Amar Patel, MD
Research & Publications
Biography
News
Research Summary
Dr. Patel's research interests include the use of deep brain stimulation in the treatment of movement disorders, in particular Parkinson's disease, tremor and dystonia. He is interested in identifying the most appropriate patient candidates for this advanced therapy, as well as determining their optimal targets and programming parameters. Dr. Patel is also involved in clinical research regarding Wilson disease, a rare genetic disease affecting copper metabolism which can cause neurological, hepatic, and psychiatric illness. He is involved in research to better understand the natural history of the illness, its neurological manifestations, and treatment trials.
Coauthors
Research Interests
Dystonia; Globus Pallidus; Movement Disorders; Neurology; Parkinson Disease; Tremor; Subthalamic Nucleus; Deep Brain Stimulation
Selected Publications
- Major Depressive Disorder in an International Multisite Wilson Disease RegistryCamarata M, Ala A, Coskun A, Deng Y, Embel V, Gonzalez-Peralta R, Maciejewski K, Patel A, Rubman S, To U, Tomlin R, Schilsky M, Zimbrean P. Major Depressive Disorder in an International Multisite Wilson Disease Registry Journal Of The Academy Of Consultation-Liaison Psychiatry 2022, 64: 106-117. PMID: 36521682, DOI: 10.1016/j.jaclp.2022.12.001.
- Mental imagery content is associated with disease severity and specific brain functional connectivity changes in patients with Parkinson’s diseaseCherry J, Kamel S, Elfil M, Aravala S, Bayoumi A, Patel A, Sinha R, Tinaz S. Mental imagery content is associated with disease severity and specific brain functional connectivity changes in patients with Parkinson’s disease Brain Imaging And Behavior 2022, 17: 161-171. PMID: 36434490, PMCID: PMC10050121, DOI: 10.1007/s11682-022-00749-z.
- P12 Effect of liver disease, neurological disease and mental health issues on quality of life in patients with wilson diseaseCamarata M, Ala A, Maciejewski K, To U, Zimbrean P, Rubman S, Coskun A, Patel A, Wadhwa A, Apdik T, Tomlin R, Deng Y, Gonzalez-Peralta R, Schilsky M. P12 Effect of liver disease, neurological disease and mental health issues on quality of life in patients with wilson disease Gut 2020, 69: a13-a13. DOI: 10.1136/gutjnl-2020-basl.23.
- P13 Major depressive disorder in patients with wilson’s disease: relationship with liver disease, neurological disease and quality of lifeCamarata M, Ala A, Maciejewski K, To U, Zimbrean P, Rubman S, Patel A, Wadhwa A, Coskun A, Apdik T, Tomlin R, Deng Y, Schilsky M. P13 Major depressive disorder in patients with wilson’s disease: relationship with liver disease, neurological disease and quality of life Gut 2020, 69: a13-a13. DOI: 10.1136/gutjnl-2020-basl.24.
- FRI303 Major depressive disorder in patients with Wilson’s disease: relationship with liver disease, neurological disease and quality of lifeCamarata M, Ala A, To U, Zimbrean P, Rubman S, Patel A, Wadhwa A, Maciejewski K, Song X, Deng Y, Tomlin R, Apdik T, Coskun A, Schilsky M. FRI303 Major depressive disorder in patients with Wilson’s disease: relationship with liver disease, neurological disease and quality of life Journal Of Hepatology 2020, 73: s550-s551. DOI: 10.1016/s0168-8278(20)31573-7.
- Deep Brain Stimulation Target Selection in Co-Morbid Essential Tremor and Parkinson’s DiseaseWadhwa A, Schaefer S, Gerrard J, Deeb W, Okun MS, Patel A. Deep Brain Stimulation Target Selection in Co-Morbid Essential Tremor and Parkinson’s Disease Tremor And Other Hyperkinetic Movements 2020, 10: 17. PMID: 32775031, PMCID: PMC7394224, DOI: 10.5334/tohm.62.
- 257 Bipolar disorder in patients with Wilson diseaseZimbrean P, Rubman S, Maciejewski K, Coskun, Nalamada K, Camarata M, Tomlin R, Patel A, To U, Ala A, Gonzalez-Peralta R, Deng Y, Schilsky M. 257 Bipolar disorder in patients with Wilson disease Journal Of Psychosomatic Research 2020, 133: 110055. DOI: 10.1016/j.jpsychores.2020.110055.
- Dorsal GPi/GPe Stimulation Induced Dyskinesia in a Patient with Parkinson’s DiseaseElkouzi A, Tsuboi T, Burns M, Eisinger R, Patel A, Deeb W. Dorsal GPi/GPe Stimulation Induced Dyskinesia in a Patient with Parkinson’s Disease Tremor And Other Hyperkinetic Movements 2019, 9 DOI: 10.5334/tohm.496.
