Adjunct Faculty
Adjunct faculty typically have an academic or research appointment at another institution and contribute or collaborate with one or more School of Medicine faculty members or programs.
Adjunct rank detailsMichael Cowley, PhD
About
Research
Publications
2025
The metabolic and cardiovascular effects of amphetamine are partially mediated by the central melanocortin system
Simonds S, Pryor J, Lam B, Dowsett G, Mustafa T, Munder A, Elysee K, Balland E, Cowley L, Yeo G, Lawrence A, Spanswick D, Cowley M. The metabolic and cardiovascular effects of amphetamine are partially mediated by the central melanocortin system. Cell Reports Medicine 2025, 6: 101936. PMID: 39914386, PMCID: PMC11866487, DOI: 10.1016/j.xcrm.2025.101936.Peer-Reviewed Original ResearchConceptsEffects of amphetamineCentral melanocortin systemCardiovascular effectsMelanocortin systemFood intakeInhibition of POMC neuronsAMPH-induced anorexiaMelanocortin 4 receptor-deficientNoradrenergic neurotransmitter systemsHeart rateBrown adipose tissueElevated blood pressureBody weightNoradrenergic inhibitionPOMC neuronsAMPH-inducedSerotonergic activityPresynaptic mechanismsNeurotransmitter systemsMC4R pathwayAmphetamineBlood pressureCardiovascular functionIncreased brown adipose tissueAdipose tissue
1999
Estrogen Transiently Increases Delayed Rectifier, Voltage-Dependent Potassium Currents in Ovine Gonadotropes
Cowley M, Chen C, Clarke I. Estrogen Transiently Increases Delayed Rectifier, Voltage-Dependent Potassium Currents in Ovine Gonadotropes. Neuroendocrinology 1999, 69: 254-260. PMID: 10207277, DOI: 10.1159/000054426.Peer-Reviewed Original ResearchConceptsK+ current densityK+ currentEffects of ENystatin-perforated whole-cell recordingLH release in vitroVoltage-dependent potassium currentsResponse to gonadotropin-releasing hormoneDelayed rectifier K+ channelsWhole-cell recordingsVoltage clamp modeE treatmentRectifying K+ channelsResponse to GnRHGonadotropin-releasing hormoneRelease in vitroPre-treatment levelsVehicle-treated cellsOvine gonadotropesOutward currentDelayed RectifierPotassium currentK+ channelsPituitary cellsVoltage-dependentTreatment of cells