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Dr. Henry Yaggi featured on AJRCCM Podcast: Symptom Subtypes of OSA Predict Incidence of Cardiovascular Outcome
Dr. John Fleetham is joined by Drs. Diego Mazzotti and Henry Yaggi to discuss the paper "Symptom Subtypes of Obstructive Sleep Apnea Predict Incidence of Cardiovascular Outcomes". Dr. Yaggi explains the importance of phenotyping patients with obstructive sleep apnea regarding different disease symptom that allows for a more personal treatment, better understanding of mechanism, prognosis, and designed clinical trials. The podcast also speaks of two additional models of phenotyping: implementing the supervised learning approach and unsupervised learning approach. Finally, he gives his expertise on the strength of the study, the foundational role it can serve for future studies involving sleep apnea as many previous major studies focused exclusively on non-sleepy patients, strategies to safely/ethically recruit future sleepy patients for clinical studies, and future directions of linking phenotyping to clinically relevant outcomes for personalized treatment.
Source: Apple Podcasts