Jun Liu, PhD

Dr. Liu has been working in the field of electron microscopy for 20 years. In particular, he gained expertise in cryo-electron tomography (cryo-ET) after working with Prof. Ken Taylor at Florida State University and Dr. Sriram Subramaniam at NIH. Since he started his own laboratory in 2007, he has been dedicated to developing high-throughput cryo-ET pipeline in which both data collection and image analysis are streamlined and automated. The high-throughput cryo-ET pipeline is becoming increasingly powerful, enabling his laboratory to visualize over 100,000 cells from 100 different bacterial species. More importantly, the massive data from cryo-ET has been systematically utilized to gain structural insights into fundamental biological processes related to signaling transduction, flagellar assembly, protein secretion, phage adsorption DNA translocation, and host-pathogen interactions. Dr. Liu has published more than 60 papers in journals that include Nature, Science, PNAS, and Cell.