Robert Safirstein, MD
Professor of Medicine (Nephrology)
Research & Publications
Biography
News
Coauthors
Selected Publications
- COMBINED EFFECTS OF CHILD AND ADULT ELEVATED BLOOD PRESSURE ON ADULT SUBCLINICAL KIDNEY DAMAGE AND ALBUMINURIA: A 36-YEAR PROSPECTIVE COHORT STUDYWang Y, Jia H, Du M, Sun Y, Wang D, Hu G, Man Z, Chu C, Desir G, Safirstein R, Zheng X, Mu J. COMBINED EFFECTS OF CHILD AND ADULT ELEVATED BLOOD PRESSURE ON ADULT SUBCLINICAL KIDNEY DAMAGE AND ALBUMINURIA: A 36-YEAR PROSPECTIVE COHORT STUDY. Journal Of Hypertension 2024, 42: e204. DOI: 10.1097/01.hjh.0001021508.55729.ea.
- APOBEC-1 deletion enhances cisplatin-induced acute kidney injuryGuo X, Blanc V, Davidson N, Velazquez H, Chen T, Moledina D, Moeckel G, Safirstein R, Desir G. APOBEC-1 deletion enhances cisplatin-induced acute kidney injury. Scientific Reports 2023, 13: 22255. PMID: 38097707, PMCID: PMC10721635, DOI: 10.1038/s41598-023-49575-3.
- mRNA Editing via the Apobec1 Gene Promotes Recovery from AKIGuo X, Velazquez H, Xu L, Cheng Z, Chen T, Tian Y, Bewersdorf J, Blanc V, Davidson N, Safirstein R, Desir G. mRNA Editing via the Apobec1 Gene Promotes Recovery from AKI. Journal Of The American Society Of Nephrology 2023, 34: 451-451. DOI: 10.1681/asn.20233411s1451b.
- Renalase Ameliorates AKI by Altering Mitochondrial Function to Induce Cellular Repair MechanismsGuo X, Chen R, Chen T, Safirstein R, Jonas E, Desir G. Renalase Ameliorates AKI by Altering Mitochondrial Function to Induce Cellular Repair Mechanisms. Journal Of The American Society Of Nephrology 2023, 34: 117-117. DOI: 10.1681/asn.20233411s1117b.
- Abstract 13764: Renalase Peptide Agonist Therapy Normalizes the Cardiac Response to Pressure Overload in Chronic Kidney DiseaseNair G, Zhang J, Guo X, guerrera N, Wu X, Hu X, Gorelick F, Safirstein R, Giordano F, Young L, Desir G. Abstract 13764: Renalase Peptide Agonist Therapy Normalizes the Cardiac Response to Pressure Overload in Chronic Kidney Disease. Circulation 2022, 146: a13764-a13764. DOI: 10.1161/circ.146.suppl_1.13764.
- Apobec-1 Limits Cisplatin and Ischemia-Reperfusion-Induced AKIGuo X, Xu L, Velazquez H, Chen T, Blanc V, Davidson N, Moeckel G, Safirstein R, Desir G. Apobec-1 Limits Cisplatin and Ischemia-Reperfusion-Induced AKI. Journal Of The American Society Of Nephrology 2022, 33: 359-360. DOI: 10.1681/asn.20223311s1359e.
- Renalase Protects Renal Injury by Maintaining Mitochondrial Dynamic HomeostasisGuo X, Chen R, Chen T, Moeckel G, Safirstein R, Jonas E, Desir G. Renalase Protects Renal Injury by Maintaining Mitochondrial Dynamic Homeostasis. Journal Of The American Society Of Nephrology 2022, 33: 359-359. DOI: 10.1681/asn.20223311s1359d.
- Early life body mass index trajectories and albuminuria in midlife: A 30-year prospective cohort studyWang Y, Li F, Chu C, Zhang X, Zhang X, Liao Y, Du M, Zou T, Ma Q, Chen C, Wang D, Wang K, Yan Y, Sun Y, Hu G, Jia H, Li H, Niu Z, Yan R, Man Z, Wang L, Luo W, Zhang J, Li C, Lu W, Chang J, Safirstein R, Lu Y, Mu J. Early life body mass index trajectories and albuminuria in midlife: A 30-year prospective cohort study. EClinicalMedicine 2022, 48: 101420. PMID: 35516445, PMCID: PMC9065297, DOI: 10.1016/j.eclinm.2022.101420.
- Heightened Innate Immune Response to COVID-19 Infection in CKD: Implications to Poorer Outcome During CKDGuo X, Xu L, Chen T, Gorelick F, Desir G, Safirstein R. Heightened Innate Immune Response to COVID-19 Infection in CKD: Implications to Poorer Outcome During CKD. Journal Of The American Society Of Nephrology 2021, 32: 749-749. DOI: 10.1681/asn.20213210s1749c.
- Kidney Targeted Renalase Agonist Peptide Rescues Severe Model of Cisplatin-Induced AKI and CKDGuo X, Xu L, Velazquez H, Chen T, Williams R, Heller D, Safirstein R, Desir G. Kidney Targeted Renalase Agonist Peptide Rescues Severe Model of Cisplatin-Induced AKI and CKD. Journal Of The American Society Of Nephrology 2020, 31: 230-230. DOI: 10.1681/asn.20203110s1230b.
- Apobec 1 Limits Cisplatin-Induced AKI by Regulating the Disposal of Pro-Ferroptotic LipidsGuo X, Velazquez H, Chen T, Blanc V, Davidson N, Safirstein R, Desir G. Apobec 1 Limits Cisplatin-Induced AKI by Regulating the Disposal of Pro-Ferroptotic Lipids. Journal Of The American Society Of Nephrology 2020, 31: 123-123. DOI: 10.1681/asn.20203110s1123d.
- Renalase protects against cisplatin acute kidney injury in miceDesir G, Wang L, Velazquez H, Moeckel G, Safirstein R. Renalase protects against cisplatin acute kidney injury in mice. The FASEB Journal 2013, 27: 910.7-910.7. DOI: 10.1096/fasebj.27.1_supplement.910.7.