2015
Glycosylated hemoglobin is associated with decreased endothelial function, high inflammatory response, and adverse clinical outcome in non-diabetic STEMI patients
Moura F, Figueiredo V, Teles B, Barbosa M, Pereira L, Costa A, Carvalho L, Cintra R, Almeida O, Quinaglia e Silva J, Nadruz W, Sposito A, Study B. Glycosylated hemoglobin is associated with decreased endothelial function, high inflammatory response, and adverse clinical outcome in non-diabetic STEMI patients. Atherosclerosis 2015, 243: 124-130. PMID: 26385505, DOI: 10.1016/j.atherosclerosis.2015.09.004.Peer-Reviewed Original ResearchMeSH KeywordsAgedBlood GlucoseBrachial ArteryCoronary AngiographyC-Reactive ProteinDiabetes MellitusDietEndothelium, VascularFemaleFollow-Up StudiesGlycated HemoglobinHumansInflammationMagnetic Resonance ImagingMaleMiddle AgedMyocardial InfarctionNitric OxidePatient AdmissionPercutaneous Coronary InterventionProspective StudiesRisk FactorsROC CurveSensitivity and SpecificityTreatment OutcomeConceptsST-elevation myocardial infarctionFlow-mediated dilationNon-diabetic STEMI patientsC-reactive proteinSTEMI patientsEndothelial functionFollow-upInflammatory responseLong-term risk of MACEIncident diabetesLower HbA1cMedian follow-upClinical follow-upDecreased endothelial functionNon-diabetic patientsRisk of MACEAdverse cardiac eventsAdverse clinical outcomesIncreased inflammatory responseROC curve analysisSudden cardiac deathMeasured plasma glucoseNon-fatal MIPercutaneous coronary interventionLong-term risk
2014
Arterial tissue and plasma concentration of enzymatic-driven oxysterols are associated with severe peripheral atherosclerotic disease and systemic inflammatory activity
Virginio V, Nunes V, Moura F, Menezes F, Andreollo N, Rogerio F, Scherrer D, Quintão E, Nakandakare E, Petrucci O, Nadruz-Junior W, de Faria E, Sposito A. Arterial tissue and plasma concentration of enzymatic-driven oxysterols are associated with severe peripheral atherosclerotic disease and systemic inflammatory activity. Free Radical Research 2014, 49: 199-203. PMID: 25465091, DOI: 10.3109/10715762.2014.992894.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overArteriesC-Reactive ProteinFemaleHumansHydroxycholesterolsInflammationMaleMiddle AgedPeripheral Arterial DiseaseConceptsPeripheral arterial diseaseSevere peripheral arterial diseaseAtherosclerotic diseasePlasma C-reactive proteinFree of atherosclerotic plaquesSystemic inflammatory activityC-reactive proteinPeripheral atherosclerotic diseaseFree radical-mediated mechanismAtherosclerotic plaquesAdvanced atherosclerotic diseaseArterial tissueArtery diseaseInflammatory activityPlasma concentrationsEnzymatic stressDiseaseArteryRadical-mediated mechanismPlasmaPlaqueOxysterolsTissue