Dapsone as a potential treatment option for Henoch-Schönlein Purpura (HSP)
Lee K, Park J, Kim D, Hwang J, Lee G, Hyun J, Heo S, Choi J, Kim M, Kim M, Kim S, Eisenhut M, Kronbichler A, Shin J. Dapsone as a potential treatment option for Henoch-Schönlein Purpura (HSP). Medical Hypotheses 2017, 108: 42-45. PMID: 29055398, DOI: 10.1016/j.mehy.2017.07.018.Peer-Reviewed Original ResearchConceptsHenoch-Schonlein purpuraInterleukin-8Production of tumor necrosis factorHuman umbilical venous endothelial cellsUmbilical venous endothelial cellsPathogenesis of vasculitisProduction of interleukin-8Potential treatment optionEnhanced production of interleukin-8Suppressed interleukin-8Tumor necrosis factorVenous endothelial cellsCentral nervous systemAnti-inflammatory moleculesAnti-inflammatory effectsAnti-leprosy agentsCorticosteroid therapySystemic vasculitisActive diseaseVariable presentationTreatment optionsTherapeutic efficacyNecrosis factorRecommended TreatmentDapsone
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