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Qin Yan, PhD

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Professor of Pathology

Titles

Co-Leader, Genomics, Genetics and Epigenetics Research Program, Yale Cancer Center; Director, Center for Epigenetics and Biomarkers, Pathology; Scientific Co-Director, Center for Breast Cancer, Yale Cancer Center

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About

Titles

Professor of Pathology

Co-Leader, Genomics, Genetics and Epigenetics Research Program, Yale Cancer Center; Director, Center for Epigenetics and Biomarkers, Pathology; Scientific Co-Director, Center for Breast Cancer, Yale Cancer Center

Biography

Dr. Qin Yan (严钦) is a Professor of Pathology at Yale Medical School and a member of Yale Comprehensive Cancer Center, Yale Stem Cell Center, Yale Center for Immuno-Oncology, and Yale Center for Research on Aging. He directs a research laboratory to elucidate the roles of epigenetic mechanisms that drive tumor initiation and progression and to translate their findings to the clinic. His laboratory has made significant contributions to the understanding of the KDM5 H3K4me3/2 histone demethylases and epigenetic regulators of immune evasion and cancer metastasis. Dr. Yan received his B.S. degree from the University of Science and Technology of China. After his Ph.D. training on regulation of transcription and ubiquitination with Drs. Joan and Ronald Conaway at the Oklahoma Medical Research Foundation and Stowers Institute for Medical Research, he completed his postdoctoral training on cancer biology with Nobel laureate Dr. William Kaelin at the Dana-Farber Cancer Institute and Harvard Medical School. He has received a number of awards including the ASIP Outstanding Investigator Award, Era of Hope Scholar Award from DoD Breast Cancer Research Program, Stewart Fellow Award and V Scholar Award.

Appointments

Education & Training

Postdoctoral Associate
Dana-Farber Cancer Institute and Howard Hughes Medical Institute (2007)
PhD
University of Oklahoma College of Medicine, Biochemistry and Molecular Biology (2002)
BS
University of Science and Technology of China, Molecular Biology (1996)

Research

Overview

Medical Subject Headings (MeSH)

Drug Resistance, Neoplasm; Epigenetic Repression; Epigenomics; Gene Expression Regulation; Immunotherapy; Jumonji Domain-Containing Histone Demethylases; Melanoma; Neoplasm Metastasis; Retroelements

Research at a Glance

Yale Co-Authors

Frequent collaborators of Qin Yan's published research.

Publications

Featured Publications

2024

2023

Academic Achievements and Community Involvement

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