Zhouping Hong
Graduate Student, Yale Combined Program in the Biological and Biomedical Sciences (BBS)About
Research
Publications
2024
Spartin-mediated lipid transfer facilitates lipid droplet turnover
Wan N, Hong Z, Parson M, Korfhage J, Burke J, Melia T, Reinisch K. Spartin-mediated lipid transfer facilitates lipid droplet turnover. Proceedings Of The National Academy Of Sciences Of The United States Of America 2024, 121: e2314093121. PMID: 38190532, PMCID: PMC10801920, DOI: 10.1073/pnas.2314093121.Peer-Reviewed Original Research
2022
Mitoguardin-2–mediated lipid transfer preserves mitochondrial morphology and lipid droplet formation
Hong Z, Adlakha J, Wan N, Guinn E, Giska F, Gupta K, Melia TJ, Reinisch KM. Mitoguardin-2–mediated lipid transfer preserves mitochondrial morphology and lipid droplet formation. Journal Of Cell Biology 2022, 221: e202207022. PMID: 36282247, PMCID: PMC9597353, DOI: 10.1083/jcb.202207022.Peer-Reviewed Original ResearchConceptsEndoplasmic reticulumLipid dropletsProtein-mediated transferLipid transport proteinsLipid droplet formationLD biologyMitochondrial proteinsSecretory pathwayMass spectrometry analysisTerminal domainMitochondrial morphologyTransport proteinsLipid transportersCellular membranesLD metabolismMembrane contactX-ray structureSpectrometry analysisOrganellesGlycerophospholipidsProteinHydrophobic cavityFatty acidsLipidsMembraneStructural and biochemical insights into lipid transport by VPS13 proteins
Adlakha J, Hong Z, Li P, Reinisch KM. Structural and biochemical insights into lipid transport by VPS13 proteins. Journal Of Cell Biology 2022, 221: e202202030. PMID: 35357422, PMCID: PMC8978259, DOI: 10.1083/jcb.202202030.Peer-Reviewed Original ResearchConceptsIntegral membrane proteinsVPS13 proteinsMembrane proteinsLipid transport proteinsPeptide recognition motifsProtein-mediated transportHuman VPS13AOrganellar membranesCytosolic leafletPro motifAcceptor organelleBiochemical insightsRecognition motifTransport proteinsContact sitesScramblasesLipid transportMembrane leafletProteinOrganellesMotifSuch receptorsLipidsSame siteVps13
2017
A DNA Origami Mechanical Device for the Regulation of Microcosmic Structural Rigidity
Wan N, Hong Z, Wang H, Fu X, Zhang Z, Li C, Xia H, Fang Y, Li M, Zhan Y, Yang X. A DNA Origami Mechanical Device for the Regulation of Microcosmic Structural Rigidity. Small 2017, 13 PMID: 28902974, DOI: 10.1002/smll.201700866.Peer-Reviewed Original Research