Ania Jastreboff, MD, PhD
Associate Professor of Medicine (Endocrinology); Director, Weight Management & Obesity Prevention; Medical Director, Yale Stress Center
Biography
Research & Publications
Patient Care
News
Locations
Appointments
Biography
Dr. Jastreboff is an Obesity Medicine physician-scientist, board certified in adult Endocrinology and Metabolism, Pediatric Endocrinology, and Obesity Medicine. She is nationally and internationally recognized in the Obesity Medicine field for developing Clinical Practice Guidelines (2016) for The Comprehensive Care of Patients with Obesity (AACE/ACE), serving on the Board of Directors for the American Board of Obesity Medicine (ABOM), educating the next generation of Obesity Medicine physicians by teaching annually at Harvard Blackburn Treating Obesity course and the Columbia/Cornell Obesity course, and conducting cutting-edge clinical translational obesity research. Her research includes both large, multi-center clinical outcomes trials using anti-obesity medication as well as neuroimaging studies (fMRI and PET) examining the neurobiology underlying obesity and the mechanisms of anti-obesity medications. Recently, Dr. Jastreboff served as the lead author on the SURMOUNT-1 trial investigating novel GIP/GLP-1 receptor agonist, tirzepatide, for the treatment of obesity (Jastreboff, et al., NEJM, 2022).
Clinically, Dr. Jastreboff specializes in sophisticated use of anti-obesity medication combinations to help patients reach their weight and health goals. She mainly sees patients for obesity treatment and weight management and additionally cares for patients with prediabetes and diabetes.
Dr. Jastreboff is board certified in Internal Medicine, Pediatrics, Endocrinology and Metabolism, Pediatric Endocrinology, and Obesity Medicine.
She completed her PhD at Yale University's Investigative Medicine Program focused on clinical translational investigation with a dissertation entitled “Neural Response to Food Cues and Stress in Individuals with Obesity".
Dr. Jastreboff's research is supported by NIH/NIDDK (R01s) and industry funded global, multi-center clinical trials.
Education & Training
- Clinical Research ScholarYale University School of Medicine (2013)
- PhDYale University Graduate School of Arts and Sciences (2011)
- Endocrinology Postdoctoral FellowshipYale University (2011)
- Pediatric Endocrinology Postdoctoral FellowshipYale University (2011)
- Chief ResidentUniversity of Maryland (2006)
- ResidencyUniversity of Maryland School of Medicine (2006)
- MDUniversity of Maryland at Baltimore (2002)
- BABucknell University, Art History (1998)
Activities
- Pharmacotherapy for the treatment of adolescents with obesitySantiago, Santiago Metropolitan Region, Chile 2020Pharmacotherapy for the treatment of adolescents with obesity
- Pharmacotherapy for the treatment of adolescent obesity: Where are we now? Where are we going?Rio de Janeiro, RJ, Brazil 202034th Brazilian Congress of Endocrinology and Metabolism
- Obesity PharmacotherapyBoston, MA, United States 2020Obesity Pharmacotherapy
- Overcoming barriers to use of anti-obesity pharmacotherapyBoston, MA, United States 2020Overcoming barriers to use of anti-obesity pharmacotherapy
- Pharmacotherapy for the treatment of adolescents with obesityCleveland, OH, United States 2020Pharmacotherapy for the treatment of adolescents with obesity
- Pharmacotherapy for the treatment of adolescents with obesity: Where are we now? Where are we going?Worcester, MA, United States 2020Pharmacotherapy for the treatment of adolescents with obesity: Where are we now? Where are we going?
- Pharmacological treatment of adolescents with obesitySan Francisco, CA, United States 2020Pharmacological treatment of adolescents with obesity
- The best strategy for diabetes remission using obesity treatments is... pharmacotherapyChicago, IL, United States 2020The best strategy for diabetes remission using obesity treatments is... pharmacotherapy
- Teenage Brains on Sugar: Neural Response to Monosaccharide Ingestion in Adolescent Obesity.Rio de Janeiro, RJ, Brazil 2020Teenage Brains on Sugar: Neural Response to Monosaccharide Ingestion in Adolescent Obesity.
