2020
Transcriptomic responses to hypoxia in endometrial and decidual stromal cells
Rytkönen KT, Heinosalo T, Mahmoudian M, Ma X, Perheentupa A, Elo LL, Poutanen M, Wagner G. Transcriptomic responses to hypoxia in endometrial and decidual stromal cells. Reproduction 2020, 160: 39-51. PMID: 32272449, DOI: 10.1530/rep-19-0615.Peer-Reviewed Original ResearchConceptsDecidual stromal cellsEndometrial stromal fibroblastsEndometriotic stromal cellsStromal cellsInflammatory transcription factorsEpithelial-mesenchymal transitionExpression of JunDCEBP transcription factorsCell typesHealthy endometriumEndometriosis lesionsProgesterone receptorDecidualization processUterine endometriumStromal fibroblastsMesenchymal transitionProgesterone signalingEndometriumHypoxiaHypoxia pathwayTranscription factorsHuman reproductive successDistinct transcriptional statesExpression of genesJun/Fos
2017
Progesterone-Mediated Non-Classical Signaling
Garg D, Ng S, Baig K, Driggers P, Segars J. Progesterone-Mediated Non-Classical Signaling. Trends In Endocrinology And Metabolism 2017, 28: 656-668. PMID: 28651856, DOI: 10.1016/j.tem.2017.05.006.Peer-Reviewed Original ResearchConceptsProgesterone response elementGrowth factor signalingNon-genomic signalingNon-classical signaling pathwaysNon-classical signalingCycle regulationFactor signalingSignaling pathwaysResponse elementProgesterone signalingCell growthSignalingProgesterone receptorSubsequent activationNovel therapeutic strategiesHormone actionProgesterone actionPathwayGrowth factorImportant physiological actionsPhysiological actionsMenstrual cycle regulationNuclear progesterone receptorRecent studiesActivation
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