- Major depressive disorder in patients with Wilson diseaseZimbrean P, Gold S, Nalamada K, Camarata M, Tomlin R, Patel A, Vives-Rodrigues A, Ekong U, Bramford N, Valentino P, To U, Deng Y, Song X, Ala A, Schilsky M. Major depressive disorder in patients with Wilson disease Journal Of Psychosomatic Research 2019, 121: 148. DOI: 10.1016/j.jpsychores.2019.03.145.
- Deep Brain Stimulation Management of Essential Tremor with Dystonic FeaturesPatel A, Deeb W, Okun MS. Deep Brain Stimulation Management of Essential Tremor with Dystonic Features Tremor And Other Hyperkinetic Movements 2018, 8: 557. PMID: 29971197, PMCID: PMC6026276, DOI: 10.7916/d8p85vbq.
- Deep Brain Stimulation Management of Essential Tremor with Dystonic FeaturesPatel A, Deeb W, Okun M. Deep Brain Stimulation Management of Essential Tremor with Dystonic Features Tremor And Other Hyperkinetic Movements 2018, 8: 557. DOI: 10.5334/tohm.426.
- Management of Elevated Therapeutic Impedances on Deep Brain Stimulation LeadsDeeb W, Patel A, Okun M, Gunduz A. Management of Elevated Therapeutic Impedances on Deep Brain Stimulation Leads Tremor And Other Hyperkinetic Movements 2017, 7: 493. DOI: 10.5334/tohm.370.
- Velopharyngeal Dystonia: An Unusual Focal Task-specific Dystonia?Patel A, Sulica L, Frucht S. Velopharyngeal Dystonia: An Unusual Focal Task-specific Dystonia? Tremor And Other Hyperkinetic Movements 2017, 7: 365. DOI: 10.5334/tohm.353.
- Deep Brain Stimulation Target Selection in an Advanced Parkinson’s Disease Patient with Significant Tremor and Comorbid DepressionPatel AS. Deep Brain Stimulation Target Selection in an Advanced Parkinson’s Disease Patient with Significant Tremor and Comorbid Depression Tremor And Other Hyperkinetic Movements 2017, 7: 447. PMID: 28428905, PMCID: PMC5395677, DOI: 10.7916/d8kd23nz.
- Deep Brain Stimulation Target Selection in an Advanced Parkinson’s Disease Patient with Significant Tremor and Comorbid DepressionPatel A. Deep Brain Stimulation Target Selection in an Advanced Parkinson’s Disease Patient with Significant Tremor and Comorbid Depression Tremor And Other Hyperkinetic Movements 2017, 7: 447. DOI: 10.5334/tohm.369.
- What is the pathway forward for the surgical management of essential tremor?Louis ED, Patel A, Gerrard JL. What is the pathway forward for the surgical management of essential tremor? Annals Of Neurology 2017, 81: 351-353. PMID: 28195360, PMCID: PMC5366883, DOI: 10.1002/ana.24892.
- Early Use of 60 Hz Frequency Subthalamic Stimulation in Parkinson's Disease: A Case Series and Review.Ramdhani RA, Patel A, Swope D, Kopell BH. Early Use of 60 Hz Frequency Subthalamic Stimulation in Parkinson's Disease: A Case Series and Review. Neuromodulation : Journal Of The International Neuromodulation Society 2015, 18: 664-9. PMID: 25833008, DOI: 10.1111/ner.12288.
- Isolated vocal tremor as a focal phenotype of essential tremor: a retrospective case reviewPatel A, Frucht SJ. Isolated vocal tremor as a focal phenotype of essential tremor: a retrospective case review Journal Of Clinical Movement Disorders 2015, 2: 4. PMID: 26788340, PMCID: PMC4711152, DOI: 10.1186/s40734-015-0016-5.
- Chapter 40 Myoclonus Classification, Clinical Features, and GeneticsPatel A, Frucht S. Chapter 40 Myoclonus Classification, Clinical Features, and Genetics 2015, 655-670. DOI: 10.1016/b978-0-12-405195-9.00040-8.
Clinical Trials
Conditions | Study Title |
---|---|
Diseases of the Endocrine System; Genetics - Adult | A Phase I/II Study of VTX-801 in Adult Patients With Wilson's Disease (GATEWAY) |
Genetics - Adult | Efficacy and Safety of WTX101 Administered for 48 Weeks Versus Standard of Care in Wilson Disease Subjects |
Diseases of the Digestive System - Liver; Diseases of the Eye; Diseases of the Nervous System | Wilson Disease Registry |