2015
Burden of Comorbidities and Functional and Cognitive Impairments in Elderly Patients at the Initial Diagnosis of Heart Failure and Their Impact on Total Mortality The Cardiovascular Health Study
Murad K, Goff DC, Morgan TM, Burke GL, Bartz TM, Kizer JR, Chaudhry SI, Gottdiener JS, Kitzman DW. Burden of Comorbidities and Functional and Cognitive Impairments in Elderly Patients at the Initial Diagnosis of Heart Failure and Their Impact on Total Mortality The Cardiovascular Health Study. JACC Heart Failure 2015, 3: 542-550. PMID: 26160370, PMCID: PMC4499113, DOI: 10.1016/j.jchf.2015.03.004.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAgedAged, 80 and overAtrial FibrillationCognition DisordersCohort StudiesComorbidityCoronary DiseaseFemaleHeart FailureHumansHypertensionIncidenceLongitudinal StudiesMalePeripheral Arterial DiseasePhysical FitnessPrevalenceProportional Hazards ModelsPulmonary Disease, Chronic ObstructiveConceptsIncident heart failureCardiovascular Health StudyHeart failureGreater mortality riskMortality riskPercent of participantsCognitive impairmentElderly patientsFunctional impairmentDaily livingHealth StudyBurden of comorbiditiesChronic kidney diseaseMultivariable-adjusted modelsTotal mortality riskRelevant comorbiditiesDiabetes mellitusInitial diagnosisCerebrovascular diseaseKidney diseaseMean ageHigh burdenComorbiditiesInstrumental activitiesMortality rate
2014
Place of Residence and Outcomes of Patients With Heart Failure
Bikdeli B, Wayda B, Bao H, Ross JS, Xu X, Chaudhry SI, Spertus JA, Bernheim SM, Lindenauer PK, Krumholz HM. Place of Residence and Outcomes of Patients With Heart Failure. Circulation Cardiovascular Quality And Outcomes 2014, 7: 749-756. PMID: 25074375, PMCID: PMC5323058, DOI: 10.1161/circoutcomes.113.000911.Peer-Reviewed Original ResearchConceptsNeighborhood socioeconomic statusIndividual socioeconomic statusOutcomes of patientsHeart failureHigher SES neighborhoodsSocioeconomic statusClinical factorsHeart Failure Outcomes trialPrimary end pointPatient-level factorsUS internal medicineCause mortalityCause readmissionMultivariable adjustmentOutcome trialsMedical chartsPatient interviewsLow-SES neighborhoodsCardiology practiceMortality ratePatientsPlace of residenceInternal medicineReadmissionEnd point
2010
Geriatric Conditions and Subsequent Mortality in Older Patients With Heart Failure
Chaudhry SI, Wang Y, Gill TM, Krumholz HM. Geriatric Conditions and Subsequent Mortality in Older Patients With Heart Failure. Journal Of The American College Of Cardiology 2010, 55: 309-316. PMID: 20117435, PMCID: PMC2832791, DOI: 10.1016/j.jacc.2009.07.066.Peer-Reviewed Original ResearchConceptsLong-term mortalityGeriatric conditionsNet reclassification improvementMobility disabilityOlder patientsReclassification improvementRisk factorsMultivariable logistic regression modelHeart failure hospitalizationIndependent risk factorTraditional risk factorsMedical record dataFinal multivariable modelYears of ageLogistic regression modelsFailure hospitalizationTerm mortalityHeart failureIndependent predictorsPrognostic importanceMean ageMultivariable modelMedicare beneficiariesMortality rateSubsequent mortality