2021
Presentation, Treatment, and Outcomes of Older Adults Hospitalized for Acute Myocardial Infarction According to Cognitive Status: The SILVER-AMI Study
Hajduk AM, Saczynski JS, Tsang S, Geda ME, Dodson JA, Ouellet GM, Goldberg RJ, Chaudhry SI. Presentation, Treatment, and Outcomes of Older Adults Hospitalized for Acute Myocardial Infarction According to Cognitive Status: The SILVER-AMI Study. The American Journal Of Medicine 2021, 134: 910-917. PMID: 33737057, PMCID: PMC8243828, DOI: 10.1016/j.amjmed.2021.03.003.Peer-Reviewed Original ResearchConceptsSevere cognitive impairmentAcute myocardial infarctionMyocardial infarctionCognitive impairmentOlder acute myocardial infarction patientsCognitive statusMultivariable-adjusted logistic regressionAcute myocardial infarction patientsOlder adultsRoutine cognitive screeningRisk of readmissionMedical record reviewRisk of deathPost-discharge periodMyocardial infarction patientsMyocardial infarction survivorsSILVER-AMI StudyComorbidity burdenHospital readmissionPoor outcomeRecord reviewFunctional statusInfarction patientsUnadjusted analysesInfarction survivors
2019
Patient-Reported Quality of Hospital Discharge Transitions: Results from the SILVER-AMI Study
Richards BG, Hajduk AM, Perry J, Krumholz HM, Khan AM, Chaudhry SI. Patient-Reported Quality of Hospital Discharge Transitions: Results from the SILVER-AMI Study. Journal Of General Internal Medicine 2019, 35: 808-814. PMID: 31654359, PMCID: PMC7080904, DOI: 10.1007/s11606-019-05414-8.Peer-Reviewed Original ResearchConceptsDays of dischargeEmergency department utilizationAcute myocardial infarctionPatient-reported qualityHospital discharge processOlder patientsAcute Myocardial Infarction StudyMyocardial Infarction StudyProspective cohort studyMedical record reviewEmergency room utilizationAdults age 75Key ResultsA totalHospital Consumer AssessmentSILVER-AMI StudyHospital discharge transitionsHigh-risk periodDesignMulti-centerCohort studyHospital dischargeMedian ageClinical outcomesRecord reviewAdverse outcomesResultsA total
2016
Restricting Symptoms Before and After Admission to Hospice
Cheraghlou S, Gahbauer EA, Leo-Summers L, Stabenau HF, Chaudhry SI, Gill TM. Restricting Symptoms Before and After Admission to Hospice. The American Journal Of Medicine 2016, 129: 754.e7-754.e15. PMID: 26968471, PMCID: PMC4914433, DOI: 10.1016/j.amjmed.2016.02.017.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAgedAged, 80 and overChest PainCognitive DysfunctionCohort StudiesDepressionDiarrheaDizzinessDyspneaEdemaFatigueFemaleHospice CareHospicesHumansIndependent LivingLongitudinal StudiesMaleMemory DisordersMuscle WeaknessMusculoskeletal PainNauseaPatient AdmissionPrevalenceProspective StudiesSleep Wake DisordersUnited StatesUrologic DiseasesVision DisordersVomitingConceptsHospice admissionEnd of lifeDistressing symptomsMean numberCommunity-dwelling older personsMonthly telephone interviewsOngoing cohort studyMonths of lifeEffect of hospiceHospice treatmentAdmission diagnosisEarly referralMedian durationCohort studySymptom prevalenceSuch symptomsSymptom increasesAdmissionPsychological symptomsSymptomsOlder personsRestricted activityHospiceTelephone interviewsPrevalenceSlow Gait Speed and Risk of Mortality or Hospital Readmission After Myocardial Infarction in the Translational Research Investigating Underlying Disparities in Recovery from Acute Myocardial Infarction: Patients' Health Status Registry
Dodson JA, Arnold SV, Gosch KL, Gill TM, Spertus JA, Krumholz HM, Rich MW, Chaudhry SI, Forman DE, Masoudi FA, Alexander KP. Slow Gait Speed and Risk of Mortality or Hospital Readmission After Myocardial Infarction in the Translational Research Investigating Underlying Disparities in Recovery from Acute Myocardial Infarction: Patients' Health Status Registry. Journal Of The American Geriatrics Society 2016, 64: 596-601. PMID: 26926309, PMCID: PMC4803531, DOI: 10.1111/jgs.14016.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionMyocardial infarctionSlow gaitHospital readmissionGait speedOlder adultsCox proportional hazards regressionMarker of frailtySlow gait speedTranslational researchProportional hazards regressionOutcomes 1 yearRisk of mortalityAssessment 1 monthBaseline characteristicsObservational cohortClinical factorsDiabetes mellitusHeart failureHazards regressionPrognostic importancePrognostic valueHigh prevalenceInfarctionReadmission
2015
Burden of Comorbidities and Functional and Cognitive Impairments in Elderly Patients at the Initial Diagnosis of Heart Failure and Their Impact on Total Mortality The Cardiovascular Health Study
