The synergistic anti-asthmatic effects of glycyrrhizin and salbutamol
Yang Y, Shi Q, Liu Z, Li R, Pan P, Hou Y, Lu W, Bai G. The synergistic anti-asthmatic effects of glycyrrhizin and salbutamol. Acta Pharmacologica Sinica 2010, 31: 443-449. PMID: 20228825, PMCID: PMC4085675, DOI: 10.1038/aps.2009.207.Peer-Reviewed Original ResearchConceptsEffects of GLAnti-asthmatic effectsAnti-inflammatory effectsInterleukin-8Interleukin-8 ELISAMRNA levelsGuinea pig asthma modelInhibition of NF-kB activationIntracellular cAMP accumulationEfficacy of glycyrrhizinProduction of interleukin-8Anti-asthma therapyReal-time RT-PCRTreatment of asthmaCAMP in vitroBeta2-adrenergic receptorB2-ARNF-kB activationIncreased mRNA levelsCAMP accumulationCombination of GLAsthma modelSalbutamolRT-PCRWestern blotting
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