here to learn about Dr. Vaccarino's study of older children with autism and their siblings.