High-Throughput Cryo-ET
The Liu laboratory is dedicated to developing a high-throughput cryo-electron tomography (cryo-ET) pipeline for high-resolution structure determination of molecular machines in cells. Our state-of-the-art imaging system has been utilized to gain molecular insights into fundamental biochemical processes: bacterial motility, chemotactic signaling, protein secretion, and DNA translocation.
Molecular Machines in Cells
Cryo-electron tomography reveals cellular architecture of Treponema pallidum
Video by Jun Liu00:00:37
Molecular mechanism for rotational switching of the bacterial flagellar motor
Video by Yunjie Chang, Kai Zhang, Brittany L. Carroll, Xiaowei Zhao, Nyles W. Charon, Steven J. Norris, Md A. Motaleb, Chunhao Li & Jun Liu
Twitter Feed
@JunLiuLabCongratulations to former @JunLiuLab member Meng Shao on her new position @Westlake_Uni #Hangzhou! We miss you and wish you great success!15 HOURS AGO
@JunLiuLab Retweeted @PresMcCulloughIt was an honor to welcome international researchers to the Kenneth A. Taylor Symposium on Cryo-EM and Muscle Biology hosted by the FSU Institute of Molecular Biophysics. https://t.co/tH71mGUree https://t.co/c53si7g54x2 DAYS AGO
@JunLiuLab Retweeted @microbelab#Gratitude @americanacad Seven Yale faculty members elected to American Academy of Arts and Sciences https://t.co/eJFSh7zbKs17 DAYS AGO
@JunLiuLabA wonderful #labsocial to celebrate our amazing Donghyun (Raphael) Park @RaphaelPark7 completing his #PhD #YaleMed and postgrad Yue Lin (Cedric) Hu accepted to #medschool #medstudent! Congratulations! https://t.co/atAk0yorDv17 DAYS AGO
@JunLiuLabThanks to @YaleMed for highlighting great work by @PhilGuo1 in @JunLiuLab published in @PNASNews Bacteria Swim: Yale Researchers Discover New Mechanisms https://t.co/r7CmAtnShl via @yalemed #Borrelia #bacteria #flagella #cryoETHow2 MONTHS AGO