Developing Novel Strategies for CNS Repair and Protection
We are actively exploring a broad range of treatment strategies for the protection and repair of the central nervous system in spinal cord injury, multiple sclerosis, and stroke. These strategies include cell transplantation approaches, as well as delivery of cell products, antibodies, small molecules, and biomaterials. Using our expertise in cell isolation, transplantation, behavioral recovery assessment, and quantitative morphological analysis of tissues, are rigorously analyzing the therapeutic potentials and risks of different treatment approaches. Many of these studies are being carried out in collaborations around the world. Our emphasis has been on preclinical studies designed to provide the kinds of information necessary for assessing the feasibility of producing clinically significant improvements in patient function and for choosing the appropriate treatment parameters for clinical trials if the data suggests they are warranted.