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Research Areas

The research activities of our faculty cover a broad range of topics in renal physiology and nephrology from laboratory bench to patient oriented investigation. Current areas of research focus include studies of the mechanisms of acute kidney injury and repair, molecular genetics of polycystic kidney disease and other cilia related disorders, renal tubular electrolyte transport and acid base regulation, renal epithelial cell biology and morphogenesis, and biomarkers in acute kidney injury and other kidney diseases.

In addition to a large spectrum of research projects supported by individual NIH research grants, the Yale Section of Nephrology is home to two NIH-funded centers of kidney disease research excellence, the George M. O’Brien Kidney Center at Yale and the Yale Center for the Study of Polycystic Kidney Disease.

The Clinical and Translational Research Accelerator recruits scientists and trains students in methods of translational research and offers access to a large biorepository of samples and national databases for research projects.