- Obesity Pharmacotherapy Workshops and Meet the ExpertBoston, MA, United States 2020Obesity Pharmacotherapy Workshops and Meet the Expert
- Hold ‘em or Draw? Pharmacological Treatment on Adolescents with ObesityLas Vegas, NV, United States 2019Hold ‘em or Draw? Pharmacological Treatment on Adolescents with Obesity
- Obesity PharmacotherapyBoston, MA, United States 2019Obesity Pharmacotherapy
- Overcoming Barriers to use of Anti-Obesity PharmacotherapyBoston, MA, United States 2019Overcoming Barriers to use of Anti-Obesity Pharmacotherapy
- Neuroimaging and Modulation in Obesity and Diabetes ResearchBethesda, MD, United States 2019Neuroimaging and Modulation in Obesity and Diabetes Research
- Teenage Brains on Sugar: Neural Response to Monosaccharide Ingestion in Adolescent ObesityNew York, NY, United States 2019Teenage Brains on Sugar: Neural Response to Monosaccharide Ingestion in Adolescent Obesity
- Obesity Pathophysiology: the role of the brainNew York, NY, United States 2019Obesity Pathophysiology: the role of the brain
- Pharmacologic Treatment of ObesityLas Vegas, NV, United States 2019Pharmacologic Treatment of Obesity
- Treating patients with Diabetes and Obesity: the Role of Bariatric Surgery and PharmacotherapyLedyard, CT, United States 2019Treating patients with Diabetes and Obesity: the Role of Bariatric Surgery and Pharmacotherapy
- Obesity is Highly Prevalent Among Patients Admitted to an Emergency Department Chest Pain Observation Unit.Las Vegas, NV, United States 2019Obesity is Highly Prevalent Among Patients Admitted to an Emergency Department Chest Pain Observation Unit.
- Obesity Is Highly Prevalent among Patients Admitted to an Emergency Department Chest Pain Observation UnitLas Vegas, NV, United States 2019Obesity Is Highly Prevalent among Patients Admitted to an Emergency Department Chest Pain Observation Unit
- Does Hyperinsulinemia in Obesity Elicit Brain Responses that Provoke Greater Motivation for Food?Bethesda, MD, United States 2019Does Hyperinsulinemia in Obesity Elicit Brain Responses that Provoke Greater Motivation for Food?
- Obesity Is Associated with Reduced 11-beta-Hydoxysteroid Dehydrogenase Type I Levels in the Human BrainBethesda, MD, United States 2019Obesity Is Associated with Reduced 11-beta-Hydoxysteroid Dehydrogenase Type I Levels in the Human Brain
- Investigating GLP-1 Agonism for Blocking Cocaine Euphoria and Self-AdministrationOrlando, FL, United States 2019Investigating GLP-1 Agonism for Blocking Cocaine Euphoria and Self-Administration
- Mindfulness based stress reduction for older couples with metabolic syndromeVancouver, BC, Canada 2019Mindfulness based stress reduction for older couples with metabolic syndrome
- Characterizing Obesity and Outcomes among Emergency Department Patients Admitted to a Chest Pain Observation UnitWorcester, MA, United States 2019Characterizing Obesity and Outcomes among Emergency Department Patients Admitted to a Chest Pain Observation Unit
