Vishwa Deep Dixit, DVM, PhD
Cards
About
Titles
Waldemar Von Zedtwitz Professor of Pathology and Professor of Immunobiology
Director, Yale Center for Research on Aging (Y-Age), PathologyBiography
Son of teachers, Deep grew up in Hisar (Northwest India). He studied Veterinary Medicine in India, did PhD Research in University of Hannover Germany and postdoc research in Morehouse School of Medicine and NIH. He currently holds Waldemar Von Zedtwitz endowed chair and is a Professor in the Departments of Pathology, Comparative Medicine and Immunobiology. Dixit is also the director of Yale Center for Research on Aging (Y-Age). Dixit lab studies Immunometabolism and aging. His team help establish NLRP3 inflammasome in causing ‘inflammaging’ and immunosenescence that leads to age-related chronic diseases including metabolic dysfunction. Dixit and his collaborators have identified that switch from glycolysis to ketogenesis deactivates the inflammasome and reduces immunopathology. The ongoing work in his laboratory on caloric restriction (CR) in humans (CALERIE-II trial), which extends lifespan in animal models has revealed that adaptation to negative energy balance in a host can be harnessed to identify immunometabolic CR-mimetics to improve health and potentially lifespan. Dixit lab has identified PLA2G7 and SPARC as the CR-inhibited proteins in humans that control inflammation and healthspan in mouse models.
Appointments
Pathology
ProfessorPrimaryImmunobiology
ProfessorSecondaryComparative Medicine
ProfessorSecondary
Other Departments & Organizations
- Cancer Immunology
- Comparative Medicine
- Diabetes Research Center
- Dixit Lab
- Immunobiology
- Immunology
- Pathology
- Yale Cancer Center
- Yale Center for Molecular and Systems Metabolism (YMSM)
- Yale Center for Research on Aging (Y-Age)
- Yale Combined Program in the Biological and Biomedical Sciences (BBS)
- Yale Ventures
- Yale-UPR Integrated HIV Basic and Clinical Sciences Initiative
Education & Training
- Visiting Fellow and Research Fellow
- National Institute on Aging, NIH (2006)
- PhD
- Haryana Agricultural University (2000)
- PhD
- Research completed in University of Hannover (2000)
- MS
- Haryana Agricultural University (1999)
- DVM
- Haryana Agricultural University (1994)
Research
Academic Achievements and Community Involvement
Links & Media
Media
News
- June 24, 2024
What Causes the Aging Process?
- March 06, 2024
New Frontiers in Obesity Research at Yale
- October 02, 2023
New Yale Initiative Looks Beyond Life Span to Increase Years of Health
- February 26, 2023
Deadline Looms as SenNet Program at Yale Seeks Underrepresented Students for Summer Internships