Murad K, Goff DC, Morgan TM, Burke GL, Bartz TM, Kizer JR, Chaudhry SI, Gottdiener JS, Kitzman DW. Burden of Comorbidities and Functional and Cognitive Impairments in Elderly Patients at the Initial Diagnosis of Heart Failure and Their Impact on Total Mortality The Cardiovascular Health Study. JACC Heart Failure 2015, 3: 542-550. PMID: 26160370, PMCID: PMC4499113, DOI: 10.1016/j.jchf.2015.03.004.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAgedAged, 80 and overAtrial FibrillationCognition DisordersCohort StudiesComorbidityCoronary DiseaseFemaleHeart FailureHumansHypertensionIncidenceLongitudinal StudiesMalePeripheral Arterial DiseasePhysical FitnessPrevalenceProportional Hazards ModelsPulmonary Disease, Chronic ObstructiveConceptsIncident heart failureCardiovascular Health StudyHeart failureGreater mortality riskMortality riskPercent of participantsCognitive impairmentElderly patientsFunctional impairmentDaily livingHealth StudyBurden of comorbiditiesChronic kidney diseaseMultivariable-adjusted modelsTotal mortality riskRelevant comorbiditiesDiabetes mellitusInitial diagnosisCerebrovascular diseaseKidney diseaseMean ageHigh burdenComorbiditiesInstrumental activitiesMortality rate
2013
Risk Factors for Hospital Admission Among Older Persons With Newly Diagnosed Heart Failure Findings From the Cardiovascular Health Study
Chaudhry SI, McAvay G, Chen S, Whitson H, Newman AB, Krumholz HM, Gill TM. Risk Factors for Hospital Admission Among Older Persons With Newly Diagnosed Heart Failure Findings From the Cardiovascular Health Study. Journal Of The American College Of Cardiology 2013, 61: 635-642. PMID: 23391194, PMCID: PMC3576871, DOI: 10.1016/j.jacc.2012.11.027.Peer-Reviewed Original ResearchConceptsHeart failure diagnosisIndependent risk factorHospital admissionCardiovascular Health StudyHeart failureGeriatric conditionsRisk factorsMuscle weaknessSlow gaitOlder personsHealth StudyNew diagnosisNew York Heart Association functional class IIICommunity-living older personsDepressed ejection fractionHeart Failure FindingsFunctional class IIIChronic kidney diseaseCause hospital admissionsMedical record reviewRelevant clinical dataLong-term riskDiabetes mellitusEjection fractionKidney diseaseResults Differ by Applying Distinctive Multiple Imputation Approaches on the Longitudinal Cardiovascular Health Study Data
Ning Y, McAvay G, Chaudhry SI, Arnold AM, Allore HG. Results Differ by Applying Distinctive Multiple Imputation Approaches on the Longitudinal Cardiovascular Health Study Data. Experimental Aging Research 2013, 39: 27-43. PMID: 23316735, PMCID: PMC3547387, DOI: 10.1080/0361073x.2013.741968.Peer-Reviewed Original Research
2011
Impact of Comorbidity on Mortality Among Older Persons with Advanced Heart Failure
Ahluwalia SC, Gross CP, Chaudhry SI, Ning YM, Leo-Summers L, Van Ness PH, Fried TR. Impact of Comorbidity on Mortality Among Older Persons with Advanced Heart Failure. Journal Of General Internal Medicine 2011, 27: 513-519. PMID: 22095572, PMCID: PMC3326095, DOI: 10.1007/s11606-011-1930-3.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overChronic DiseaseCohort StudiesComorbidityFemaleHeart DiseasesHeart FailureHip FracturesHospitalizationHumansKaplan-Meier EstimateKidney DiseasesLongitudinal StudiesMaleMedicarePrevalencePrognosisPulmonary Disease, Chronic ObstructiveRetrospective StudiesRisk FactorsUnited StatesConceptsChronic obstructive pulmonary diseaseImpact of comorbiditiesAdvanced heart failureHeart failureHigher mortality riskMortality riskComorbidity burdenHip fractureMyocardial infarctionOlder adultsCount of conditionsOverall comorbidity burdenRetrospective cohort studyContribution of comorbiditiesObstructive pulmonary diseaseProportional hazards regressionLower mortality riskLife-prolonging interventionsHF mortalityHospitalized beneficiariesMost comorbiditiesCohort studyIndividual comorbiditiesPrior hospitalizationPulmonary diseaseRisk Factors for Onset of Disability Among Older Persons Newly Diagnosed With Heart Failure: The Cardiovascular Health Study
Chaudhry SI, McAvay G, Ning Y, Allore HG, Newman AB, Gill TM. Risk Factors for Onset of Disability Among Older Persons Newly Diagnosed With Heart Failure: The Cardiovascular Health Study. Journal Of Cardiac Failure 2011, 17: 764-770. PMID: 21872147, PMCID: PMC3164529, DOI: 10.1016/j.cardfail.2011.04.015.Peer-Reviewed Original ResearchConceptsOnset of disabilityCardiovascular Health StudyHeart failureRisk factorsOlder personsHealth StudyHeart failure populationHeart failure diagnosisTime-dependent predictorsFailure populationGait speedStudy populationDepressive symptomsAnnual examinationsGreater riskDisabilityLongitudinal studyRegression modelingOnsetFirst yearFailureCommon occurrencePopulationPersonsParticipantsChange in Comorbidity Prevalence with Advancing Age Among Persons with Heart Failure
Ahluwalia SC, Gross CP, Chaudhry SI, Leo-Summers L, Van Ness PH, Fried TR. Change in Comorbidity Prevalence with Advancing Age Among Persons with Heart Failure. Journal Of General Internal Medicine 2011, 26: 1145-1151. PMID: 21573881, PMCID: PMC3181289, DOI: 10.1007/s11606-011-1725-6.Peer-Reviewed Original ResearchConceptsHeart failureDiscordant comorbiditiesComorbidity burdenMedicare beneficiariesDiscordant conditionsOlder personsChronic Conditions WarehouseCount of conditionsOverall comorbidity burdenHigher overall burdenOlder Medicare beneficiariesPatterns of comorbidityComorbidity prevalencePrimary illnessPrevalence increasesOverall burdenMedian numberComorbiditiesGreater prevalenceAge strataConcordant conditionsPrevalenceUnrelated conditionsOverall managementOlder beneficiaries