High-Throughput Cryo-ET
The Liu laboratory is dedicated to developing a high-throughput cryo-electron tomography (cryo-ET) pipeline for high-resolution structure determination of molecular machines in cells. Our state-of-the-art imaging system has been utilized to gain molecular insights into fundamental biochemical processes: bacterial motility, chemotactic signaling, protein secretion, and DNA translocation.
Molecular Machines in Cells
Cryo-electron tomography reveals cellular architecture of Treponema pallidum
Video by Jun Liu00:00:37
Molecular mechanism for rotational switching of the bacterial flagellar motor
Video by Yunjie Chang, Kai Zhang, Brittany L. Carroll, Xiaowei Zhao, Nyles W. Charon, Steven J. Norris, Md A. Motaleb, Chunhao Li & Jun Liu
Twitter Feed
A wonderful review by our @ChangYunjie
#FlagellarMotor @CellPressNews Structural basis of bacterial flagellar motor rotation and switching https://t.co/OGXhDKEzbl2 DAYS AGO
Cell wall is mostly finished on the E. coli painting. Jumping into the nucleoid now. https://t.co/H77cVoVA64A MONTH AGO
Our thanks and best wishes to former @JunLiuLab member @BritCarroll2 as she embarks on new discoveries #McGill https://t.co/j4HZbQ7Api https://t.co/hk6LCdaOKlA MONTH AGO
Great paper from former @microbelab Groisman lab member Jinki Yeom, Asst Prof SNUCM, revealing how protein preservation speeds growth recovery #bacterialgrowth #microbes https://t.co/iKFGGDjaaU
https://t.co/P6P54McXBe3 MONTHS AGO
Great talks at the Virtual Conference on Prokaryotic Small Proteins by Nora Vazquez-Laslop @thisisUIC and Rotem Sorek @WeizmannScience. Lots of productive discussions #smallproteins https://t.co/Mrm7fSNIDw3 MONTHS AGO