Skip to Main Content
Diseases of the Digestive System - Liver | Genetics - Adult

Genetic Studies of Polycystic Livers

What is the purpose of this trial?

Our study will use genetic testing of people with multiple liver cysts to help explain the cause of liver and kidney cysts. The combination of liver and kidney cysts occurs most often in autosomal dominant polycystic kidney (ADPKD). People with ADPKD often have mostly kidney cysts and these cysts cause kidney failure in many individuals. The genetic causes of ADPKD are known, but treatments are still desperately needed.

Our study is focused on people who have liver cysts alone or with few kidney cysts, because the genetic causes of this are largely unknown but are relevant to both conditions. Most people with liver cysts will never know they have liver cysts and their cysts will not make them sick. Only rarely does this condition progress to causing symptoms requiring treatment. We would like to enroll anyone with many liver cysts meeting our criteria. We then use genetic testing and analysis to discovery gene mutations that cause liver cysts. Our goal is to find and study these genes in order to find targets for treatment of liver and kidney cysts in the future.

Participation requires a one-time blood or saliva sample for research genetic testing. Participants must be 18 years of age. Information is kept strictly confidential, although genetic results can be communicated via your physician upon request.

If you are interested, please complete this HIPAA compliant survey. A study team member will reach out to you.

  • Trial with
    Robert Leet and Clara Guthrie Patterson Trust, Polycystic Kidney Disease (PKD) Foundation, and National Institute of Diabetes and Digestive & Kidney Diseases (NIDDK)
  • Ages
    18 years and older
  • Gender

Contact Information

For more information about this study, including how to volunteer, contact Whitney Besse

Help Us Discover!

You can help our team find trials you might be eligible for by creating a volunteer profile in MyChart. To get started, create a volunteer profile, or contact, or call 877.978.8343 for more information.

  • Last Updated
  • Study HIC