- Obesity Pharmacotherapy Workshops and Meet the ExpertBoston, MA, United States 2019Obesity Pharmacotherapy Workshops and Meet the Expert
- Pharmacologic Treatment of ObesityPhoenix, AZ, United States 2018Pharmacologic Treatment of Obesity
- Obesity Pharmacotherapy Workshops and Meet the ExpertBoston, MA, United States 2018Obesity Pharmacotherapy Workshops and Meet the Expert
- Special Considerations in Use of Hybrid Closed LoopCharlotte, NC, United States 2018Special Considerations in Use of Hybrid Closed Loop
- Teenage Brains of Sugar: Neural Responses to Monosaccharide Ingestion in Adolescent ObesityIowa City, IA, United States 2018Obesity Physiology and Genetics
- Special Considerations in Use of Hybrid Closed LoopFort Lauderdale, FL, United States 2018Special Considerations in Use of Hybrid Closed Loop
- Obesity Physiology and GeneticsNew York, NY, United States 2018Obesity Physiology and Genetics
- Hyperinsulinemia Invokes Greater Cerebral Blood Flow in Reward and Motivation Regions in ObesityOrlando, FL, United States 2018Hyperinsulinemia Invokes Greater Cerebral Blood Flow in Reward and Motivation Regions in Obesity
- Reduction of 11β-hydroxysteroid dehydrogenase type 1 enzyme levels with increasing body mass index: A Brain PET imaging studyPhiladelphia, PA, United States 2018Reduction of 11β-hydroxysteroid dehydrogenase type 1 enzyme levels with increasing body mass index: A Brain PET imaging study
- Obesity is associated with reduced 11β-Hydroxysteroid Dehydrogenase Type 1 levels in the Human BrainChicago, IL, United States 2018Obesity is associated with reduced 11β-Hydroxysteroid Dehydrogenase Type 1 levels in the Human Brain
- Severe Hypercalemia and acute pancreatitis in a postpartum womanBoston, MA, United States 2018Severe Hypercalemia and acute pancreatitis in a postpartum woman
- Hedonic Eating/Food Reward and Appetite Regulation and then Development of Severe Adolescent Obesity in AdolescentsBethesda, MD, United States 2017Developing Precision Medicine Approaches to the Treatment of Severe Obesity in Adolescents
- Obesity Medicine: a new frontierButler, PA, United States 2017Obesity Medicine: a new frontier
- Obesity Pharmacotherapy Workshops and Meet the ExpertBoston, MA, United States 2017Obesity Pharmacotherapy Workshops
- Special Considerations in Use of Hybrid Closed LoopNew Haven, CT, United States 2017Special Considerations in Use of Hybrid Closed Loop
- Obesity Physiology and GeneticsNew York, NY, United States 2017Obesity Physiology and Genetics
- Hedonic Eating/Food Reward and Appetite Regulation and the Development of Severe Obesity in AdolescentsBethesda, MD, United States 2017Hedonic Eating/Food Reward and Appetite Regulation and the Development of Severe Obesity in Adolescents
- Does Hyperinsulinemia in Obesity Elicit Brain Responses that Provoke Greater Motivation for Food?San Diego, CA, United States 2017Does Hyperinsulinemia in Obesity Elicit Brain Responses that Provoke Greater Motivation for Food?
