Colón-Ramos Awarded Landis Mentoring Award
Daniel A. Colón-Ramos, PhD, associate professor of neuroscience and cell biology, has been selected for the Landis Award for Outstanding Mentorship, a new annual award from the National Institute of Neurological Disorders and Stroke (NINDS) at the National Institutes of Health (NIH).
Function of gene mutations linked to neurological diseases identified
Several gene mutations have been linked to Parkinson’s disease, but exactly how and where some of them cause their damage has been unclear. A new Yale study, published in The Journal of Cell Biology, shows that one of the genes whose mutations are responsible for a familial form of Parkinson’s encodes a protein that controls the transfer of lipids between membranes of cell organelles.
Action of ‘molecular bouncers’ captured at model of nuclear membrane
DNA is packaged tightly within the cell’s nuclear membranes, which contain channels that regulate the transit of macromolecules governing all of life’s functions. Yale University researchers have built a nanoscale replica of this channel and have visualized the interaction of proteins that act as “molecular bouncers,” controlling access to the channel’s 40-nanometer entrance.
Unlocking the promise of stem cells
Haifan Lin has been a leader in stem cell research since its infancy. In just over a decade since he arrived at Yale to found the university’s Stem Cell Center, the center has grown from just a pair of labs to more than 40. Lin and his team are closing in on what they hope will be major breakthroughs in the clinical application of stem cells.
Cellular garbage collectors implicated in development of Alzheimer’s
Lysosomes are cellular sanitation engineers that help clean up and recycle internal debris no longer needed by cells. So why do researchers find so many lysosomes within the neuronal projections surrounding amyloid plaques, a hallmark of Alzheimer’s Disease brain pathology?
Dr. Fred Gorelick designated the Binder Professor of Internal Medicine
Dr. Fred Sanford Gorelick, newly designated as the Henry J. and Joan W. Binder Professor of Internal Medicine, focuses his research on the mechanisms that initiate pancreatitis, a severe inflammatory disease that causes death in up to 5% of patients.
Looking Beyond the Individual: Reflections on E.E. Just and How Academic Institutions Shape Scientific Careers
This President’s Column is by guest columnist Daniel Colón-Ramos, recipient of the 2016 E.E. Just Award from the ASCB and associate professor of Cell Biology and Neuroscience at Yale University.
James Rothman appointed Sterling Professor of Cell Biology
James E. Rothman, newly appointed as a Sterling Professor of Cell Biology, is one of the world's most distinguished biochemists and cell biologists. For his work on how molecular messages are transmitted inside and outside of human cells, he was awarded a Nobel Prize in 2013.
Six faculty elected to Connecticut Academy of Science and Engineering
Six Yale School of Medicine researchers have been elected to the prestigious Connecticut Academy of Science and Engineering (CASE), including: Alison P. Galvani, Jonathon Howard, Ann Kurth, Frederick J. Sigworth, Hugh S. Taylor, and Sandra Wolin.
Five young Yale scientists recognized for excellence
Five Yale faculty members are among the 84 young researchers designated as Faculty Scholars under a new program to promote early career scientists, launched by the Howard Hughes Medical Institute, the Simons Foundation, and the Bill and Melinda Gates Foundation.
Haifan Lin appointed the Eugene Higgins Professor of Cell Biology
Haifan Lin, newly named as the Eugene Higgins Professor of Cell Biology, is an internationally renowned stem cell biologist who directs the Yale Stem Cell Center, which serves as both an incubator for scientific discovery and a training ground for new investigators.
Yale’s James Rothman shares 2013 Nobel Prize in Physiology or Medicine
James E. Rothman, ’71 B.S., the Fergus F. Wallace Professor of Biomedical Sciences, and professor and chair of the Department of Cell Biology at Yale University, was awarded the 2013 Nobel Prize in Physiology or Medicine for his work on how molecular messages are transmitted inside and outside of our cells, the Royal Swedish National Academy announced today (Oct.7).
A precise architecture, maintained as neurons grow
Nerve cells make their connections at junctions called synapses, following a precise architecture that is mostly laid out early in development. But how do the synapses maintain their correct positions as the animal grows? Yale scientists have produced the first evidence that this process relies on glial cells and identified a novel molecular pathway that could be linked in humans to neurological disease.