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Echocardiographic Core Laboratory

The Echocardiographic Core Laboratory (ECL) provides state-of-the-art echocardiographic imaging interpretation and analysis.

ECL director Lissa Sugeng, MD, MPH, is a Yale faculty board-certified cardiologist and a leading national expert in 2- and 3-dimensional echocardiographic measures, having validated many of the newer measures of LV volume and function using 3-dimensional echocardiography.


The ECG Core laboratory provides analytic measures critical to the evaluation of acute myocardial infarction in the context of clinical trials. Core laboratory analysis of ECG data provides:

  • Standardized assessment of Q wave and ST-segment resolution
  • Consistent adjudication of interval or pre-existing MI
  • Baseline data for event adjudication during long-term follow up
  • Facilitated assessment of TV/TL relationship in the adjudication of MI and key composite endpoint events


The ECG Core Laboratory includes trained readers and physician over-readers, and uses standard methods to evaluate ischemic endpoints. The ECG Core Laboratory has passed numerous vendor-initiated audits.