2010
Observational Methods in Comparative Effectiveness Research
Concato J, Lawler EV, Lew RA, Gaziano JM, Aslan M, Huang GD. Observational Methods in Comparative Effectiveness Research. The American Journal Of Medicine 2010, 123: e16-e23. PMID: 21184862, DOI: 10.1016/j.amjmed.2010.10.004.Peer-Reviewed Original ResearchConceptsComparative effectiveness researchObservational studyGroup of patientsVeterans Health AdministrationEffectiveness researchSpecific medical conditionsPatient-oriented researchCorresponding study designPatient populationTreatment optionsMedical conditionsHealth AdministrationStudy designMedical ailmentsIndividual studiesAvailable optionsPatientsRCTsOptionsProminent featureStudyAdministrationTrials
2005
Predicting which patients can resume oral nutrition after percutaneous endoscopic gastrostomy tube placement
Naik A, Abraham N, Roche V, Concato J. Predicting which patients can resume oral nutrition after percutaneous endoscopic gastrostomy tube placement. Alimentary Pharmacology & Therapeutics 2005, 21: 1155-1161. PMID: 15854179, DOI: 10.1111/j.1365-2036.2005.02464.x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCohort StudiesEndoscopy, GastrointestinalEnteral NutritionGastrostomyHumansMiddle AgedRetrospective StudiesTreatment OutcomeConceptsPercutaneous endoscopic gastrostomy placementEndoscopic gastrostomy placementOral nutritionGastrostomy placementTube removalNeck cancerLocalized headPercutaneous endoscopic gastrostomy (PEG) tube placementPercutaneous endoscopic gastrostomy removalBivariate analysisClinical goalsEndoscopic gastrostomy tube placementPercutaneous endoscopic gastrostomy tubeTemporary nutritional supportBaseline clinical characteristicsObservational cohort studyPotential clinical predictorsGastrostomy tube placementProportional hazards modelVariety of indicationsGastrostomy removalClinical characteristicsOlder patientsSerum creatinineClinical predictors
2000
Randomized, Controlled Trials, Observational Studies, and the Hierarchy of Research Designs
Concato J, Shah N, Horwitz R. Randomized, Controlled Trials, Observational Studies, and the Hierarchy of Research Designs. New England Journal Of Medicine 2000, 342: 1887-1892. PMID: 10861325, PMCID: PMC1557642, DOI: 10.1056/nejm200006223422507.Peer-Reviewed Original ResearchConceptsCase-control studyObservational studyBacille Calmette-Guérin (BCG) vaccineCalmette-Guérin vaccineRandomized clinical trialsClinical topicsIndividual observational studiesEffect of vaccinationEffect of treatmentMEDLINE data baseActive tuberculosisControlled TrialsPercent confidence intervalsClinical trialsOdds ratioRelative riskSummary estimatesMajor medical journalsSame interventionTrialsResearch designConfidence intervalsHigh gradeTreatment effectsOriginal report