Research Gaps on Methadone Harms and Comparative Harms: Findings From a Review of the Evidence for an American Pain Society and College on Problems of Drug Dependence Clinical Practice Guideline
Weimer MB, Chou R. Research Gaps on Methadone Harms and Comparative Harms: Findings From a Review of the Evidence for an American Pain Society and College on Problems of Drug Dependence Clinical Practice Guideline. Journal Of Pain 2014, 15: 366-376. PMID: 24685460, DOI: 10.1016/j.jpain.2014.01.496.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsAmerican Pain SocietyClinical practice guidelinesMethadone safetyPain SocietyAdverse eventsPractice guidelinesInsufficient evidenceEvidence-based clinical practice guidelinesSystematic reviewDependence Clinical Practice GuidelineMost guideline recommendationsTitration of therapyProlonged QTc intervalUrine drug testingLack of evidenceMethadone useGuideline recommendationsQTc intervalCochrane LibrarySafe prescribingRisk factorsUpdate searchOvid MEDLINEInclusion criteriaMethadone prescribingMethadone Overdose and Cardiac Arrhythmia Potential: Findings From a Review of the Evidence for an American Pain Society and College on Problems of Drug Dependence Clinical Practice Guideline
Chou R, Weimer MB, Dana T. Methadone Overdose and Cardiac Arrhythmia Potential: Findings From a Review of the Evidence for an American Pain Society and College on Problems of Drug Dependence Clinical Practice Guideline. Journal Of Pain 2014, 15: 338-365. PMID: 24685459, DOI: 10.1016/j.jpain.2014.01.495.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsAmerican Pain SocietyMethadone useChronic painPain SocietyClinical guidelinesArrhythmia potentialDependence Clinical Practice GuidelineMethadone-related deathsQTc interval prolongationUse of methadoneClinical practice guidelinesCardiac arrhythmia riskMarked increaseNumber of deathsMethadone safetyMortality benefitCardiac riskInterval prolongationOpioid dependenceQTc intervalAdverse outcomesCochrane LibraryMethadone overdoseCase reportPsychiatric admissions