2025
The genetic relationship between cannabis use disorder, cannabis use and psychiatric disorders
Galimberti M, Overstreet C, Gupta P, Beck S, Dao C, Deak J, Zhou H, Johnson E, Agrawal A, Stein M, Levey D, Gelernter J. The genetic relationship between cannabis use disorder, cannabis use and psychiatric disorders. Nature Mental Health 2025, 3: 700-708. DOI: 10.1038/s44220-025-00440-4.Peer-Reviewed Original ResearchGenomic structural equation modelingCannabis use disorderCannabis usePsychiatric disordersUse disorderStructural equation modelingIncreased rates of psychiatric disordersIncreasing prevalence of cannabis useRates of psychiatric disordersPrevalence of cannabis useThree-factor modelEquation modelingDepressive disorderPsychiatric traitsCannabisLocal genetic correlationDisordersGenetic correlationsMendelian randomization analysisTraitsRandomization analysisSchizophreniaADHDColocalization analysisIncreased riskTranscriptomic Alterations Induced by Tetrahydrocannabinol in SIV/HIV Infection: A Systematic Review
Valizadeh A, Veenhuis R, Bradley B, Xu K. Transcriptomic Alterations Induced by Tetrahydrocannabinol in SIV/HIV Infection: A Systematic Review. International Journal Of Molecular Sciences 2025, 26: 2598. PMID: 40141240, PMCID: PMC11942185, DOI: 10.3390/ijms26062598.Peer-Reviewed Original ResearchConceptsSimian immunodeficiency virus (SIV)-infected macaquesPrevalence of cannabis useSIV-infected macaquesChronic immune activationHIV-infected human cellsEpithelial cell proliferationModulate immune responsesSystematic reviewSIV/HIV infectionHIV infectionPreclinical evidencePathways related to inflammationImmune activationCannabis useMicro-RNA expressionImmunomodulatory roleImmunomodulatory effectsReduce inflammationImmune responseTetrahydrocannabinolComprehensive searchCell proliferationTranscriptomic alterationsMethodological qualityPWH
2024
Cannabis Exposure and Adverse Pregnancy Outcomes Related to Placental Function
Metz T, Allshouse A, McMillin G, Greene T, Chung J, Grobman W, Haas D, Mercer B, Parry S, Reddy U, Saade G, Simhan H, Silver R. Cannabis Exposure and Adverse Pregnancy Outcomes Related to Placental Function. Obstetric Anesthesia Digest 2024, 44: 139-140. DOI: 10.1097/01.aoa.0001026572.72882.bd.Peer-Reviewed Original ResearchExposure to cannabisCannabis usePlacental functionPregnancy outcomesPrevalence of cannabis usePoor fetal growthAdverse pregnancy outcomesInfluence pregnancy outcomePlacental dysfunctionCannabis exposureFetal growthPregnant individualsSelf-reported useTobacco useCannabisDrug usePregnancyOutcome relationsPotential legal consequencesOutcomesAssociationExposureUseDysfunctionPublished research
2021
Evidence for an increase in cannabis use in Iran – A systematic review and trend analysis
Rostam-Abadi Y, Gholami J, Amin-Esmaeili M, Baheshmat S, Hamzehzadeh M, Rafiemanesh H, Nasserbakht M, Ghalichi L, Safarcherati A, Taremian F, Mojtabai R, Rahimi-Movaghar A. Evidence for an increase in cannabis use in Iran – A systematic review and trend analysis. PLOS ONE 2021, 16: e0256563. PMID: 34460847, PMCID: PMC8404985, DOI: 10.1371/journal.pone.0256563.Peer-Reviewed Original ResearchConceptsCannabis use disorderCannabis useUse disorderPrevalence of cannabis use disorderTrends of cannabis usePrevalence of cannabis useGeneral populationPrevalence estimatesHigh-risk groupIranian general populationRandom-effects modelPooled prevalence estimatePooled prevalenceYouth groupsCannabisA Systematic ReviewSex subgroupsIllicit substancesIranian databasesPrevalenceSystematic reviewNational studyFemale university studentsDisordersMale
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