Mathieu Bakhoum, MD, PhD
Cards
About
Titles
Assistant Professor of Ophthalmology and Visual Science
Biography
Mathieu Bakhoum is a physician scientist with clinical training in ophthalmology and vitreoretinal surgery. At the Yale Eye Center, he cares for patients with complex retinal diseases such as age-related macular degeneration, diabetic retinopathy, retinal detachment, epiretinal membrane and retinal artery and vein occlusions.
His laboratory at the Yale School of Medicine focuses on two research areas with direct clinical applications. The first is to determine mechanisms that drive metastasis in uveal melanoma, a lethal eye cancer. His goal is to translate this knowledge to develop non-invasive biomarkers for diagnosis and metastatic surveillance, and to identify druggable targets that can be employed to treat the primary and metastatic disease. His work has identified a novel mechanism by which cancer cells evolve to become more aggressive. The second area of focus capitalizes upon the ability to visualize the individual cellular layers of the retina during routine eye examination, and utilizes this information to detect underlying systemic diseases. Dr. Bakhoum has demonstrated that retinal ischemic perivascular lesions (RIPLs) can be used as a biomarker for underlying cardiovascular disease. Early detection of cardiovascular disease allows early implementation of therapy or lifestyle modification, thereby slowing disease progression or averting catastrophic events such as a stroke or heart attack.
Appointments
Ophthalmology
Assistant ProfessorPrimaryPathology
Assistant ProfessorSecondary
Other Departments & Organizations
Education & Training
- MD
- The University of Texas Medical Branch
- PhD
- The University of Texas Medical Branch
Research
Clinical Care
Fact Sheets
Macular Degeneration
Learn More on Yale MedicineDiabetic Eye Disease
Learn More on Yale MedicineEye (Ocular) Cancer
Learn More on Yale MedicineType 2 Diabetes: Symptoms and Treatments
Learn More on Yale Medicine
Board Certifications
Ophthalmology
- Certification Organization
- AB of Ophthalmology
- Original Certification Date
- 2020
Yale Medicine News
Links & Media
News
- July 11, 2024Source: Yale Ventures
11 Yale Projects Receive Awards from the Colton Center for Autoimmunity
- May 11, 2023
Dr. Mathieu Bakhoum Receives Award for R21 Grant from the NEI for a Project of Pterygium Progression
- April 25, 2023
Mathieu Bakhoum, MD, PhD, Awarded Major Grant from the Department of Defense
- November 03, 2022
Mathieu Bakhoum, MD Recipient of Grant from Connecticut Lions Eye Research Foundation