- Preventing childhood obesity through a mindfulness-based parenting intervention for stress reductionWashington, DC, United States 2017Preventing childhood obesity through a mindfulness-based parenting intervention for stress reduction
- Lower insulin sensitivity with increasing BMI is associated with greater high-calorie food intakeWashington, DC, United States 2017Lower insulin sensitivity with increasing BMI is associated with greater high-calorie food intake
- Neural Response to Glucose Ingestion in Obese AdolescentsKatowice, Silesian Voivodeship, Poland 2016The Polish Society of Endocrinology, 21st Congress
- Obesity Pharmacotherapy Workshops and Meet the ExpertBoston, MA, United States 201629th Annual Blackburn Course in Obesity Medicine
- Cushing's disease: The case of whipped cream cloudsBoston, MA, United States 2016Obesity Medicine Interhospital Rounds
- AACE/ACE Comprehensive Clinical Practice Guidelines for the Medical Care of Patients with Obesity - Benefits of weight loss therapyOrlando, FL, United States 2016American Association of Clinical Endocrinologists (AACE) annual meeting
- Preventing Childhood Obesity through a Family-Based Mindfulness InterventionBethesda, MD, United States 2016Preventing Childhood Obesity through a Family-Based Mindfulness Intervention
- Obesity Medicine: A New FrontierAlbany, NY, United States 2016Obesity Medicine: A New Frontier
- Glucose Ingestion: Are Adolescents Different From Adults?Vancouver, BC, Canada 2015International Diabetes Federation
- Relationship between insulin resistance, brain activity, and prospective weight gainBoston, MA, United States 2015Relationship between insulin resistance, brain activity, and prospective weight gain
- Agonism for Blocking Cocaine Euphoria and Self-AdministrationWashington, DC, United States 2015Agonism for Blocking Cocaine Euphoria and Self-Administration
- Neural correlates of food-cue-induced food craving in obesity: association with insulin resistanceBethesda, MD, United States 2013NIH/NIDDK Intramural Program
- Response to Food Cues in Obese and Lean AdolescentsChicago, IL, United States 2013Response to Food Cues in Obese and Lean Adolescents
- Neural Response to Food Cues and Stress in Obese IndividualsBaltimore, MD, United States 2010Neural Response to Food Cues and Stress in Obese Individuals
- Running: The Good, the Bad, and the Not So UglyBaltimore, MD, United States 2006Running: The Good, the Bad, and the Not So Ugly
- Pediatric Obesity in Old Order AmishBaltimore, MD, United States 2006Pediatric Obesity in Old Order Amish
Honors & Recognition
| Award | Awarding Organization | Date |
|---|---|---|
| Young Physician-Scientist Award | American Association for Clinical Investigation (ASCI) | 2013 |
| First Place Poster Award, Yale Multi-Disciplinary Endocrinology & Metabolism Retreat | Yale Univeristy | 2013 |
| American Diabetes Association Young Investigator Travel Grant Award | American Diabetes Association (ADA) | 2013 |
| Burroughs Wellcome Fund Travel Award, Translational Science Meeting 2013 | Burroughs Wellcome Fund | 2013 |
| Translational Science Poster Award | Association for Clinical Research Training and Society for Clinical and Translational Science | 2013 |
| Diabetes Endocrinology Research Center (DRC), Poster Awardee | Yale University | 2011 |
| Yale Pediatric Fellows’ Research Day, Oral presentation award winner | Yale University | 2011 |
Professional Service
| Organization | Role | Date |
|---|---|---|
| WTNH (Channel 8) | WTNH (Channel 8) On Call: Keto Diet – TV interview on news station: https://www.wtnh.com/news/health/news-8-on-call-keto-diet/ | 2020 |
| WTNH (Channel 8) | WTNH (Channel 8). Top 3 dieting trends of 2020. Live TV interview on news station: https://www.wtnh.com/on-air/gmct-at-nine/top-3-dieting-trends-of-2020/ | 2020 |
| Better Health | Better Health. 12 diets you should never try, according to health experts. https://www.eatthis.com/unhealthiest-diets-experts/ | 2019 |
| Better Health | Better Health. Healthy gifts that are doctor recommended. https://www.eatthis.com/healthy-gifts/ | 2019 |
