An observational human study investigating the effect of anabolic androgenic steroid use on the transcriptome of skeletal muscle and whole blood using RNA-Seq
Kolliari-Turner A, Lima G, Wang G, Malinsky F, Karanikolou A, Eichhorn G, Tanisawa K, Ospina-Betancurt J, Hamilton B, Kumi P, Shurlock J, Skiadas V, Twycross-Lewis R, Kilduff L, Martin R, Ash G, Potter C, Guppy F, Seto J, Fossati C, Pigozzi F, Borrione P, Pitsiladis Y. An observational human study investigating the effect of anabolic androgenic steroid use on the transcriptome of skeletal muscle and whole blood using RNA-Seq. BMC Medical Genomics 2023, 16: 94. PMID: 37138349, PMCID: PMC10157927, DOI: 10.1186/s12920-023-01512-z.Peer-Reviewed Original ResearchMeSH KeywordsAnabolic AgentsAnabolic Androgenic SteroidsHumansMaleMuscle, SkeletalProteomicsRNA-SeqTestosterone CongenersTranscriptomeConceptsAnabolic androgenic steroidsWhole bloodWhole blood transcriptional signaturesBlood transcriptional signaturesSkeletal muscleTranscriptional signatureObservational human studiesLong-term cessationAnabolic-androgenic steroid useSteroid useAAS exposureSedentary controlsAndrogen receptorBackgroundThe effectsHuman studiesHypertrophic processAndrogenic steroidsHuman whole bloodAAS usersBloodGroup comparisonsTime pointsTraining regimensMuscleAAS usage