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Micrograph of human bronchial epithelial cells, seven hours after exposure to rhinovirus 1B. Rhinovirus infection of airway epithelial cells results in accumulation of double stranded RNA (dsRNA; blue) during viral genome replication. Cells are also stained with Mitotracker red to reveal the location of mitochondria, the cellular structures associated with innate immune signaling via the RIG-I like receptor pathway(red). Photograph courtesy of Ulysses Isidro, Yale University senior thesis student.