2010
Role of ACh-GABA Cotransmission in Detecting Image Motion and Motion Direction
Lee S, Kim K, Zhou ZJ. Role of ACh-GABA Cotransmission in Detecting Image Motion and Motion Direction. Neuron 2010, 68: 1159-1172. PMID: 21172616, PMCID: PMC3094727, DOI: 10.1016/j.neuron.2010.11.031.Peer-Reviewed Original ResearchMeSH KeywordsAcetylcholineAmacrine CellsAnimalsGamma-Aminobutyric AcidMotion PerceptionPhotic StimulationRabbitsRetinaSynapsesSynaptic TransmissionConceptsDirection-selective ganglion cellsStarburst amacrine cellsGamma-aminobutyric acidGABAergic mechanismsGABAergic synapsesCholinergic inputAmacrine cellsGanglion cellsCholinergic connectionsSynaptic organizationCholinergic synapsesDirection selectivityAcetylcholineLight onsetCotransmissionMotion sensitivitySynapsesHigh levelsCellsCoreleaseVisual signalsRetina
2006
The Synaptic Mechanism of Direction Selectivity in Distal Processes of Starburst Amacrine Cells
Lee S, Zhou ZJ. The Synaptic Mechanism of Direction Selectivity in Distal Processes of Starburst Amacrine Cells. Neuron 2006, 51: 787-799. PMID: 16982423, PMCID: PMC4227911, DOI: 10.1016/j.neuron.2006.08.007.Peer-Reviewed Original ResearchConceptsStarburst amacrine cellsAmacrine cellsDistal processesSurround inhibitionDirection selectivityCurrent-clamp recordingsCenter-surround receptive field structureExcitatory synaptic inputsGABA release sitesPatch-clamp recordingsReceptive field centerRobust direction selectivityReceptive field structureSurround antagonismInhibitory inputsSynaptic mechanismsSynaptic inputsReciprocal inhibitionProlonged inhibitionStimulus motionInhibitionLight stimulationStimulationField centerCells
2004
A Developmental Switch in the Excitability and Function of the Starburst Network in the Mammalian Retina
Zheng JJ, Lee S, Zhou ZJ. A Developmental Switch in the Excitability and Function of the Starburst Network in the Mammalian Retina. Neuron 2004, 44: 851-864. PMID: 15572115, DOI: 10.1016/j.neuron.2004.11.015.Peer-Reviewed Original ResearchConceptsStarburst cellsGABAergic synapsesStarburst networkDual patch-clamp recordingsSpontaneous retinal wavesPatch-clamp recordingsVisual system developmentNicotinic synapsesNetwork excitabilityRetinal wavesRabbit retinaMammalian retinaRecurrent excitationSynapsesDependent mannerGABAExcitabilityRetinaCellsCa2Early developmentCoreleaseExcitatoryNicotinicACh