2017
Dapsone as a potential treatment option for Henoch-Schönlein Purpura (HSP)
Lee K, Park J, Kim D, Hwang J, Lee G, Hyun J, Heo S, Choi J, Kim M, Kim M, Kim S, Eisenhut M, Kronbichler A, Shin J. Dapsone as a potential treatment option for Henoch-Schönlein Purpura (HSP). Medical Hypotheses 2017, 108: 42-45. PMID: 29055398, DOI: 10.1016/j.mehy.2017.07.018.Peer-Reviewed Original ResearchConceptsHenoch-Schonlein purpuraInterleukin-8Production of tumor necrosis factorHuman umbilical venous endothelial cellsUmbilical venous endothelial cellsPathogenesis of vasculitisProduction of interleukin-8Potential treatment optionEnhanced production of interleukin-8Suppressed interleukin-8Tumor necrosis factorVenous endothelial cellsCentral nervous systemAnti-inflammatory moleculesAnti-inflammatory effectsAnti-leprosy agentsCorticosteroid therapySystemic vasculitisActive diseaseVariable presentationTreatment optionsTherapeutic efficacyNecrosis factorRecommended TreatmentDapsone
2010
The synergistic anti-asthmatic effects of glycyrrhizin and salbutamol
Yang Y, Shi Q, Liu Z, Li R, Pan P, Hou Y, Lu W, Bai G. The synergistic anti-asthmatic effects of glycyrrhizin and salbutamol. Acta Pharmacologica Sinica 2010, 31: 443-449. PMID: 20228825, PMCID: PMC4085675, DOI: 10.1038/aps.2009.207.Peer-Reviewed Original ResearchConceptsEffects of GLAnti-asthmatic effectsAnti-inflammatory effectsInterleukin-8Interleukin-8 ELISAMRNA levelsGuinea pig asthma modelInhibition of NF-kB activationIntracellular cAMP accumulationEfficacy of glycyrrhizinProduction of interleukin-8Anti-asthma therapyReal-time RT-PCRTreatment of asthmaCAMP in vitroBeta2-adrenergic receptorB2-ARNF-kB activationIncreased mRNA levelsCAMP accumulationCombination of GLAsthma modelSalbutamolRT-PCRWestern blotting
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