A randomized trial of buprenorphine maintenance for heroin dependence in a primary care clinic for substance users versus a methadone clinic
O’Connor P, Oliveto A, Shi J, Triffleman E, Carroll K, Kosten T, Rounsaville B, Pakes J, Schottenfeld R. A randomized trial of buprenorphine maintenance for heroin dependence in a primary care clinic for substance users versus a methadone clinic. The American Journal Of Medicine 1998, 105: 100-105. PMID: 9727815, DOI: 10.1016/s0002-9343(98)00194-6.Peer-Reviewed Original ResearchConceptsPrimary care clinicsPrimary care settingBuprenorphine maintenanceCare clinicsDrug treatment programsHeroin dependenceOpioid useUrine toxicologyCare settingsTreatment programOpioid withdrawal symptomsOpioid-dependent patientsIllicit opioid useThrice weekly basisSecondary outcomesPrimary outcomeMaintenance treatmentWithdrawal symptomsMethadone clinicsPrimary careClinical trialsDrug treatmentEffective treatmentConsecutive weeksCocaine use