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Pain is a pervasive symptom encountered by physicians worldwide and a longstanding medical challenge, particularly against the backdrop of the opioid crisis.
- August 03, 2023Source: The New England Journal of Medicine
Some types of pain have proven resistant to all available medications. In this episode of “Intention to Treat,” Rachel Gotbaum talks with a patient with neuropathic pain and a researcher exploring new sodium-channel blockers that offer promise for such patients.
- August 03, 2023Source: The New England Journal of Medicine
This editorial describes the science behind clinical trials of an inhibitor of the sodium channel Nav1.8 to treat acute postoperative pain.
- February 16, 2022
A team of researchers—including Yale School of Medicine’s Sulayman D. Dib-Hajj, PhD, senior research scientist in neurology, Stephen G. Waxman, MD, PhD, professor of neurology, and Lakshmi Bangalore, PhD, lecturer in neurology—has been awarded funding through the NIH HEAL Initiative: Team Research for Initial Translational Efforts in Non-addictive Analgesic Therapeutics Development.
- February 21, 2021Source: Yale News
Intravenous injection of bone marrow derived stem cells (MSCs) in patients with spinal cord injuries led to significant improvement in motor functions, researchers from Yale University and Japan report Feb. 18 in the Journal of Clinical Neurology and Neurosurgery.
- October 23, 2019
Scientists at Yale School of Medicine and Veterans Affairs Connecticut Healthcare System show at single-molecule resolution how nerve cells build their electrically excitable membranes.
- December 04, 2018
Scientists at the Yale School of Medicine and Veterans Affairs Connecticut Healthcare System have successfully demonstrated that it is possible to pinpoint genes that contribute to inter-individual differences in pain.
- November 03, 2018
The Society for Neuroscience (SfN) has announced that Stephen G. Waxman, MD, PhD, Bridget M. Flaherty Professor of Neurology and professor of neurobiology and of pharmacology, is this year's recipient of its Julius Axelrod Prize.
- April 18, 2017Source: Wired
On a scale of 1 to 10, how would you rate your pain? Would you say it aches, or would you say it stabs? Does it burn, or does it pinch?
- October 13, 2016Source: Yale Medicine
This is just one example of how Yale School of Medicine researchers and clinicians are pursuing innovations that could both improve treatment of opioid addiction and introduce new painkillers that are effective yet not addictive.