| WTNH (Channel 8) | WTNH (Channel 8) On Call: New policy for children with severe obesity – TV interview on news station: https://www.wtnh.com/lifestyle/health-news/news-8-on-call-new-policy-for-children-with-severe-obesity/ | 2019 |
| Huffington Post | Huffington Post. This is your body on Keto. https://www.huffpost.com/entry/keto-effects-body_l_5d9b58abe4b099389803e441 | 2019 |
| Health Central | Health Central. When diet and exercise aren’t enough. https://www.healthcentral.com/article/obesity-treatments | 2019 |
| WTNH (Channel 8) | WTNH (Channel 8) Dealing with Diabetes on Campus – Live TV interview on news station: https://www.wtnh.com/on-air/dealing-with-diabetes-on-campus/ | 2019 |
| ADA (American Diabetes Association) | Obesity/Pathogenesis of Obesity Subcommittee | 2019 - Present |
| NIH | NIH Study Section ad hoc reviewer KNOD: Kidney, Nutrition, Obesity, and Diabetes | 2019 |
| The Endocrine Society | Hormone Health Network (HHN) committee | 2019 - Present |
| NPR | National Public Radio (NPR) live interview on Where We Live with David Deroches and Lydia Brown: America’s Diet Craving. http://www.wnpr.org/post/americas-diet-craving | 2018 |
| The Obesity Society | Clinical Committee | 2018 - Present |
| MedPage Today | MedPage Today: Progress in Type 2 Diabetes Care – interview (videos): (1) Treating the Root Cause: Obesity Medicine: https://www.medpagetoday.com/resource-centers/progress-in-type-2-diabetes-care/obesity-medicine/19 (2) How Effective is Weight Loss as Therapy for Type 2 Diabetes? https://www.medpagetoday.com/resource-centers/progress-in-type-2-diabetes-care/weight-loss-as-therapy-for-type-2-diabetes/3 (3) Diets in Diabetes: One Size Doesn’t Fit All: ): https://www.medpagetoday.com/resource-centers/progress-in-type-2-diabetes-care/diet-in-diabetes/22 (4) Beating the Set Point and Maintaining Weight Loss: https://www.medpagetoday.com/resource-centers/progress-in-type-2-diabetes-care/maintaining-weight-loss/20 (5) Potential Risks of Anti-obesity Medications in Patients with T2D: https://www.medpagetoday.com/resource-centers/progress-in-type-2-diabetes-care/potential-risks-of-anti-obesity-medications/21 | 2017 |
| Department of Chronic Disease Epidemiology | Faculty Search Committee | 2017 - 2018 |
| American Association of Clinical Endocrinology (AACE) and American College of Endocrinology | AACE 2nd Consensus Conference on Obesity Writing Task Force | 2017 - 2018 |
| NIH | NIH Study Section ad hoc reviewer PRDP: Psychosocial Risk and Disease Prevention | 2017 |
| The Obesity Society | Grant Reviewer (Scientific Review Committee) | 2017 - Present |
| The Obesity Society | co-chair neuroimaging program planning committee 2019-2020, committee member 2016-present | 2016 - 2020 |
| Yale Medicine | Yale Medicine: Why Obesity is a Disease – interview (video) Obesity is a growing epidemic in America. Ania Jastreboff, MD, PhD discusses why obesity is a disease with biological underpinnings. In addition, she discusses treatment options and medications. https://www.yalemedicine.org/conditions/why-obesity-is-a-disease/ | 2016 |
| American Association of Clinical Endocrinology (AACE) and American College of Endocrinology | Task Force for the development of Clinical Practice Guidelines for the Comprehensive Medical Care of Patients with Obesity | 2015 - 2016 |
| The Obesity Society | Obesity Medicine Fellowship Curriculum Development Committee | 2015 - 2016 |
| The Obesity Society | Development of "Contributors to Obesity" infographic for organizational use and the Surgeon General (Committee) | 2015 |
| American Association of Clinical Endocrinology (AACE) and American College of Endocrinology | Task Force for the Obesity Algorithm | 2015 - 2016 |
Departments & Organizations
- Center for Weight Management
- Diabetes Center
- Diabetes Program
- Diabetes Research Center
- Endocrinology
- Internal Medicine
- Obesity Research Working Group
- Pediatric Endocrinology & Diabetes
- Pediatric Weight Solutions Program
- Status of Women in Medicine Committee (SWIM)
- Yale Medicine
- Yale Stress Center